Acne Rosacea

Wednesday, October 09, 2013

Mirvaso to be a $100 million drug for Galderma

A revealing interview with the Galderma USA President Francois Fournier has just been published by the Dallas Fort Worth Healthcare Daily.

Wednesday, October 02, 2013

Rosacea News September 2013

1. Mirvaso User Reviews

Written by David Pascoe on September 26, 2013 with 3 Comments

Mirvaso is so new that only a few rosacea sufferers have been able to try it. What are your chances of having a bad reaction ? How are users in the real world faring, and will the general population see the same level of benefits as the large number of Phase III trialists ? Well […]

2. Mirvaso Gel Coupon (Cost Reduction Card) now available

Written by David Pascoe on September 24, 2013 with 0 Comments

As is the case for many of the prescriptions targeted at rosacea, the manufacturers of Mirvaso have made available a Mirvaso Coupon program. Galderma calls their Mirvaso campaign the Mirvaso Cost Reduction Card. The tagline for the promotion is “Eligible insured patients MAY pay no more than $50 for each Mirvaso Topical Gel prescription”. […]

3. American Acne & Rosacea Society, too close to Big Pharma ?

Written by David Pascoe on September 20, 2013 with 0 Comments

A really interesting post over at medpage TODAY is asking just what is the American Acne & Rosacea Society is up to, and asking the question are they too close to the bigPharma that they are funded by. We first learned of the existence of the AARS in 2006. Whilst it was puzzling as to […]

4. Mirvaso Patents to prohibit Generic Mirvaso

Written by David Pascoe on September 18, 2013 with 0 Comments

Galderma is claiming that the following patents protect their recently FDA Approved Brimonidine Gel known as Mirvaso. These patents are quoted in the Mirvaso Prescribing Information thus forming a public statement by Galderma to any would be competitors. Note one patent is for using Mirvaso to treat the broken blood vessels of rosacea (telangiectasis). This […]

5. North East US has the most Rosacea Sufferers

Written by David Pascoe on September 7, 2013 with 0 Comments

An interesting graph published on the NRS Blog shows that there is a high concentration of rosacea sufferers in the North East of the USA. The graph shows the residents of New England have the highest incidence of rosacea in the country. Puts a different spin on red states vs. blue states eh? The NRS […]

6. Treating Redness with Crolom (cromolyn sodium ophthalmic solution, 4%)

Written by David Pascoe on September 5, 2013 with 0 Comments

A trial by a Dr. Di Nardo using mice has found that cromolyn sodium ophthalmic solution 4% is able to reduce skin redness. This small trial, which will be double blinded seeks to see whether the effect can be replicated in humans. A total of 10 patients will be given either the saline vehicle or […]

7. How much do Rosacea Prescriptions Really Cost?

Written by David Pascoe on September 3, 2013 with 12 Comments

You don’t have to read the online rosacea forums for very long to see the outrage at how much rosacea sufferers, especially in the US, pay for Rosacea Prescriptions. If you want to try Metrogel 1%, Oracea or Finacea what might you expect to pay? The answer is actually not straight forward. A lot will […]

8. Will I have a Bad Reaction to Mirvaso?

Written by David Pascoe on September 2, 2013 with 0 Comments

Now that Mirvaso has been officially approved by the FDA, the final clinical trial results quoted to the FDA have become available. The Mirvaso Prescribing Information contains some statistics relating to the number and type of adverse reactions that occurred during the clinical trials. So if you are prescribed Mirvaso, what are your chances that […]

Wednesday, September 18, 2013

Rosacea News April 2003

Xifaxan and SIBO Treatment of Rosacea

Another paper investigating the link between Small Intestine Bacteria Overgrowth and rosacea symptoms has recently been published. Many of the results in this 2013 letter to the editor of JAAD confirm early discoveries from the 2008 paper from Clin Gastroenterol Hepatol. The earlier paper concluded that ; This study demonstrated that rosacea patients have a […]

Wanted SF: Asian Women with Redness for Translucent Treatment Powder

Biometrix are looking for trial participants in San Francisco. This trial is looking for Asian Women with facial redness, interested in trying a `mineral treatment pressed powder’. The powder is said to visibly reduce redness on application. See below for more details. Biometrix conduct possibly relevant trials each month, so you are in San Francisco […]

PreCision Dermatology Trialling PDI-320

A slightly obscure clinical trial has recently listed, related to treating the lesions and facial blood vessels of rosacea. The drug mentioned is PDI-320, and the party conducting the trial is Precision Dermatology. What is PDI-320? If you look closely at the exclusion criteria, you see that participants are not allowed to have “previously failed […]

Sansrosa and Afrin Updates from Dr. Fowler & Dr. Webster

Skin and Allergy News is running an article dated this week based on some informal comments from Dr. Joseph F. Fowler Jr. and Dr. Guy W. Webster given recently at the Hawaii Dermatology Seminar sponsored by the Global Academy for Medical Education/Skin Disease Education Foundation (SDEF). These comments relate to two of the hottest topics […]

Indian Pharma may allow Generic Oracea

There is always a lot going on in the world of BigPharma. A recent court case in India suggests that the Indian Government will allow local manufacturers to produce generic versions of in-patent drugs that are simple derivatives of existing drugs. India’s law restricts pharmaceutical companies from obtaining new patents for small modifications to existing […]

Rosacea News May/June 2013

Proving Sansrosa works as well as users think

A slightly unusual trial has surfaced at ClinicalTrials. The Phase 3 trial for Sansrosa seeks to prove that patients’ satisfaction with Sansrosa matches being treated with the active gel. In short, the trial wants to prove that any improvement in facial redness perceived by the trial participant can be shown to be because of Sansrosa. […]

New Demodex Treatment: MooGoo Demodectic Rosacea Powder

Came across an interesting looking new product from MooGoo – Demodectic Rosacea Powder, that appears to be available to order. The product is an innovative approach to try to eliminate demodex mites by making the surface of the skin an environment where the mites cannot survive. If this demodex-hostile environment can indeed be achieved whilst […]

Acne Bacteria causes Chronic Lower Back Pain

Seems like a solid result, showing that in patients with `slipped discs’ (prolapsed is a better term) can benefit from antibiotic therapy to eliminate Propionibacterium acnes. This bacteria is known to play a role in acne and is now believed to have a role in the inflammation of chronic lower back pain. Participants in these […]

Patent: Rapamycin / Sirolimus to treat Telangiectasia

There are very few existing rosacea treatments for the broken blood vessels and general red face of rosacea. Historically laser and IPL are the only proven treatments for this rosacea subtype. In the last couple of years rosacea sufferers have been encouraged by the development of 2 new drugs that could help treat these symptoms […]

Solodyn with and without Finacea

A recent study has highlighted the benefits of the combination therapy of Solodyn and Finacea. Solodyn is one of the lesser known systemic rosacea treatments. What is Solodyn? Solodyn is an extended-release, low dosage of Minocycline, a member of the tetracycline family. Solodyn is available in 8 strengths. Yes that is right you can get […]

Rosacea News July 2013

1. Bionect improves Rosacea Symptoms

A recent paper in the Journal of Drugs in Dermatology suggests that Bionect may be helpful for the symptoms of rosacea. The study found that after 4 weeks the burning or stinging and dryness of rosacea was much improved, while papules and redness were also improved. What is Bionect? Bionect is a prescription only cream, […]

2. Sansrosa looks to be marketed as Mirvaso

Thanks to a post from Barbara, we have learnt that a member of a German support forum for rosacea, that Galderma may be planning to market Sansrosa as Mirvaso. It is pretty brief but here is what we know so far. Re: New form of therapy! by Mary »Wednesday 27 July 2013, 08:56 Hello, I […]

3. SIG990 Gains IND Status for Rosacea Redness and Lesions

Previously known as Signum Biosciences, Signum Dermalogix has announced today that the FDA has granted them IND Status for the Isoprenylcysteine Analog known as SIG990. Investigational New Drug status means that the FDA believes that the molecule is safe enough to commence clinical trials. This means that SIG990 is moving into Phase I of is […]

4. Promiseb now available as Scalp Wash

The nonsteroidal prescription Promiseb is now available as a Scalp Wash. Available only as part of `Promiseb Complete’, Promiseb Plus Scalp Wash is said to have “earned favorable ratings from patients for Helping with the appearance of dandruff and scalp redness” What is Promiseb? Promiseb Cream is a FDA-cleared medical device and has no active […]

Rosacea News August 2013

1. Mirvaso Before and After Pictures

What sort of benefit might you expect from using Mirvaso to treat your rosacea redness? Well, Galderma has made available some publicity photographs that show before and after photographs from the Mirvaso Clinical Trials Quite impressive, don’t you think ? Related Articles Mirvaso (Sansrosa, Brimonidine) Approved for Rosacea Redness Mirvaso Ingredients […]

2. Skinova helps rosacea with Ultrasound Skin Treatments at home

A recently published paper introduces us to a new form of at-home therapy based on high frequency ultrasound. The Skinova treatment using sound waves at a very high frequency of 10 MHz. This allows treatments to a depth of around 0.3cm. At this depth we are told that “the effect is mainly concentrated on the […]

3. Mirvaso Ingredients

The just approved Mirvaso is a milestone in the long development and approval process. Rosacea sufferers have watched this drug since as early as 2004 when patents started emerging. Now that Mirvaso has been officially approved by the FDA more information about the final formulation has emerged. From the Mirvaso Prescribing Information we can see […]

4. Mirvaso Ingredients

5. Mirvaso (Sansrosa, Brimonidine) Approved for Rosacea Redness

News today that Galderma has succeeded in gaining FDA Approval for Mirvaso – the brand name chosen for the product that during development was known as Sansrosa, CD07805/47 and Col-118. The Brimonidine Tartrate 0.33% Topical Gel is expected to be available as soon as next month. Great news that approval has been granted after so […]

6. Step backwards for Generic Oracea. Invalid patents are back

For those following the saga of the possible availability of Generic Oracea in the future, another twist today. Two of the patents that were previously ruled invalid and thus unable to protect Galderma’s product, have now been ruled no longer invalid. This legal ruling will no doubt embolden Galderma that their profitable product Oracea can […]

7. Patent: Combining Sansrosa and Finacea

Galderma is staking out its claim on potential rosacea topicals with another patent being published. This patent details potential topicals that are combinations of the active ingredients in Sansrosa and Finacea, namely Brimonidine Tartrate and Azelaic Acid. The touted benefits from combining the two actives is a reduction in rebound redness and a greater tolerance […]

8. Generic Oracea one step closer, Lupin gets Tentative FDA Approval

News today that Lupin has been granted tentative approval by the FDA to product a generic version of Oracea. We learn in 2010 that Lupin had filed an abbreviated new drug application to make generic Oracea. Lupin Pharmaceuticals, based in Mumbai India, is a company specialising in the production of generic medicines. It has been […]

Monday, August 26, 2013

Sansrosa is now known as Mirvaso

Sansrosa is dead, long live the king, now known as Mirvaso.

News today that Galderma has succeeded in gaining FDA Approval for Mirvaso – the brand name chosen for the product that during development was known as Sansrosa, CD07805/47 and Col-118.

It is no longer called Sansrosa – it it called MIRVASO !!

The Brimonidine Tartrate 0.33% Topical Gel is expected to be available as soon as next month.

Mirvaso Approved for Rosacea Redness

Breaking !

News today that Galderma has succeeded in gaining FDA Approval for Mirvaso – the brand name chosen for the product that during development was known as Sansrosa, CD07805/47 and Col-118.

The Brimonidine Tartrate 0.33% Topical Gel is expected to be available as soon as next month.

Monday, January 21, 2013

Your Best Rosacea Home Remedy

I have never really tried a home remedy. Perhaps you have ?

Calamine Lotion
Epsom Salts (Milk of Magnesia)
How about Red Light Therapy at Home

It is possible to come up with a rosacea home remedy. Rosacea relief in your kitchen cupboard ? Sounds too good to be true …

How do you like, get rosacea

Well it is one of the first questions you often as - How Do You Get Rosacea? It is understandable that you think you did something wrong to bring on rosacea. Well it isn’t that simple. It is possible that you used something that has brought on the last stage that revealed as rosacea, but mostly it is just that genetics and environment conspire together.

For more info: How Do You Get Rosacea?

Wednesday, January 16, 2013

Rosacea Cream

What is the best Rosacea Cream?

If you are new to rosacea you might be hoping that rosacea will go away with just a quick treatment with some cream from the doctor.

Read on for more information: What is the best Rosacea Cream?

Rosacea News September 2012

Scenesse Shows Promise for Acne

Scenesse has been tested as a treatment for acne, and the results are looking good. Before you get too excited, though, lets get all the disclaimers out of the way right up front … Clinuvel, the developers of Scenesse are not currently pursuing Scenesse as a treatment for acne The study presented was very small, …

All You Ever Wanted to Know About Demodex Mites

If you search for demodex using Google’s Scholar search, you will find over 8,000 papers that mention them.

Further if you search for demodex and rosacea you will get nearly 2,000 results. So there has been plenty of research into the topic.

Whilst a clear causal link between the …

The National Rosacea Society is 20 Years Old

A recent blog posting from the NRS has mentioned that this month the National Rosacea Society is 20 years old. NRS Celebrates 20 Years Thursday, September 6, 2012 …

DT: Sansrosa 0.5% Better than 0.18% Twice a Day

Dermatology Times today has an article that confirms some insights into the recent Phase II study into the safety and efficacy of different strengths of the Sansrosa Gel. The article adds some personal insights into the trial from the principal investigator, Dr. Joseph Fowler MD. This is not the most recent news as Rosacea News highlighted some of these Phase II results back in …

Redless Specific Serum from Integral Dermo Correction

A just published paper eludes to a new redness reducing cosmeceutical. The product is referred to as 100RXED2025, but it looks likely that the …

Rosacea News August 2012

1. Epigallocatechin Gallate (EGCg) from Green Tea Shrinks Skin Cancers

An article today in the Daily Mail highlights some research into the actions of an extract from Green Tea on skin cancer tumours. Interestingly the same benefit would not be …

2. Rossoseq for the Redness of Rosacea

A new product known as Rossoseq is to be trialled as a treatment for the redness of rosacea. The trial is sponsored by a company calling itself PBB Entrepreneur Ltd. and seems to be based in Germany. 60 people are to be enrolled in the trial, which is due to be completed by October 2012. The trial sites are 4 cities in Germany: Bochum, Duelman, …

3. Comparing Sansrosa to Finacea for Redness

Galderma are surely confirming that the development of Sansrosa 0.5% Gel (CD07805/47) is nearing completion, with the posting of a proposed comparison trial with Finacea. The trial NCT01659853 will compare how effective Sansrosa is compared …

4. Evening Standard: Avoiding Facial Redness

The London Evening Standard has a Health & Beauty article today highlightinghow to relieve a red face. Dispelling the myth of a peaches and cream complexion, but staying with a fruit similie by calling it `Strawberries’ & Cream, Leah Hardy highlights the following possible ways to relieve a red face; La Roche Posay Anthelios Extreme …

5. T4O Pads (Terpinen-4-ol) for Ocular Demodex

An interesting new product that contains the main active ingredient from Tea Tree Oil has emerged in a new clinical trial listing.

The trial titled Demodex Blepharitis Treatment Study, is sponsored by a company called Tissue Tech Inc. …

Rosacea News July 2012

Metronidazole Gel 2% Good for Acne

Acne seems to have a lot of available treatments. Certainly compared to rosacea, acne has a bigger array of possible treatments that have been proven to be viable treatments. One of the interesting things about rosacea is that even though it can look like acne for some, generally it cannot be treated by otherwise helpful acne treatments. Rosacea sufferers with sensitive skin may well …

Just Diagnosed: JAMA Rosacea Patient Page

The Journal of the American Medical Association have released a free Rosacea Patient Page in their June 2012 edition. The JAMA have made this page available for free. This may prove useful for those who are wondering if they have rosacea and those looking for a confirmation of their symptoms. The illustration shows the full gamut of rosacea symptoms: dry, red, irritated eyes, …

Ocular Rosacea Diagnostic Test One Step Closer

In the last couple of years research has emerged that could lead to a diagnostic test for ocular rosacea. There is currently no physical test that can definitively …

More Demodex Dreaming: Mites are the Chicken?

The NRS recently highlighted a paper speculating that demodex mites are the missing link in papulopustular rosacea, or as they characterised the mites are the “chicken coming first …

Aczone Fails to Impress for Rosacea

We don’t often get to see the actual results from clinical trials. Companies are happy to receive publicity for their research and development programs, especially if a new product looks promising. If things don’t go we during clinical trials, though, it …

Using a Hair Dryer to Pre-Flush before Pulse Dye Laser Treatment

This paper is promoting the use of a pre-flush to improve the outcome of Pulse Dye Laser (PDL)Rosacea Treatments. The authors suggest that by increasing the number of …

Novartis Must Drop Fougera’s Generic Metrogel

In May this year we learnt that Novartis would be buying Fougera Pharmaceuticals . One of the products that would come over to Novartis through this deal would be …

Does Finacea improve ND: YAG Laser Treatments?

Intendis, the makers of Finacea are to trial the combination of ND:Yag laser treatment with and without the addition of Finacea during treatment. As the study will be a spilt face trial, researchers will be able to show that the addition of Finacea does, or does not make a difference to the outcome of the laser treatment. The study wills assess acneiform lesions, …

Combine Brimonidine and Oxymetazoline, Why Not?

There is plenty of interest in two molecules that are in development to treat the redness and flushing of rosacea. Both Brimonidine and Oxymetazoline have been the subject of a lot of research and development efforts in the last 3-4 years. One of the ways that rosacea sufferers learn about progress in the state of the art of rosacea research such as new …

Sunday, October 07, 2012

Topical Ivermectin

Rosacea and Sklice

Sklice is a new topical ivermectin 0.5% that is approved for the use of the scalp and hair for head lice.

Monday, August 20, 2012

Rosacea Support Links

Wednesday, July 18, 2012

Rosacea News June 2012

1. Treating Rosacea with Collagen (Matricol)

Martricol, which is freeze dried sheets of collagen, is another example of a hopeful rosacea treatment emerging in a patent application. This time a health care company in …

2. “MetroFoam” is Better than Metrogel

OK the title is a bit of a stretch as currently there is no such product as Metrofoam, but keep reading to see where I’m coming from. Last year a patent surfaced, owned by Galderma, claiming rights to a “stable, metronidazole-based oil-in-water emulsion expandable into a topically applicable foam having a firm, creamy and light consistency” and is claimed to have improved release-penetration …

3. Demodex Bacteria Protein Response Isolated

Hot on the heels of a paper detailing the fact that demodex bacteria-based proteins inhibit corneal wound recovery, is this paper consolidating a direct relationship between an immune response and facial and ocular rosacea.

Recent research from 2007 has isolated 2 proteins from the bacteria from Bacillus oleronius, that …

4. Counting Demodex Mites with a Confocal Laser Microscope

This paper describes a new way of counting facial demodex mites. A type of microscope called a Confocal Laser Scanning Microscope was used to look for `roundish or lengthy cone-shaped structures’ on the skin, and these were …

5. Tanda Luxe (Red LEDs) for Facial Wrinkles and Cheek Rosacea

A clinical trial has been listed for the Tanda Luxe, a Red LED device that is to be used as a treatment for wrinkles and facial rosacea, especially on …

6. Wanted SF: Daily SPF15 Green Tint Corrector Trialists

I have been contacted by Yvonne Law from Biometrix, who are looking for volunteers in San Francisco who are interesting in trialing a new product from a well known cosmetic company. The product is a “facial SPF with green tint corrector to reduce facial redness”. The company says that this product is “now being researched for efficacy, safety in use, and advertising claim support." …

7. Allergan Developing Oxymetazoline (AGN-199201/V-101) Cream Formulations

A recently surfaced patent application shows that Allergan are continuing to protect their intellectual property around their proposed Oxymetazoline based facial redness treatment.

This patent application relates to the technology and inventions used to create a suitable cream formulation of oxymetazoline. It covers how …

8. Xeomin (Botulinum Toxin Type A) being Trialled as a Rosacea Treatment

The BOTOX relative Xeomin is to be trialled as a treatment on the cheeks of rosacea sufferers. We are not told in the trial description if the rosacea …

9. Elevated Proteins in The Skin of Ocular Rosacea Sufferers

The following abstract details some research that was undertake to characterise what is happening in ocular rosacea. There is currently no accepted diagnostic test for rosacea. Some History Rosacea News first highlighted a possible diagnostic test for ocular rosacea in late 2005. The article from the Journal of Proteome Research concluded that “The high abundance of oligosaccharides in the tear fluid of …

Sunday, June 10, 2012

Rosacea News May 2012

1. Why Has No One Found a Cure for Rosacea?

Why has no one found something even remotely close to a cure for rosacea ? Why do researchers admit that they can barely even describe the disease ? Well a clue emerges from a recent series of in depth, state of the art papers from the Journal of Investigative Dermatology Symposium Proceedings. In the introductory item title “Pathophysiology of Rosacea: Introduction”, Dr. Martin Steinhoff …

2. Scenesse Starts Phase III Trials for EPP in the US

News today that Scenesse has progressed another step towards wider approval with the commencement of Phase III Trials. About 100 people with the condition Erythropoietic Protoporphyria (EPP) will be double blinded to receive the Scenesse implant or placebo. …

3. Smokers Much Less Likely to get Rosacea

Yes you read correctly, some recent research conducted in the UK has found that smoking is associated with a substantially reduced risk of developing rosacea. The study …

4. How Much Would You Pay to Cure Your Rosacea?

Most published abstracts are a pretty dry read. This one is about as dry as they come. How about titling it “Rosacea Sufferers Willing To Pay Less than Vitiligo, …

5. Coblation with Saline and Radio Frequency Induced Plasma: Rhinophyma Miracle

The Daily Mail continues to show itself as the premier newspaper for rosacea related news stories. This last weekend the paper has a great …

6. Rosaliac AR Intense from La Roche-Posay

In 2010 La Roche Posay took the opportunity of the rosacea awareness month and their support of the National Rosacea Society to promote their product – Rosaliac UV Fortifying Anti-Redness Moisturizer with SPF 15.

7. Novartis Buys Fougera for $1.5B, gets Generic Metrogel

News today that the giant pharmaceutical company Novartis International is buying Fougera Pharmaceuticals.

Fougera is known to rosacea sufferers through the availability of generic metronidazole 0.75%. Fougera will brings its specialty in generics to Sandoz, the generics division of Novartis.

Sunday, April 29, 2012

Rosacea News January 2012

1. IPL Burns from Perth Home Operator

An article in this Weekend’s West Australian highlighting the dangers of IPL Treatments from untrained operators. This article is a reminder of the dangers of IPL in the wrong hands. Other warnings are, sadly, easy to find. Finding the right practitioner to treat you with IPL is not an easy task. This is a real dilemma for rosacea sufferers as we …

2. Taro Readying for Generic Metrogel 1%

A recently posted clinical trial suggests that Taro Pharmaceuticals is readying to gain approval to market Generic Metrogel 1%. Currently Generic Metrogel is only available in 0.75% strength. Taro Pharmaceuticals in fact already markets a generic form of Metrogel – Metronidazole Gel USP, 0.75% When the patent covering Metrogel 0.75% expired, Galderma changed the formulation, increased the concentration of metronidazole to 1% …

3. Patents Expire for Liptor and Zyprexa, Oracea Small Fry

While us in the rosacea world might consider products that are expensive while they are covered by exclusive patents, we are small fry in the drug market at large.

Patents are due to shortly expire for Pfizer’s Liptor and Lilly’s Zyprexa. Lilly can expect a $3bn drop in revenue just from generic forms of Zyprexa becoming available. Pfizer is thought to have earned around $7.8bn from …

4. Metrogel 1% Pump; for those who don’t like a Tube?

Galderma have announced that Metrogel 1% will now be available in a 55gm Pump. Galderma are citing the benefits of a better looking dispenser, minimizing waste, easier compliance with prescribing instructions and “facilitating product handling”. Galderma received FDA …

5. 2011, The Year in Review

Happy New Year to everyone who reads Rosacea Support ! As we start 2012 lets look briefly at what was popular in the last year. …

Rosacea News February 2012

1. Treating Neurogenic Rosacea with ETS

Now that the collection of symptoms called Neurogenic Rosacea has become more widely known, new discussions can take place as, for example how to best treat it.

This recently published abstract details a patient who suffered debilitating facial redness and burning. The patient was treated with the invasive and possibly irreversible procedure Endoscopic Thoracic Sympathectomy. The patient had a good response to ETS.

2. Cyclosporin better than Artificial Tears for Ocular Rosacea

Skin and Allergy News has an article today highlighting the recent positive research into the usage of Cyclosporin as a treatment for Ocular Rosacea.

Dr. Harper mentions that she likes to include Oracea as an oral treatment for the worst of her ocular rosacea patients, but …

3. Get ready for Tinted Finacea

A recently surfaced patent assigned to Intendis suggests that we might soon see a Tinted Finacea reach the market.

According to the patent application, a tinted formulation of Finacea had improved anti-inflammatory effects compared to regular Finacea – “Surprisingly, it was found that there was a further marked reduction in cytokine release in the cultures treated with azelaic acid and titanium dioxide-coated potassium aluminium silicate 3%”.

4. Doxycycline can deactivate Cathelicidins

A recently published abstract from the house of Gallo suggests a clue as to how doxycycline might work in treating rosacea. The suggestion from this research is that doxycycline has a newly discovered mechanism of action whereby it is able to prevent the activation of cathelicidin.

Cathelicidin has been in the rosacea news since around 2002, gaining publicity because of the discoveries like the fact …

5. Maruho Acquires Cutanea Life Sciences

News this week that the Japanese company Maruho is to acquire Pennsylvania based Cutanea Life Sciences. Cutanea Life Sciences is developing Omiganan as a treatment for rosacea.
Maruho Co., Ltd. Acquires Cutanea Life Sciences, Inc.

6. Massive Rosacea Study (CD5024) Recruiting Underway

A large study looking at a treatment for the papules and pustules of rosacea is looking to recruit participants right across the US and Canada.

A web site just for this study has been created at www.pprstudy.com (Papulo – Pustular – Rosacea Study). On the site you can use your ZIP code to see if there is a study location close to you.