Acne Rosacea: [rosacea] Re: No evidence that rosacea is primarily a vascular disorder

Wednesday, December 13, 2006

[rosacea] Re: No evidence that rosacea is primarily a vascular disorder

Wow. Interesting! "the vessels do not seem abnormally fragile so
the main abnormality is probably in the dermis surrounding blood
vessels rather than in vessel walls." Maybe it's with the collagen.
Collagen supports vessels. Over time, RLT enlarges the collagen
fibers. Maybe that's part of why it helps, along with the anti-
inflammatory effects.

Cheers!

Artist

--- In rosacea-support@yahoogroups.com, "Brady Barrows" <brady@...>
wrote:
>
> According to Thomas Jansen, MD and Gerd Plewig, MD, "there is no
direct
> evidence that rosacea is primarily a vascular disorder." This to me
is news
> since I have been hearing for so long that rosacea is primarily a
vascular
> disorder.
>
> Here is part of what the article says:
>
> "The pathogenesis of rosacea thus remains obscure. What is certain,
however,
> is that rosacea patients are constitutionally predisposed to
blushing and
> flushing. The basic abnormality seems to be a microcirculatory
disturbance
> of the function of the facial angular veins. Statistical
associations between
> rosacea-related flushing and migraine suggest a shared disorder of
vascular
> regulation but there is no direct evidence that rosacea is primarily
a vascular
> disorder. The response of the facial vessels to adrenaline,
histamine and
> acetylcholine is normal, and the vessels do not seem abnormally
fragile so
> the main abnormality is probably in the dermis surrounding blood
vessels
> rather than in vessel walls. In addition, the distribution of
rosacea is not
> identical with the flush area. A very important background feature
is
> sun damage. Rosacea is always associated with solar elastosis and
often with
> heliodermatosis. Fair-skinned patients with rosacea type I will
often give a
> history of sun sensitivity. " > Rosacea: classification and
treatment,
> Thomas Jansen, MD and Gerd Plewig, MD
>
> source >
>
> http://www.pubmedcentral.nih.gov/picrender.fcgi?
artid=1296179&blobtype=pdf
>
> html version >
>
> http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1296179
>
> For more information on the cause of rosacea go to this url >
>
> http://www.rosaceans.com/html/cause.html
>
> Dr. Plewig is a member of the Medical Advisory Committee for the
RRDi >
>
> http://www.irosacea.org/mac.php
>