Well we finally know what Galderma will be calling their ivermectin cream – Soolantra.
Visit all my Soolantra Articles for more information about this just released topical.
Soolantra before and after pictures
How well does Soolantra work ? If you have the papules and pustules of rosacea, what kind of results might you expect ? Well Galderma have released an impressive pair of before and after photographs of someone who has used Soolantra for 12 weeks. Soolantra Before Picture Here the trialist is a the `baseline’ before …
Galderma announces approval of Soolantra
Galderma has announced today that their 1% Ivermectin cream in development for rosacea as CD5024 has been approved and is now known as Soolantra. Soolantra appears to be going to be promoted as a treatment that is quicker and more effective than Metrogel 0.75%. Soolantra has been in development as CD5024 for many years. …
Cutera, the makers of the Cutera Excel V, a 532nm KTP Laser have posted the details of trial comparing their product with the 595nm Pulse Dye Laser from Syneron Candela. The physician and trialist will assess improvements in the blood vessels and pustules and papules of rosacea. Additionally the trial will use a Spectrophotometer to […]
Clinuvel have announced that their treatment known as SCENESSE (yes another product insisting on all caps) has been approved as a treatment for Erythropoietic Protoporphyria (EPP) in Europe. SCENESSE has previously been granted Orphan Drug Designation in Europe, USA, Australia and Switzerland. Scenesse was approved for use in Italy in 2010. Europe approves novel Australian […]
File this one away with the unusual and `maybe not the whole story’ research results. Recently publicised research shows that rosacea sufferers are 10 times more likely to have food allergies compared to non rosacea sufferers. Additionally the research found a 7.5 times likelihood of having urogenital disorders. Rosacea’s comorbidities are more than skin deep […]
Looking more like a sunscreen with some herbal extracts Dermalex Repair has made a gentle entrance to the rosacea market in the UK. Described as a `treatment cream for Rosacea and Couperose’ Dermalex seems to be a mild and reasonably priced skincare cream. The product publicity includes the following grand sounding claims’ The patented Tri-solve® […]
More finger pointing towards the peptide LL-37 and its role in the inflammation associated with rosacea. This abstract tells us that the inflammation and extra blood vessels associated with exposure to the sun (specifically the UVB band of radiation) are enhanced in the presence of cathelicidin LL-37. This result may help explain why sun exposure […]
With all of the terrible articles you can find on the net about demodex mites (delighting to tell us about about how they eat, defecate and reproduce in your skin; and how they are actually `spiders’) it is nice to read a well written article full of real facts about demodex mites. You Almost Certainly […]
Despite suggestions that Generic Metrogel is easily available in the US, there are scant reports online from users getting access to cheaper Metronidazole 1% treatments. In July this year Sandoz announced that they were selling a generic version of Metrogel 1%. The generic versions of metronidazole gel were previously restricted to 0.75% as the patent […]
Galderma have added a page to the Mirvaso web site to guide doctors dealing with the potential for “rebound” by users of Mirvaso. This would seem to confirm that Galderma is aware that there are users of MIRVASO who are experiencing adverse events. The use of double quotes around “rebound” and “worsening” is interesting and […]
The latest edition of the Journal of American Academy of Dermatology lists an exchange by letter detailing a contact dermatitis allergic reaction to Mirvaso. The adverse reaction was found by the doctors to be caused by the main active ingredient in Mirvaso, Brimonidine. The writers of the letter to the JAAD caution other doctors that […]
We don’t often get to see research results published that show a proposed new treatment doesn’t work. It make sense that researchers and pharmaceutical companies would rather see their research and development efforts succeed and lead only to new products. A clinical trial for MK-0524, Merck’s designation for their product known as Laropiprant, has confirmed […]
Some just published research from the Ivermectin Phase III study group suggests that Ivermectin 1% cream once a day is better than Metronidazole 0.75% twice a day at treating the papules and pustules of rosacea. The British Journal of Dermatology paper tells us that although both Ivermectin and Metronidazole did lead to a reduction in […]
Some friendly words from the Irish Examiner recently seeking to create an Irish link to the topical treatment known as Rossoseq. According to the article Rossoseq is being made available firstly in Ireland. Rossoseq has been associated with a mild reduction in redness in a small trial of 10 users. What is Rossoseq? The product […]
According to the Galderma AU web site, Mirvaso is now available in Australia. Here are the Australian versions of the MIRVASO Gel User Consumer Information and also Mirvaso Product Information. Mirvaso was first registered in the Australian Register of Therapeutic Goods on the 4th of August 2014. See the listing here – MIRVASO CMI Mirvaso […]
Bayer HealthCare has announced positive results from a Phase III trial that evaluated the safety and efficacy of a foam formulation of Finacea – 15% azelaic acid. Last we heard from Finacea Foam was results from trials in 2011 where 401 patients were trialled. This study examined how well finacea foam performed compared to the […]
Users of ONRELTEA in Canada who have bad reactions or `adverse events’ related to using this newly approved product are reminded in the ONRELTEA Product Monograph to report these events. The body responsible for supervising prescription drugs is the Canada Vigilance Program. The Brimonidine based topical which is available in the US as Mirvaso has […]
Galderma, for reasons unknown, decided to rebrand the newly FDA approved Mirvaso as ONRELTEA in Canada (yes they use all capitals in the brand name). This continues the tradition for Galderma of split North American branding; Oracea in the US is known as Efracea in Canada. There is already some history of user experiences of […]
Rosacea Forum user rosaceaclearwannabe has posted about a recent episode of My Naked Secret that features a participant who was treated with Mirvaso. The show follows Anna who suffers from the red face of rosacea. She is followed as she becomes one of the first people in Europe to try being treated with Mirvaso. The […]
News today that the former owners of the patent covering the product Mirvaso have sued Galderma over a contract dispute. The 5 former owners of Sansrosa say that a contract error will cost them $20m. Sansrosa, who was then owned by Collagenex was sold to Galderma in 2008. Galderma asserts a group of patents protect […]
The existence of free drug samples appears to be altering the habits of doctors such that treatments are overall more expensive for patients. This is the result of some research into the prescribing patterns of a group of acne and rosacea patients in 2010. The researchers found that doctors who distributed free drug samples were […]
In September last year a trial was listed to assess whether cromolyn sodium ophthalmic solution 4% could improve the redness associated with rosacea. This trial was listed by Dr. Anna Di Nardo, who is a part of the UCSD and has received NRS funding in 2012 to research the link between Mast Cells and the […]
A paper published in the Georgian Medical News, and listed on PubMed details a study that concludes that Rutin Forte is an effective means for the treatment and prevention of erythematous rosacea. The supplement was included alongside regular rosacea therapy of topical and oral antibiotics. What is Rutin Forte? Rutin Forte is a nutritional supplement […]
Galderma has reached into its bag of trademarks and announced that Mirvaso will be known as ONRELTEA in Canada. Red Faced? Rosacea Sufferers Now Have a New Option Proven to Reduce Facial Redness Health Canada Approves The First and Only Topical Treatment Indicated for the Persistent Facial Erythema of Rosacea THORNHILL, ON, May 21, 2014 […]
Linda Stein Gold mentions in a video posted on Skin and Allergy News, referring to Galderma’s Ivermectin Cream ; Phase 3 Clinical Trials have completed, and FDA Approval is expected later this year (2014). This is great new for those who 1) want to try an approved treatment for demodex mites and 2) may not […]
In mid 2012 we learned that a company called Tissue Tech was going to trial single use T4O wipes as a treatment for ocular demodex mites. Early last year Bio-Tissue Inc., the parent company of Tissue Tech announced the release of Cliradex. This new product is promoted as a tea tree oil based moist towelette […]
First hinted at 2 years ago at the 2012 AAD meeting in San Diego, a new topical from Skinceuticals is now available and is starting to accumulate some modest research suggesting that it is good for a red face. This paper published in the JDD suggests that using Skinceuticals Redness Neutralizer along with the regular […]
Following hot on the heels of the announcement that Mirvaso has been approved across Europe is an update to the UK’s NHS New Drugs website. The Mirvaso page has hinted that the cost of Mirvaso in the UK, when it launches next month, may be as low as £34 a tube. Further, a tube is […]
The clinical trial data for Galderma’s upcoming 1% Ivermectin Cream product (known during development as CD5024) is looking quite good. The data is showing that Ivermectin Cream is able to effectively reduce the papules and pustules of rosacea. There may even be some hints that it has a lower adverse reaction rate compared to its […]
The occurrence of significant rebound redness and stinging after using Mirvaso is beginning to surface more and more in the public eye. This recent letter to the editor in the Journal of the American Academy of Dermatology describes 3 cases of severe reaction to Mirvaso. Patient 1 had “in all areas where the medication had […]
I feel like a bit of a Galderma PR machine at the moment, but Galderma do seem to be doing a lot. Maybe this product is yet another step in Galderma’s quest to own the Rosacea Market. So coming soon is a moist cloth version of Cetaphil Gentle Skin Cleanser. Have you ever wished that […]
Galderma is ramping up its promotion of Mirvaso with the launch of a web site to promote the idea that a red face is just wrong. The site is a funnel page, attempting to direct you over to mirvaso.com. This type of web site is known as a `direct to consumer symptom awareness campaign’ – […]
1. Mirvaso has been approved across Europe
News today that Mirvaso has gained approval or Marketing Authorisation as they call it, by the European Commission. This means that Mirvaso is approved for sale and will soon be available across the European Community, at the will and availability of Galderma. So Mirvaso is now approved for sale in Austria, Belgium, Bulgaria, Croatia, Cyprus, […]
2. Nestle now calling the shots at Galderma
Galderma, the biggest pharmaceutical company of interest to rosacea sufferers has had a subtle, but potentially important change in ownership. Galderma was created in 1981 as a joint venture between L’Oréal and Nestlé and is of course known for their prescription products like Metrogel, Oracea and Mirvaso as well as skincare products like Cetaphil. So […]
3. Mysterious PAC-14028 1% Cream for Red Face
An intriguing clinical trial has surfaced for a cream that is so far unknown to rosacea sufferers. The makers of this cream, which is in Phase 2 trials, Amore Pacific Corporation is located in South Korea. Amore Pacific makes impressively expensive cosmetics. I wonder if anyone has tried their premium products? It is encouraging to see them […]
1. Mirvaso European Availability by March 2014
A Medscape article today announces that Mirvaso has been granted human approval and should be approved for sale across Europe by March 2014. The initial authorisation to market Mirvaso has been granted and are normally issued 67 days from the adoption of the `Summary of opinion’ Mirvaso Gains CHMP Support for Rosacea Erythema Treatment Miriam […]
2. Afrin (Oxymetazoline) Safe Off Label Drug for a Red Face
This paper from Hospital Pharmacy is giving a guarded approval for the use of Oxymetazoline topically for the redness of rosacea. Even though the FDA has not approved Oxymetazoline as a topical skin treatment, it is approved as a nasal decongestant. Doctors are able to prescribe drugs for off-label use, that is once a drug […]
3. AARS, The Best Rosacea Topicals
The American Acne & Rosacea Society have published another paper in their series looking at the state of the art in rosacea treatments. This part is dedicated to rosacea topicals, and how to use them to manage rosacea symptoms. The paper is described as reviewing “topical agents approved by the US Food and Drug Administration […]
4. Topical Ivermectin 0.5% being trialled for Demodicidosis and rosacea papules
A just listed clinical trial shows a continuing interest in the usage of Topical Ivermectin for rosacea like syptoms. This trial will see how well Ivermectin can treat Demodicidosis and the associated symptoms of redness, dryness, itch, roughness and scaling. What is Demodicidosis? Demodicidosis is a condition where there is an infestation of demodex mites. […]
5. Rosacea coverage at AAD Denver 2014
The annual meeting of the American Academy of Dermatology is to be held in March in Denver, Colorado. The popularity of the topic of rosacea seems to have waxed and waned over the years. This year there are mentions in keynote and symposium sessions for rosacea. It doesn’t seem like rosacea will have much of […]
6. NeoStrata Facial Cleanser and Ultra Moisturizing Face Cream
Rosacea sufferers are always on the lookup for suitable cleansers and moisturizers. One of the pearls in finding relief from rosacea symptoms is that finding a supporting and gentle cleansing and moisturizing (and protective) regime is important. A recent paper by Dr. Patricia Farris, Skin Care Based on Science: Improving Outcomes in Rosacea, tells us […]
7. Mirvaso Gel Judged Safe and Efficacious Long Term
This just published paper, in the peer-reviewed Journal of Drugs in Dermatology, again asserts that Mirvaso is “efficacious and safe“ for daily use over 1 year. This study details a trial of 345 users over a year, whilst the Mirvaso Prescribing Information quotes results from 276 users over 1 year. The previously published long term […]
