Tuesday, December 13, 2011

Rosacea News November 2011

1. FDA Approved 35 New Drugs in FY 2011

The FDA announced today that the U.S. Food and Drug Administration approved 35 new medicines in fiscal year 2011. They included “important advances for patients, including: two new treatments for hepatitis C; a drug for late-stage prostate cancer; …

2. Topical Ivermectin + Metrogel from Galderma

An update to the 2009 filing of the patent covering preparations of Ivermectin and Metronidazole has emerged at the USPTO Patent Application Site. That application was in turn a followup to the original French language application 0505918 from 2005. The patent covers many different combinations of ivermectin and metronidazole such as emulsion, cream, gel with ivermectin present in an amount of from 0.01% to …

3. Amneal Pharmaceuticals joins the Generic Oracea War

News today of yet another company in the courts fighting against Galderma for the right to make Generic Oracea. Amneal Pharmaceuticals, based in Gujarat, India, a producer of generic …

4. Pineapple + Cottage Cheese, Get Bromelain from your fridge

Are you searching for a natural therapy to quickly relieve your symptoms? Would you be willing to try freshly crushed pineapple and cottage cheese on your face? Ellen …

5. Scenesse One Step Closer for Erythropoietic Protoporphyria (EPP)

News from Clinuvel that Scenesse (their implant of afamelanotide 16mg) has shown a provable positive effect on EPP sufferers in a US Phase 2 Trial. EPP is an acute intolerance to exposure to sunlight and UV. Sufferers of …

6. Accutane Gaining More Popularity

A new paper that highlights the progress made in recent years by researchers who are seeking to prove that accutane is a viable rosacea treatment.

This growing body of proof is actually quite important because oral isotretinoin is not officially approved as a treatment for rosacea. Doctors can prescribe accutane off-label for use in rosacea, so more comprehensive trials of accutane can only be a good thing. Further, the growing difficulty in finding a doctor who will actually prescribe accutane means that rosacea sufferers need all the proof that they can get their hands on.

Tuesday, October 04, 2011

Rosacea News September 2011

1. Sanofi-Pasteur to make an Acne Vaccine

A vaccine for acne ? Well it appears that one may actually become a reality. A recent article in the New Scientists explains how targeting a protein called CAMP can …

2. Galderma wanting to show Oracea Maintains Rosacea Remission

A recently posted proposed Clinical Trial has me thinking that Galderma wants to be able to market Oracea as a product to Maintain Rosacea Remission. First Some History …

3. Placebos Get Better Over Time: The Weird World of Placebos

More from the weird and wonderful world of clinical trials and the mysterious Placebo Effect. We know that somehow even dummy pills can kick-start the body’s recovery engine. This latest article from WIRED tells us that drug …

4. Diet and Acne: What the Latest Research Says

September 16th, 2011, by David Pascoe | acne treatments, diet | Edit

Over at the Acne Blog, Daniel Kern has posted a few high level posts relating to recent readings he has undertaken on the topic of diet and acne. Daniel …

5. Oracea set to generate $260m in 2011

An interesting note from the detailed interim judgement in the ongoing patent dispute between Galderma and Mylan. As part of the proceedings Mylan looked at the on-going Oracea sales and projected that Galderma can expect to receive around $260 million in 2011. MYLAN PHARMACEUTICALS INC., v.  GALDERMA LABORATORIES, L.P.; et. al. …

Monday, September 26, 2011

Rosacea News August 2011

1. Melanin also Protects You from Radiation !

Startling news today from the Clinuvel Blog: Melanin also has the ability to protect from radioactive emissions like X-rays and Gamma-rays. How interesting that the chemical that …

2. Mylan Violates The Chang Patent for Oracea

Another step in the ongoing battle between Galderma and Mylan over the right to manufacture generic Oracea. A judge has declared that Mylan infringes 1 of the patents that protects Oracea from generic copies. Some History …

3. How Much Sunscreen Should I Use?

Another fabulous data visualisation from Information is Beautiful. This time David McCandless tackles the thorny issue of How Much Suncreen Should I Wear ? The Sunscreen Smokescreen July 11, 2011 It started with a question. It always does. This time, the question was simple: How much sunscreen should I wear? I’m …

4. NRS Funds New Rosacea Studies for 2011

In the Summer 2011 Rosacea Review, The National Rosacea Society announced that they are funding 3 studies in new areas of rosacea research. This is great news; not only is the NRS continuing to fund 5 existing studies, it is funding …

5. NRS Continues Leading Edge Research Funding

The National Rosacea Society recently announced that they will be continuing to fund 5 existing rosacea research streams. Confirming their faith in the on-going NRS sponsored research, the NRS has announced additional funding to the following researchers. 1. Dr. …

6. Lupin and Medicis Agree Over Generic Solodyn

In contrast to the ongoing disputes over generic Oracea, the makers of the low-dose minocycline Solodyn, Medicis have entered into a joint development and sales agreement with Lupin Pharmaceuticals.

Solodyn is a form of Minocycline, a member of the tetracycline famaily, available in 8 strengths, prescribed based primarily on your weight.

7. Low Dose Accutane from St Thomas’ Hospital in London: Daily Mail

The Daily Mail has another of its semi-regular stories on Rosacea today. This time the article highlights the use of low dose accutane to treat hyper keratinisation, slow down sebum production, and also serve as an anti-inflammatory and anti-bacterial agent.

Rosacea News July 2011

1. Visualising Evidence for Oral Supplements: Snake Oil All Round

Below is a wonderfully rich graphic that tries to help visualise the available evidence for the efficacy of dozens of oral supplements. The aim of the creators is to visualise tangible health benefits when taken orally by an adult with a healthy diet. Only human, randomised placebo-controlled trials were used to create this graphic. Information is Beautiful: Snake Oil? …

2. Gallo to trial Aminocaproic Acid as Cathelicidin Inhibitor

Just posted are some details of a new trial rising out of the work of Dr. Richard Gallo’s group at the University of California, San Diego. Gallo is well known for his work on the relationship between antimicrobial peptides such as cathelicidin, and rosacea. The trial will compare topical 25% aminocaproic acid (ACA) mixed with Vanicream vs Vanicream on its own. The …

3. Allergan buying Vicept Therapeutics to get V-101 / Oxymetazoline

News today that Allergan are buying the privately held pharmaceutical company Vicept Therapuetics. The aim of many small startup companies is to be acquired by a larger company, Vicept telling us that “We believe Allergan …

4. Rosacea Cure eBooks: All Just SPAM?

There is a seedy dark side to the internet. OK you knew that already, but perhaps there are forces at play on the internet that are more subtle than you realise. Lets turn our focus toward the emergence of the “Rosacea Cure eBook” Phenomenon. Over the last few years there are more and more web sites that exist to solely sell you …

5. Metrogel, Finacea and Oracea are Best for Rosacea

A systematic review of the available rosacea research confirms that Metrogel, Finacea and Oracea are effective for moderate to severe rosacea. One study further found cyclosporine 0.05% ophthalmic emulsion effective for ocular rosacea. This review looked at the published results of 58 trials to note bias and construct a high level summary of the results. No Surprises Here It will come as …

6. Cosmetics and Makeup work fine applied after Metrogel

This research comes up with the finding that using a foundation after applying Metrogel 1% won’t worsen rosacea symptoms. Most of the participants in the trial were happy with the appearance of foundation, when used in combination with Metrogel.

The authors tell us that there is little research into whether makeup both makes rosacea worse or whether those who suffer from rosacea can also successfully use makeup like foundation.

Friday, August 12, 2011

Rosacea News June 2011

1. 9 New Drugs in Development for Rosacea

The Pharmaceutical Research and Manufacturers of America tells us that there are currently 9 drugs in development for rosacea. I was initially curious as to how counted nine. Read on if you want to see how they get to this number. 277 Medicines in Development For Skin Diseases Washington, D.C. (June 13, 2011) — America’s biopharmaceutical …

2. Why Do New Drugs take SO LONG to be Developed?

For everyone waiting on the latest and greatest new treatment for rosacea, new drugs seem to take forever to make it to the market. Taking a step back and looking at new drug development in general, it is very sobering to read how few drugs actually make it to an approved product; THE DRUG DISCOVERY , DEVELOPMENT AND …

3. Final FDA Approval of Sansrosa, expect 15 months post Phase III

A popular topic online at the various rosacea forums is to guess when Sansrosa will become available. So far all guesses have proved way way too optimistic. Given that we believe that the process is in the later stages of Phase III, what sort of best outcome possible, educated guess might be worth offering up? Once the Phase III process completes (which itself …

4. Riversol: From idea to a Rosacea Product

I thought this article from the Vancouver Sun was quite interesting from the point of view of developing new products for rosacea sufferers. Just how do you get from something that you think might work, to a product …

5. Galderma blocking Impax making Generic Oracea

The last we heard from Impax Laboratories was in late 2009 when they had filed an Abbreviated New Drug  Application (ANDA 91-447) to produce a generic version of Oracea. …

6. Inactive Ingredients Just as Important as Active Ingredients

Rosacea sufferers get good at looking through ingredient listings. What magical ingredient has been included in this product that might help me? But you should keep reading and take notice of everything listed.

7. How do you cope with Rosacea at Work?

The NRS recently highlighted the possible negative effects of rosacea in the workplace and on their career.

As well any physical symptoms such as facial burning, blurred vision and debilitating flushing, the secondary worries about what others will think about your appearance make it tough for rosacea sufferers at work.

Thursday, June 16, 2011

Rosacea News May 2011

1. Custom Cleanser and Moisturizer from acne.org

The owner of the site acne.org, Daniel Kern has created an acne treatment regime that is cheap and simple. It looks to me like any benefits to rosacea sufferers are yet to be discovered. acne.org is a large online community of acne suffers that includes a small area for rosacea sufferers. The site is run mostly by volunteers and doesn’t accept any …

2. Most Patients use Steroids for Trivial Problems

Steroid Induced Rosacea is, sadly, one hot topic.

I know this because the blog posting Treating Steroid Induced Rosacea is one of the most visited pages on this site, and is currently approaching 1000 comments. Unfortunately many …

3. Sansrosa Parallel Phase III Safety and Efficacy Trial Announced

News today of a parallel Sansrosa Phase III Trial. This just announced trial is shorter than the Long Term (52 week) Safety Trial, and seeks to confirm that Sansrosa Gel (CD07805/47) is more effective than the inactive vehicle gel and is itself a safe treatment. Trial ID: NCT01355458 (seems to be somewhat duplicated with NCT01355471) …

4. Vanicream Moisturizing Skin Cream User Reviews

I harp on about this a lot, but I think it is worth repeating. A gentle skin care regime is a good thing for your rosacea. We know …

5. Tetrapeptide-14: Now available for Eye Puffiness and Redness

Some news today promoting a product claimed to reduce the appearance of under eye puffiness. Tarte Dark Circle Defense claims the inclusion of a Helix Biomedix designed peptide sequence known as Tetrapeptide-14 is responsible for the anti-inflammatory actions of the concealer.

6. AzaClear: Moisturizer with Azelaic Acid and Niacinamide

Epikinetics Pharma has pushed out a press release today (reproduced in full on sfgate.com …

7. Why should I Cleanse and Moisturize my dry, oily, flaky SD skin?

I came across this thread in the archives and thought it was worth highlighting it and pushing it out again.

The question asked is a good one – how can cleansing and moisturizing the dry flaky and oily SD skin be a good thing? If you have ever wondered why this is so, read on.

It was interesting to read again how for severely sensitive skin, repairing …

8. FTC Gets Tough on Acai Berry Supplement Sites

Recently the Federal Trade Commission announced that it was taking legal action against businesses that operate deceptive supplement web sites, specifically sites that selling Acai Berry based products.
What does this have to do with Rosacea?
A fair question. As the internet has become a more and more popular source for health related information, the trustworthiness of web sites has become more and more important.

9. Atopiclair, Eletone, MimyX: Barrier Creams with No Active Ingredients

Thanks to Beth, here is some more information about a class of FDA Approved “Medical Device” creams. This class of creams are prescription only, contain no active molecules and are approved for sale to treat medical conditions under via the provisions of …

Wednesday, May 11, 2011

Rosacea News April 2011

Rosacea News April 2011

1. LA Clinic looking for Oracea Biomarkers Study Participants

The Vitligo and Pigmentation Institute of Southern California is hosting part of the trial to evaluate Rosacea-related Inflammatory Biochemical Markers in Adult Skin When Treated With Oracea  vs Placebo. This trial is looking to prove changes in inflammatory markers like the peptide LL-37 and the MMP family match the improvement seen when taking Oracea. The trial is scheduled to involve 170 participants at …

2. Why, Oh Why Did I Get Rosacea ?

I hear you.

My skin was great. I have had beautiful skin all my life, but now wham! rosacea has reared its ugly head.

Well the NRS Blog has an answer to this plea. It is all about your risk profile. If you are over 30 with fair skin, have a relative with rosacea and are of Northern European Ancestry then the statistics suggest that you are …

3. Galderma Big Profits Great for Texas

An interesting article from the Business section of the Star-Telegram about the local presence of Galderma in Fort Worth, Texas. Galderma is one of the key companies for rosacea sufferers to follow given their products such as Cetaphil, Metrogel, Oracea and the in-development Sansrosa. Swiss skin-care company thrives even during hard times, executive notes at …

4. Vicept Oxymetazoline V-101 Cream More Phase II Data, on to Phase III

A Press Release today (Vicept are happy to generate publicity at every step of their development) touting more Phase II Study results for their Oxymetazoline based V-101 product. V-101 is a topical slated to treat the redness of …

5. The BEST Treatment for Rosacea

Once you have been diagnosed with rosacea, everyone naturally wants to know What is the best treatment for rosacea? Wouldn’t it be great if there was a simple answer to this question that satisfied everyone who has rosacea! Hopefully it doesn’t come as a surprise to find out that there is no known panacea for rosacea. This high level paper …

6. Generic Oracea Legal Trial now in July 2011

I have been watching for a while to see for any developments in the legal proceedings between Mylan and Galderma. These proceedings will determine whether Mylan is allowed to sell Generic Oracea. This is of interest to many rosacea sufferers who consider that Oracea is too …

7. Medicis and Anacor to Develop Boron Treatments for Acne

Even though this press release relates to Acne, it is still interesting to see companies searching for the next killer acne treatment. Whilst only some acne treatments are successful as rosacea treatments, we can still …

8. Green Jelly Beans Linked to Acne!

OK so now I have gotten your attention. Have read of this comic. Lets talk after you finish reading it. xkcd: Significant …

9. Nailfold Capillaroscopy: If only Rosacea was that Easy to Diagnose

I thought this abstract was interesting because of its failure. The authors proposed that a passive diagnostic test known as Nailfold Cappillaroscopy could be used to test for rosacea.

Monday, April 11, 2011

Rosacea News March 2011

1. Gallo: beta-defensins coordinate Skin Barrier Injuries

This short abstract from Dr. Richard Gallo is an introduction to an article further on in the journal edition from Dr. Ahrens et al. Gallo’s interest is piqued by the possibility of a coordinated defense effort from the permeability and antimicrobial barriers of the skin. Ahrens was able to show that certain Antimicrobial peptides (AMPs), called beta-defensins were upregulated (i.e. they …

2. Dry Eye is a common precursor to Ocular Rosacea

This abstract suggests that dry eye may be an early sign of ocular rosacea. Tear function tests could help the early diagnosis of ocular rosacea, according to the authors. Currently there is no definitive diagnostic test for ocular rosacea, it is based on clinical symptoms. One proposed diagnostic test is high abundance of oligosaccharides in the tear fluid of patients with rosacea. …

3. Ever heard of a Rx Cream with NO ACTIVE INGREDIENTS?

In all of your internet searching for treatments, have you ever come across a FDA approved, prescription-only treatment that claims to have no active ingredients ? Would you stop and think What is that all about? Well I did. The supporting web site for Promiseb Topical Cream  (online at http://promiseb.com/) contains a very …

4. Itchy Gritty Eyes may be Blepharitis

An unusually useful article about Blepharitis today from The Herald Times Reporter, Manitowoc, Wisconsin. (htrnews.com). Itchy, sandy feeling in eyelids may be blepharitis Question: What causes my eyelids to be itchy and sandy in the mornings? Answer: The most likely cause of your symptoms is something called blepharitis, or inflammation of the eyelids, and …

5. Sansrosa starts Phase 3 Trials (again)

News today that Galderma has listed CD07805/47 as entering large scale Phase III trials. Under the previous owners of the Brimonidine-based technology Collagenex, the product then known as Sansrosa …

6. The Rosacea App: A Rosacea Web Site in your pocket

This is a first. A major pharmaceutical company has released a smart phone app for rosacea sufferers. Intendis, the makers of Finacea, have created a program that you can carry around for easy reference.

Built with the help …

7. Finacea plus Low Dose Accutane to treat Seborrheic Dermatitis + Rosacea + AK

Below is a recent paper suggesting that combining Finacea with Low Dose Accutane is a useful treatment for rosacea concomitant with seborrheic dermatitis. The patient was also suffering from Actinic Keratosis (pre-cancerous skin lesions). The patient experienced relief from both rosacea and seborrheic dermatitis, two conditions that together sometimes prove tricky to treat. Bear in mind, though, that this paper …

8. Intendis makes a mobile phone app for Rosacea

Intendis, the makers of Finacea, have announced that they are to produce an application for mobile phones to help sufferers of rosacea manage their symptoms. To be launched in March, the Rosacea Info App will be available for iPhone, BlackBerry and Android. Previously Rosacea News covered a program called AcneApp that purported to treat acne by displaying a solid red or …

9. Galderma, with Oracea looking for Inflammatory Pathway Markers

Seemingly wanting to help answer the question How do tetracyclines help Rosacea? Galderma has announced a large trial to measure the changes in inflammatory pathway markers when you take Oracea.

Whilst the trial only directly mentions LL-37 and MMP I would expect other well known markers to be measured as well.

If the researchers include markers that can be proven to be indicative of rosacea disease, …

10, The Placebo Effect is a very strange thing indeed

How exactly does the mind play a role in the way that medicines help us ? How come even when we know the treatment is fake, we can get better ? Should we be asking our doctor for a bottle of placebo pills the next time we visit ? I would love to know the answer to these questions and …

11. Xylometazoline (Otrivin) is another red face treatment

A brief extract today covering a paper detailing how the topical Xylometazoline can be used to treat the redness of rosacea.

Similar to oxymetazoline, xylometazoline is marketed as a nasal decongestant under many brand names. Brands you may come across include Otrivine, Otrivin, Sinutab Nasal Spray, Cirovin and Novorin.

Thursday, March 03, 2011

Rosacea News February 2011

Rosacea News February 2011

1. 4% Quassia Amara Extract as good as Metrogel and Finacea

A just published abstract introduces a botanical extract for the treatment of rosacea. Researchers from the National University of Córdoba in Spain compared a topical gel containing 4% Quassia Amara with Metrogel and Finacea. The extract compared favourably to these established rosacea topicals, and thus might offer an alternative …

2. Tea Tree Oil may help skin cancer lesions

Some recent studies highlighted today from the University of Western Australia’s Tea Tree Oil Research Group. Who would have known that tea tree oil was interesting enough to have its own research group! Tea tree oil is interesting to rosacea sufferers firstly because it has been shown that tea tree oil can demodex mites. Secondly there is some research that shows that tea tree …

3. Bad Acne can lead to suicidal thoughts in teenagers

This study, undertaken in Norway finds that bad acne can of its own accord, induce suicidal thoughts in teenagers. Being a teenager can be tough. Being a teenager with bad skin and good mental health can be even tougher. If this study bears out in the larger population, then it is worth knowing that acne alone can be responsible for teenagers, most …

4. Neuropeptide PACAP Modulators for Neurogenic Rosacea

The recently published paper that called for the creation of Neurogenic Rosacea subtype contained an interesting disclosure.

We are told that one of the paper’s authors, Professor Martin Steinhoff MD PhD , holds a related patent and research grant from Galderma.
Related Rosacea Grant
Dr. Steinhoff, along with Dr. Feramisco, received a $25,000 grant in 2010 from the National Rosacea Society.

Perhaps this below is the grant …

5. How do you treat Neurogenic Rosacea?

This article is the third in a series featuring Neurogenic Rosacea. The first two articles are here: Neurogenic Rosacea: a new subtype for those with dysfunctional facial nerves and What is Neurogenic Rosacea?

Recently a group of doctors from Stanford became the first to publish a …

6. What is Neurogenic Rosacea?

A recent paper in Archives of Dermatology proposed a new rosacea subtype that is to be called Neurogenic Rosacea.

Before we tackle the question of What is neurogenic rosacea?, and How do I know if I have it?, lets step back and look at why a new subtype might be helpful.

7. Neurogenic Rosacea: a new subtype for those with dysfunctional facial nerves

A just-published paper in the Archives of Dermatology is calling for the recognition of a new rosacea subtype – Neurogenic Rosacea.

Thursday, February 03, 2011

Rosacea News January 2011

Rosacea News January 2011

1. SkinMedica Redness Relief CalmPlex launches to replace Cutanix DRL

We were tipped off by a comment on the blog posting about Cutanix going offline, to the possible future availability of a Cutanix like product. The commenter, who works for SkinMedica told us that; skincarejunkie Bioform was sold to Merz Aesthetics. In that sale Cutanix was sold to SkinMedica. …

2. AAD: your Vitamin D should come from diet, not the sun

Thanks for the tip from the Clinuvel Blog. The AAD has issued an Updated Position Statement on Vitamin D. The AAD’s position is that there is NO SAFE THRESHOLD for sun or indoor tanning exposure, and that we ought to get our recommended daily allowance for Vitamin D from our diet.

3. Sansrosa delayed, sufferers make their own Brimonidine, BEWARE

The path from the laboratory for Sansrosa / COL-118 / CD07805/47 to a product that realises the promise of permanently reducing  a red face has been a long one. We first heard about a product to become known …

4. Cutis posts Oracea Phase 4 (ORCA) papers for free online

Late last year Galderma generated quite a lot of publicity in the lead up to the release of the Phase 4 trials of Oracea. Phase IV trials typically …

5. Aczone is as good as Oracea, Finacea or Metrogel, apparently

Trolling patent applications is pretty turgid work. Mostly patents seem to be intellectuals marking out their claims in the hope that future products might result from their discoveries. This patent application starts badly with firstly spelling Rosacea incorrectly as Rosascea.

6. Combining Ivermectin + Benzoyl Peroxide in a topical

A recently updated patent, assigned to Galderma suggests a rosacea topical comprising “at least one compound of the avermectin family and benzoyl peroxide”. This is an unusual (or novel, depending on your viewpoint I suppose) pairing of ingredients for a topical treatment for rosacea symptoms. If you search patents online you can also find applications for topicals containing Avermectin + Metronidazole and …

7. Book Review: Acne and Rosacea The Complete Guide, Alison Bowser

The book is written in 3 parts – 1. Acne (135 pages), 2. Rosacea (25 pages) and 3. Caring for Acne and Rosacea Skin (39 pages).

8. Top Blog Posts on rosacea-support.org

Now that 2010 is over, a quick look at the overall most popular pages on rosacea-support.org. Most Popular Posts Overall The following 10 web site pages were the most popular overall for the year: Photos of Red Nose, Papules, Pustules, acne like rosacea How to Cure a Red Face (facial erythema or …

Monday, January 03, 2011

Top Blog Posts on rosacea-support.org

Now that 2010 is over, a quick look at the overall most popular pages on rosacea-support.org.

Most Popular Posts Overall

The following 10 web site pages were the most popular overall for the year:

Most Commented Posts

The following are the top 10 most commented posts on the site:

Rosacea News put up 108 new posts during 2010. Not a huge number, but hopefully everyone might agree that quality is more important than quantity.

Rosacea News December 2010

1. Lupin Pharmaceuticals also files ANDA for Generic Oracea

The battle to make generic Oracea available to the public is heating up. Recently filed documents in Delaware show that Lupin Pharmaceuticals, which are based in India have filed for …

2. Laser still the best for Spider Veins on the Face (WSJ)

An article today in the Wall Street Journal’s Health Aches & Claims section discusses treatments that are available to remove spider veins that can develop on the face. The author quotes Dr. David Goldberg who is well know to rosacea sufferers as a director of Skin Laser & Surgery Specialists of New York and New Jersey and a clinical professor of dermatology and director …

3. Rosaclear from Obagi as an Integrated Rosacea Treatment Regime

The idea of using an American Academy of Dermatology Poster session paper to introduce research around a new product is nothing new. Getting a poster session approved is easier than a full …

4. Doxycycline is as good as Low Dose Accutane (0.3mg/kg/day)

This study as described in a AAD Poster Session, compared 3 different doses of isotretinoin/accutane with a somewhat standard low dose  regime of doxycyline.  The study was able to show that 0.3mg/kg/day of accutane was as effective as 100mg of Doxycycline for 14 days; followed by 50mg a day thereafter. A dose of accutane of 0.3mg/kg/day is 18mg per day for a …

5. Finacea Foam vs. Finacea Gel

This time last year we learned that Finacea Foam was being trialled for rosacea. That 2009 initiated trial was to compare Finacea Foam against the placebo foam vehicle.

Now a new trial has been listed to compare Finacea Gel with Finacea Foam.

As I noted a year ago, these kind of `swings and roundabouts’ trials tend to be seen when a product reaches maturity and the …

6. What role do micro-organisms in play in Rosacea?

This abstract promises to tell us everything we need to know about the possible role of micro-organisms in the way that the disease Rosacea starts and develops. Even though the role of published research is not to provide reading material for the general public, I still look to journal …

7. Sunscreen does indeed help prevent Melanoma

Apparently this is new information; a study has for the firs time found evidence that sunscreen can help prevent the deadly skin cancer melanoma.

I had assumed that this was a well known fact, but this is not …

8. Rosacea’s Inflammation Mechanisms: Symposium Notes

Thanks for the tip from Dan, here is an interesting presentation from the AAD Summer Academy Meeting, August 4-8, Chicago, Ill. The notes are titled Acne and Rosacea: Inflammatory mechanisms and their impact on therapy and were part of Symposium S012. The Symposium was titled What’s Breaking Out: Acne and Rosacea. Dr. Bhatia was the first speaker, and was down to cover this …

9. Topical Timolol (Timoptic) for rosacea lesions around the eye

A new clinical trial is proposing to look at using a non-cardioselective beta-blocker, Timolol Opthalmic, to treat ocular rosacea based benign vascular lesions on the eyelid. The condition is chronic as it can lead to blindness. Timolol has been used orally in the treatment for hypertension and opthalmic solutions have been used to reduce intraocular pressure in glaucoma. Clinical …