Rosacea News November 2009

Rosacea News November 2009

1. NY Derm likes Finacea instead of Retin-A

In an ELLE Magazine December 2009 interview, New York Dermatologist Macrene Alexiades-Armenakas, MD, PhD tells us that she has rosacea. A respected and published dermatologist, Dr. Alexiades-Armenakas says that she is one of the …

2. Promiseb even better than Desonide 0.05%

Promiseb Topical Cream has been found to be as effective as desonide cream 0.05% when treating facial dermatitis. This is an exciting finding, especially if the results can be replicated at large in the rosacea / seborrheic dermatitis community. …

3. What is this mysterious Nycomed 0444 Gel ?

The Clinical Trials register has listed a just completed trial for something cryptically called 0444 Gel. The Gel is targeted for the papules and pustules of rosacea. Apparently the study started in January 2008 and has just been completed. Study of 0444 Gel in the Treatment of Inflammatory Lesions of Rosacea Sponsor: Nycomed US Inc …

4. Accutane dose of 22mg a day works best: EADV

A summary from a the recent 18th Congress of the European Academy of Dermatology and Venereology has presented some findings relating to the most effect dosage of accutane to treat rosacea. Accutane (Isotretinoin) has been successfully prescribed in …

5. Vitamin K Oxide good for purpleness after PDL

A recently published paper is proposing the use of Vitamin K Oxide (Phytonadione Epoxide Hexane) as a treatment to accelerate the recovery from the redness and purple lesions following Pulsed Dye Laser. A previous study in 1994 also found that Vitamin K cream reduced the severity of post PDL purpura. Whilst the redness and indeed purpleness that Pulsed Dye Laser treatments can …

6. DER45-EV Gel from Sol-Gel files for IND

News today that Sol-Gel Technologies has filed for Investigational New Drug for a product they are calling DED45-EV. This topical gel is targeted as a treatment for rosacea.

There doesn’t seem to be other copies of this release, or related information so this could just be a pure PR exercise.

7. Treating Rosacea with Infrared Light: Patent

A newly filed patent contains a proposed rosacea treatment using small bands of infrared radiation between 790nm and 900nm with a power between 1 and 100 mW/cm^2. The unit proposed could be a LED device, used from twice a day to every 10 days. An energy density between 3 and 180 Joules/cm^2 is proposed.

Book Review: Rosacea: Diagnosis and Management, Frank C. Powell

Professor Frank Powell has created something quite valuable for rosacea sufferers and their physicians, an authorative and approachable medical text.

Author: Frank C. Powell
Review Date: December 2009
Available at Amazon.com

READ The full book review here:

Rosacea Diagnosis and Management.

Conclusion

This book gets off to an excellent start because the author is a genuine rosacea expert who is widely recognised. Professor Powell’s book is the sort of text that will see the understanding of rosacea symptoms, diagnosis and treatment increase world wide.

This book is by and far the best book on rosacea that you can get your hands on.

You can purchase the book at Amazon.com: Rosacea Diagnosis and Management.

See Also: other Rosacea Book Reviews

Rosacea News October 2009

Rosacea News October 2009

1. Oracea wins award for cute marketing

I can’t say that I know how much industry weight is carried by the publication Medical Marketing & Media, but they have awarded Galderma the Gold Award for `Best Individual Product Advertisement in Consumer Press’ for their …

2. Cetaphil adds UVA/UVB Defense SPF 50

Galderma announced in February a new SPF 50 Facial Sunscreen called Cetaphil UVA/UVB Defense SPF 50. Actually Galderma is not promoting this product as a sunscreen, but as a facial moisturizer. Said to be non-greasy and ..

3. Claim your Rosacea Community Blog Now !

Always wanted to have a blog or little corner of the internet you could call your own ? Well now you can. Every registered member of the Rosacea Support Community can have their very own blog area.

So please feel free to start your own Rosacea Community Blog.
Why would I want one of those ?
Your own blog will allow you post your thoughts, ideas, ..

4. IPL good for dry eyes too

WSOC-TV Charlotte, Carolina is syndicating a story about using IPL to successfully treat dry eye. Dr. Coad details how he is using IPL to treat this eye condition that is sometimes also found in ocular rosacea sufferers. Dr. Mannis in his interview for the RSRP had this to say about IPL and ocular rosacea. Q: Do you think ..

5. Topical Oxygen being trialled for sun damaged skin

A trial seeking participants interested in being treated with topically disolved oxygen (TDO) has been posted to clinicaltrials.gov. Aria Aesthetics is listed as supplying the `Aria Regimens’ in 0.5%, and 0.25%. As the trial is double blind and placebo controlled, a third group will receive no TDO during their treatments. Zoe Draelos MD is listed as a contact for the trial. Dr. Draelos ..

6. Clarisonic now available in the UK

The Daily Mail has published an article reviewing the Clarisonic in their Femail Beauty section. This article is no doubt motivated by the Clarisonic recently being launched in the UK (available exclusively via Space NK). The `oversized electric toothbrush’ is ..

7. Sansrosa starts strength tests, approaches final hurdle

In an encouraging sign that Sansrosa is slowly but surely progressing towards FDA approval, the clinicaltrials.gov register lists Galderma recruiting for a dose-finding trial for a product code named CD07805/47. The aim of this trial is show which strength is the most suitable for general use. Trial participants will be using one of 4 different strengths: 0.07%, 0.18%, %0.50 or effectively %0 contained ..

8. NRS research results explained

The NRS has just posted an easy-to-read summary of recent NRS funded research results. The update mentions the `Gallo Research’ and describes it ; “Dr. Richard Gallo at the University of California-San Diego found a consistently aberrant innate immune response in individuals with rosacea to environmental and emotional triggers.” Spin-off research related to type I interferon, plasmacytoid dendritic cells and enzyme involvement ..

9. Tetracyclines and Rosacea: what we already knew

Reading this just published abstract highlights for me just how slowly indeed research moves along. These recently proposed methods of action of tetracyclines seem to embody far from ground breaking research. We learnt in 2007 that tetracyclines have anti-inflammatory actions:  “Tetracyclines are known to exhibit multiple significant anti-inflammatory actions … the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation.

Rosacea News August/September 2009

Rosacea News August 2009

1. water soluble sunscreen anyone ?

An interesting looking patent application proposing a water based sunscreen for rosacea sufferers has surfaced at the USPTO. Many rosacea sufferers will know the trauma of finding a sunscreen that is gentle enough to not cause a bad reaction and effective enough to protect from the harm of the sun. For me the sun has always been my worst trigger. Certainly physical sunscreens …

2. so does acupuncture work, or not ?

For me acupuncture has always been part of some kind of ancient mythology. Humans are controlled by a brain that has complex neurological pathways to all corners of their bodies. Can inserting fine needles in to the so-called meridians along energy …

3. Epsom salts or Milk of Magnesia actually works ?

A few newspapers have picked up this Question & Answer article where rosacea sufferers are encouraged to try Epsom salts (magnesium sulfate) or Milk of Magnesia on their skin.

One can imagine that a bath with Epsom salts would be relaxing, but …

4. Sebclair launches as Promiseb Cream

I was alerted to the launch of a product called Promiseb by a comment left on the Sebclair for Seborrheic Dermatitis post. Since then the news web sites are also covering the press release. Promiseb (probably pronounced Promi-seb) is launching in the U.S. via Promius Pharma, after being licensed from Sinclair Pharma in 2007….

Rosacea News September 2009

1. Oracea worth $104m a year, good news for Sansrosa

According to a press release via Reuters, sales of Oracea were approximately $104 million for the twelve-month period ending July 2009. This figure is up almost 200% from the previously reported sales of $52.5 million in …

2. Impax Laboratories joins the generic Oracea battle

September 21st, 2009, by Digital Davo | oracea, patents | Edit

In a further confirmation that the low dose doxycycline market is a becoming a fighting ground, a recent press release states that Impax Laboratories has filed “Abbreviated New Drug Application ("ANDA") containing a paragraph IV certification for a generic version of ORACEA with the U.S. Food & Drug Administration ("FDA").” This is a challenge to the patents held by Galderma, relating …

3. PSF reduces the pain of Pulsed Dye Laser

This just published abstract from Lasers in Medical Science, shows that the extreme pain associated with pulsed dye laser, when used to treat port wine stains, can be relieved by using Pneumatic Skin Flattening (PSF). Pneumatic Skin Flattening uses a vacuum to compress the skin underneath the area being treated. Blood is eliminated from the treatment area. The technique is said …

4. FDA gets tough with Aczone

The FDA has issued a warning letter to Allergan, the makers of Aczone for overstating the efficacy of Aczone and also for understating the possible side effects. In a sign that the FDA is watching carefully the claims that vendors use when advertising their products, the warning letter calls out a journal advertisement for Aczone as violating the Federal Food, Drug, and Cosmetic Act. …

Rosacea News August 2009

Rosacea News August 2009

1. water soluble sunscreen anyone ?

An interesting looking patent application proposing a water based sunscreen for rosacea sufferers has surfaced at the USPTO. Many rosacea sufferers will know the trauma of finding a sunscreen that is gentle enough to not cause a bad reaction and effective enough to protect from the harm of the sun. For me the sun has always been my worst trigger. Certainly physical sunscreens …

2. so does acupuncture work, or not ?

For me acupuncture has always been part of some kind of ancient mythology. Humans are controlled by a brain that has complex neurological pathways to all corners of their bodies. Can inserting fine needles in to the so-called meridians along energy …

3. Epsom salts or Milk of Magnesia actually works ?

A few newspapers have picked up this Question & Answer article where rosacea sufferers are encouraged to try Epsom salts (magnesium sulfate) or Milk of Magnesia on their skin.

One can imagine that a bath with Epsom salts would be relaxing, but …

4. Sebclair launches as Promiseb Cream

I was alerted to the launch of a product called Promiseb by a comment left on the Sebclair for Seborrheic Dermatitis post. Since then the news web sites are also covering the press release.

Rosacea News July 2009

Rosacea News July 2009

1. Doxium being trialled as Pulsed Dye Laser adjunct

A new trial is recruiting participants to evaluate the use of calcium dobelisate as a combination therapy, along with Pulse Dye Laser to treat the erythema, flushing and telangectasia associated with erythematotelangietatic rosacea. We know from rosacea and doxium that “Calcium dobesilate is a vasoactive drug with presumed effects on endothelial integrity, capillary permeability and blood viscosity.” Clinical Trial …

2. Calling all Rosacea Researchers: get your grants now !

The National Rosacea Society is calling for grant applications for their 2010 allocation. Good to see that they want an emphasis on research into the cause rosacea. From New Grants Available Monday, July 27, 2009 New grants are available from the National Rosacea Society (NRS) to support research on potential causes and other …

3. Abstracts: Elidel, Bacteria & Ocular prevalence

The following abstracts don’t deserve a Rosacea News item on their own, but are interesting enough to give a mention here in this Abstract Roundup. Elidel no better than Metrogel for lumps and bumps of rosacea. A comparison of metronidazole 1% cream and pimecrolimus 1% cream in the treatment of patients with papulopustular rosacea: a randomized open-label clinical trial. Clin Exp Dermatol. 2009 …

4. Sol-Gel Trialling Benzoyl Peroxide (DER 45 EV) for Rosacea ?

An intriguing Clinical Trial has been listed on the ClinicalTrials.gov web site. The product know only as DER 45 EV Gel (in strengths of 1% and 5%) has been listed in a dose-range trial for the papules and pustules of rosacea. Clinical Trial NCT00940992, A Dose-Range of DER 45-EV in Treatment of Rosacea (SGT-EBPO1-09) …

5. we’ve all been exposed to demodex bacteria proteins ?

An article published today in the Irish Times takes one more step in the direction of showing an association between demodex mites and rosacea. Readers of Rosacea News will know that a lot of research has tried to find a causative link between the presence of demodex mites and rosacea symptoms. Some progress towards a link between the two was …

6. acupuncture, yoga, hat and moisturiser says Daily Mail

We are seeing more and more newspaper health and beauty articles that relate to rosacea. Today the UK’s MailOnline has an intriguingly titled article – How waggling my feet has helped my red face. To save you …

7. accutane and drinking alcohol – no problem, apparently

This just published abstract is suggesting that it appears to be safe to consume alcohol while taking accutane. Whilst the Accutane Prescribing Information does not prohibit the consumption of alcohol, it does suggest that alcohol …

8. CeraVe Hydrating Cleanser and CeraVe Moisturizing Lotion User Reviews

Recently the manufacturers of Finacea, Intendis, and Coria Laboratories, have begun promoting a new combination package it is calling Finacea plus. This package encourages rosacea sufferers to combine a tube of Finacea with CeraVe Hydrating …

9. Restasis (cyclosporine) as ocular rosacea treatment

It is good to see more published research backing topical cyclosporine (Restasis, Allergan) as a treatment for ocular rosacea. Restasis (cyclosporine ophthalmic emulsion 0.05%) has been shown to increase tear production and improve the quality of naturally produced tears and is …

Rosadyn Vasculokinetic and Skin Health Support

The Rosadyn site is full of scientific terminology.

Addresses all symptoms of Rosacea: Facial Redness and flushing skin inflammation and sensitivity inflammatory bumps and breakouts.

Advanced non-prescription oral nutraceutical for vascular, ocular and skin support

Targets the root precursors of facial redness, inflammation and flushing.

Developed by Dr. Geoffrey Nase PhD., Rosacea Specialist and Researcher.

Further claims about Rosadyn: advanced pharmaceutical-grade nutraceutical, vasculokinetic, Absorption Enhancement Blend, Hypothalamus Support, Hypothalamic overdrive.

Rosacea News June 2009

Rosacea News June 2009

1. doryx + applesauce, for those who can’t swallow tablets

If you have trouble swallowing tablets, here is an official FDA sanctioned tip. Open the tablet and sprinkle the delayed release pellets on to a spoonful of applesauce. This is a good option for anyone who finds swallowing the …

2. NYTimes says no natural remedies for rosacea

The New York Times has an article today keenly titled Natural Remedies for Rosacea?. The question is one that many rosacea sufferer seek answered – are there any effective treatments for rosacea that don’t include the use of antibiotics or prescription potions and lotions ? The answer comes from one of the premier rosacea experts – Dr. Frank C. Powell. Here is an extract …

3. Favourite Over The Counter treatments

Do you have a favourite over the counter treatment for your rosacea ? Depending on your health insurance and access to doctors and pharmacies, prescription treatments are out of the reach of many rosacea sufferers. So what can you try as a rosacea treatment that is easy to source, cheap and …

4. Vita-Oil Release Next Week. Tinted ZincO in July

Here is an announcement from RosaceaCare: “Earlier this year, we announced that four important and popular rosacea products that had been unavailable for many months would thereafter, by special arrangement with the originator, be manufactured and distributed by the Rosacea Care Company. We are pleased to tell you that the first of these, the much-loved Vita-Oil, will be released and ready to ship this …

5. Is Oracea different to 50mg doxycycline ?

I came across the following graph in a recent presentation at the recent AAD meeting and figured it was interesting enough to highlight it here. The following graph, sourced from Collagenex (who sell Oracea), shows the blood plasma concentration of doxycycline after taking Oracea compared to 50mg once a day of generic doxycycline. The horizontal axis stretches out to 24 hours post dosage. …

6. Doxium (calcium dobesilate) trialists wanted

Thanks to a comment from Sophie on the post rosacea and doxium (calcium dobesilate) we know that Dr. Cuevas who is responsible for several papers on Dobesilate, is accepting people to try it as a treatment for rosacea. Thanks for the info Sophie.

7. Green Tea helps after IPL

This just published paper is suggesting that the topical application of polyphenol antioxidants (aka green tea) post IPL treatment resulted in more hydrated skin and reduced oxidative degradation of skin lipids. The authors suggest that this will enhance the effects of the IPL therapy.