Rosacea News June 2010

Rosacea News June 2010

1. How many people suffer from Rosacea ?

One of the areas of research that attracts attention in the press and it also interesting to rosacea sufferers revolves around how many people have rosacea. The latest 2010 estimates from the NRS suggest that 16 million Americans suffer from rosacea, up from the last estimate of 14 million.

The incidence of rosacea is studied because there is a belief that the statistical analysis will …

2. Just how does Finacea work ?

I’m not sure that I have laid awake at night wondering about how exactly finacea does it’s thing, but as Rosacea News had a stab at Just how does metrogel work ? a while ago, an attempt at covering Finacea’s method of action is only fair.

It is interesting to consider how finacea works especially if that knowledge might lead to …

3. Vitamin D may help the Flu as well

Vitamin D continues to attract interest as does the list of ailments that are now associated with this nutrient. We know from previous studies that Vitamin D modulates the production of cytokines, thereby suppressing inflammation, but here we see that this has been linked not to rosacea, but viral infections such as the flu. Serum 25-Hydroxyvitamin D and the Incidence …

4. Finacea now available in Canada

Canadian rosacea sufferers have up until now been unable to officially use Finacea. Bayer HealthCare Pharmaceuticals have announced that Finacea is now available in Canada. Finally Canadians can get access to Finacea via prescription bringing them …

5. What rosacea topic do you most want to read about ?

If you could ask for a topic for an article on rosacea, what would you ask for ? I have been approached by someone who is contemplating writing an article that would be interesting for rosacea sufferers to read. This article could be published in a magazine or journal and depending on the topic could contain some useful research as well. So here …

6. Foamix to trial foaming topical minocycline

The prescription topical market for rosacea seems to be somewhat crowded. Sufferers have the choice of the metrogel family, finacea as well as the potential to try acne topicals such as retinoids. So far there hasn’t been a proven topical anti-biotic per se. Metrogel and Finacea have anti-inflammatory properties, but are not classified as anti-biotics.

Rosacea News May 2010

Rosacea News May 2010

1. Cetaphil RestoraDERM for extra dry skin and Eczema

Already available in Canada, Cetaphil will introduce a new line of products for dry sensitive skin in August in the US. The line is called RestoraDERM and is targeted at Eczema sufferers who struggle to maintain the natural moisture balance of their skin. For those rosacea sufferers who also …

2. Research Briefs: IPL, Laser and Stress

Here are brief mentions of recently published papers that look interesting to rosacea sufferers.

1. Intense pulsed light in the treatment of non-aesthetic facial and neck vascular lesions: report of 85 cases

IPL treatments were given 4-6 times 3 weeks apart. 35 rosacea `lesions’ were studied overall. The abstract links the results of rosacea and Poikiloderma of Civatte together, saying that the vast majority of lesions …

3. NRS on Beta Blockers and flushing

In the latest edition of Ask the Doctors, Dr. Jonathan Wilkin, chairman of the NRS medical advisory board answers the question `Do beta-blockers help reduce flushing from rosacea?’.

The answer is brief but I’m encouraged to see the NRS discussing further the possibility of using beta blockers for flushing in rosacea sufferers.
In severe cases, a beta-blocker may sometimes be prescribed to help reduce emotionally triggered flushing …

4. Atralin Gel (Tretinoin 0.05%) being trialled for the redness of Rosacea

The Clinical Trials Register is listing a new trial today for a topical retinoid, Atralin Gel 0.05% for the treatment of the redness and broken blood vessels of rosacea. Officially the trial will look at the redness, telangiectasia, …

5. SIG990 Excellent for Redness, several years away

In a recent email to Rosacea News, Dr. Eduardo Pérez, VP of Operations at Signum Biosciences has confirmed that SIG990 is undergoing preclinical safety/toxicology testing as required by the FDA before clinical trials can commence. You can see this confirmed at the company’s web site: Pharmaceutical Development Pipeline. Signum Biosciences has several molecules under development, SIG990 is their lead candidate for rosacea. …

6. Afamelanotide (Scenesse) now available in Italy

Clinuvel has announced today that Italy has pre-empted the approval of Afamelanotide by the FDA in the US by approving it for the treatment of erythropoietic protoporphyria (EPP).

7. An interview with Colin Dahl from Australian Sciences

Our first guest is Colin Dahl, Chief Scientist at Australian Sciences and the author of A Practical Understanding of Rosacea, Part 1: Heat Regulation and the Warm Room Flush Phenomenon that has been of great help to many rosacea sufferers. We hope you will find these interviews an interesting read.

Scenesse now available in Italy

Clinuvel has announced today that Italy has pre-empted the approval of Afamelanotide (Scenesse) by the FDA in the US by approving it for the treatment of erythropoietic protoporphyria (EPP).

Despite the relatively small number of participants in the Italian trial to treat EPP, and the small number of EPP sufferers thought to directly benefit from this therapy, the approval by Italian Medicines Agency (AIFA) is significant because it confirms Afamelanotide’s efficacy and safety and also that national medicine agencies are willing to rapidly approve afamelanotide.

Clinuvel have also announced that afamelanotide will be marketed under the brand name of Scenesse (pronounced “sen-esse”). From today onwards, Clinuvel will adopt SCENESSE in all references to the drug in its further global clinical development.

Related Articles

• Q&A with Clinuvel on Afamelanotide and Melanotan
• Photoprotection expertise from Clinuvel
• Afamelanotide (Clinuvel CUV1647) gets orphan drug status in the US

Scenesse now available in Italy

Clinuvel has announced today that Italy has pre-empted the approval of Afamelanotide by the FDA in the US by approving it for the treatment of erythropoietic protoporphyria (EPP).

Despite the relatively small number of participants in the Italian trial to treat EPP, and the small number of EPP sufferers thought to directly benefit from this therapy, the approval by Italian Medicines Agency (AIFA) is significant because it confirms Afamelanotide’s efficacy and safety and also that national medicine agencies are willing to rapidly approve afamelanotide.

Clinuvel have also announced that afamelanotide will be marketed under the brand name of Scenesse (pronounced “sen-esse”). From today onwards, Clinuvel will adopt SCENESSE in all references to the drug in its further global clinical development.

Related Articles

• Q&A with Clinuvel on Afamelanotide and Melanotan
• Photoprotection expertise from Clinuvel
• Afamelanotide (Clinuvel CUV1647) gets orphan drug status in the US

Rosacea News April 2010

Rosacea News April 2010

1. Gut Bacteria and Xifaxan get some press coverage

April 30th, 2010, by David Pascoe

The St. Louis-Dispatch has an article today exploring the link between the overgrowth of small intestinal bacteria and rosacea symptoms for some rosacea sufferers. New way to treat skin disorder By Cynthia Billhartz Gregorian, ST. LOUIS POST-DISPATCH, 04/29/2010 … Weinstock is not a dermatologist. He’s a founding partner …

2. Ocular symptoms match Demodex Bacteria reaction too

April 29th, 2010, by David Pascoe

This paper is one more small achievement using statistics to try to build a picture of how demodex mites might be involved with rosacea symptoms. We have learnt from recent research that rosacea sufferers are sensitive to 2 particular types of bacteria that have been isolated in demodex mites. This study further establishes that a reaction to the bacteria correlates to ocular …

3. Light Masque: a LED array from the future

April 27th, 2010, by David Pascoe

The Daily Mail has a recent article looking at a futuristic LED array that wraps around your whole face. Along with a brief review of the device, the author finds it hard to wrap their mind around the claimed …

4. NHS should stop funding Homeopathy: MPs

April 26th, 2010, by David Pascoe

A recent submission to the House of Commons Science and Technology Committee has said that using public money on the highly-diluted remedies of homeopathy could not be justified. The cross-party group said there was no evidence beyond a placebo effect, when a patient gets better because of …

5. NRS Announces 2010 Research Grants

April 23rd, 2010, by David Pascoe

The National Rosacea Society has announced a new round of grant funding. Three new studies have been given a grant as well as continuing the ongoing research of 3 studies. Research Grants Awarded Thursday, April 22, 2010 The National Rosacea Society (NRS) has awarded funding to three new studies and continues to fund three …

6. RRDi journal Issue 1 Review: an unfortunate mix

April 21st, 2010, by David Pascoe

The RRDi recently published the first issue of their journal. Rosacea News was given a pre-print version to review. Volume 1, Number 1 is 88 pages and is available for around $15. I was quietly hopeful that a publication `produced by volunteers and written by dermatologists, physicians, researchers and patients’ could be something worthwhile and progressive for the field of rosacea. Sadly my …

7. Accutane Dose 22mg a day compares well to low doses of Doxycycline

April 20th, 2010, by David Pascoe

A paper that Rosacea News previewed in November last year: Accutane dose of 22mg a day works best: EADV has now been published in the JDDG: Journal of German Society of Dermatology. As we learned from the …

8. Every cloud has a silver lining

April 18th, 2010, by E.L. Hodge

European rosaceans unable to fly right now might temper their frustration with the thought that the subtle atmospheric changes caused by the eruption of Eyjafjallajökull might just be helping their symptoms. The volcanic stuff being spewed into the air is rich in sulphurous materials. Sulphur, of course, is a well established rosacea topical. Now, you may be sure that this is no desperate effort …

9. Cure Your Rosacea: ebook review

April 16th, 2010, by David Pascoe

I was sent a copy of the ebook that is for sale at www.cureyourrosacea.com to review. Here are my thoughts on what the author says took 10 years to discover and write. I wasn’t that thrilled to see the web site that sells this ebook sporting a blue+yellow sunflower theme. The sunflower theme has branded rosacea-support.org for several years now and I …

10. Signum Biosciences developing SIG990 for Rosacea

April 15th, 2010, by David Pascoe

A company called Signum Biosciences is developing a new product to target rosacea. Based on a technology that they call G-protein Modulators, GPMs are said to “restore signalling imbalances in the cell”. A first generation product called Arazine is soon to become available and a second generation of products are to target rosacea, psoriasis and eczema.

According to Signum Bioscience’s Development Pipeline, SIG990 is in …

11. Placebo Treatments work even if you know they’re fake

April 14th, 2010, by David Pascoe

An interesting piece in the Australian media recently looking at whether treating patients knowingly with placebo treatments might actually offer some benefits. I have always been fascinated with the whole placebo effect. How exactly can our belief …

12. Inkjet that Sprays on Skin Cells for Burn Victims

April 12th, 2010, by David Pascoe

A press release via Reuters details a new and exciting alternative to skin grafts for burn victims. The method includes some stem cells which allows hair follicles and sebaceous glands to develop in the new layers of skin.

This development offers another possible avenue for rosacea treatments similar …

13. Face Transplant Recipient gets donor’s Rosacea

April 10th, 2010, by E.L. Hodge

As we all well know there are lots of things worse than rosacea. And, it turns out that one of the things worse than rosacea is having half a face. You see, James Maki who last year received a partial face transplant reports that, in spite of now being permanently red faced on account of the donor being a rosacean, he is very pleased …

14. Oracea and Metrogel FREE for low income no insurance

April 9th, 2010, by David Pascoe

Being prescription items, Oracea and Metrogel 1% are too expensive for many rosacea sufferers, even those with basic medical insurance.

Thanks to a tip from chenoarae; Oracea and Metrogel 1% are both available for free for residents of the US who don’t have insurance of any sort and are on a low income.

Some pharmaceutical companies offer a Patient Assistance Program (PAP) where they provide their …

15. Rosaliac UV Fortifying Anti-Redness Moisturizer with SPF 15

April 8th, 2010, by David Pascoe

La Roche-Posay are not particularly well known in the rosacea world but they do sponsor the National Rosacea Society and have a range …

16. Treating Dry Eye with Intense Pulsed Light

April 7th, 2010, by David Pascoe

KGMH Denver Channel 7 has a piece today, Drop-Free Dry Eye Treatment, highlighting the use of IPL for treating suffers of chronic Dry Eye.

17. Behind the statistics are Real People

April 2nd, 2010, by E.L. Hodge

A.D. 63.  Rome.  Public speaking is central to political and cultural life: an ordeal for most people; a nightmare for Roman rosaceans. The philosopher, Seneca, offers consolation to Lucilius, who is likely afflicted with ruddiness, flushing and blushing. ‘Certain people have ordinary blood,’ he says, ‘ and others just have an animated, lively sort of blood that comes to the face quickly.’

Rosacea News March 2010

Rosacea News March 2010

1. Rosacea is just a drop in the Internet Ocean

March 31st, 2010, by David Pascoe | in the news |

Those that have been around the rosacea online community for a while tend to be very focused on rosacea. If you ask Google how many people are searching for particular keywords you can see a bit more perspective on where rosacea fits in the global internet consciousness….

2. Biochemics Patents Vasoactives to Enhance Laser Treatments

March 30th, 2010, by E.L. Hodge | flushing, laser therapy, patents |

Today we welcome a new writer for Rosacea News – E.L. Hodge. Great to have you and we are all looking forward to hearing more of your thoughts !

How to best optimize laser and IPL treatments has long been debated. Should the rosacean deliberately engineer a flush prior to treatment? Should anti-inflammatories or anti-hypertensives be taken after treatment? Of course, many have long since reached …

3. RRDi Calling for Papers for Volume 2

March 29th, 2010, by David Pascoe | research foundation |

Following on from RRDi publishes first edition of their Rosacea Journal is a call for papers for the next Volume. Call for Papers, RRDi Journal Volume 2 We welcome articles on any aspect of rosacea for the second volume of the RRDi Journal. Health professionals and researchers are invited to submit research articles, clinical trial …

4. British film crew seeks NHS patient with rosacea

March 27th, 2010, by David Pascoe | in the news |

A production company is preparing to shoot a film on rosacea for the NHS Choices website and would like to include a case study. The ideal candidate would be someone whose rosacea is being treated by a dermatologist under the NHS, who is progressing well with those treatments, and can speak fluently about what is involved. They will also be interviewing a rosacea specialist/dermatologist, who …

5. Galderma’s President on the dermatology market

March 25th, 2010, by David Pascoe | galderma, in the news |

A few short quips from the President of Galderma, François Fournier, on his thoughts on the dermatology market. Just a couple of points below that were interesting. For one, Galderma invests more in R&D

6. Oracea should be tested against Generic Doxycycline

March 24th, 2010, by David Pascoe | galderma, oracea, tetracyclines |

This just published abstract is looking at recent advances in the use of the tetracycline family in treating rosacea. Of course a lot of the interest in subantimicrobial dose doxycyline has been motivated by the introduction of the Oracea to the market. A previous published study instigated by Collagenex (now owned by Galderma) showed that 100mg doxycycline was no better than oracea in …

7. April is Rosacea Awareness Month, spread the word

March 23rd, 2010, by David Pascoe | in the news, research foundation |

I haven’t ever got that excited about the annual awareness month for rosacea, as, well I’m quite aware of it.

It is obvious though, from looking around the population that plenty of people are not aware of the condition.

Why don’t you, as a reader of Rosacea News, do something …

8. rhinophyma (permanent rosacea nose) research updates

March 20th, 2010, by David Pascoe | rhinophyma |

A few updates for rhinophyma have been published recently, worth mentioning here as a quick update. Carbon dioxide laser treatment of rhinophyma: a review of 124 patients. (Br J Dermatol. 2009 Oct;161(4):814-8. Epub 2009 Jul 14.) Gives the conclusion that “The CO2 laser is an effective and durable treatment for rhinophyma. Treatment carries …

9. Clarifoam EF good for Rosacea, Acne and Seborrheic Dermatitis

March 19th, 2010, by David Pascoe | acne treatments, seborrheic dermatitis,topicals, user reviews |

This just published paper details a `new’ product that comprises a slight twist on an old formula. It seems that much of modern research and development involves tweaking existing treatments to see how their efficacy and product lifecycle can be extended.

This new product is known as CLARIFOAM EF Emollient Foam, …

10. Clinique Even Better Skin Tone Corrector, is it for you ?

March 17th, 2010, by David Pascoe | clinique, skin care |

“Here’s the chance to virtually undo the visible evidence of sun damage, dark patches, age spots, even acne scarring. Gently. For all ethnicities”. So says the promotional material for Clinique’s Even Better Tone Corrector and makeup. “Not even a leading prescription ingredient is faster in creating a more even skin tone”. Sounds too good to be true. Also sounds like it might be …

11. RRDi publishes first edition of their Rosacea Journal

March 16th, 2010, by David Pascoe | research, research foundation |

Brady Barrows has announced that the RRDi has published the Journal of the Rosacea Research & Development Institute: Volume 1 Number 1, 2010. The journal has been produced by volunteer rosacea sufferers and consists of `articles by …

12. Finacea Plus (get $2 off CeraVe and $10 off Finacea)

March 12th, 2010, by David Pascoe | finacea |

Many rosacea sufferers don’t get to see how the large pharmaceutical companies are marketing rosacea treatments to physicians. The program list from the recent AAD meeting in Florida gives an idea of where and how these companies think they can best promote their prescription products. Recently Rosacea News highlighted what is seen as Galderma’s quest to own the rosacea market. Here we …

13. Can you treat Acne with your iPhone ?

March 10th, 2010, by David Pascoe | LED Therapy, acne treatments |

Thanks to ClinuvelNews for highlighting the a $1.99 USD application available for your iPhone that is said to treat your acne. The application displays a red or blue screen which you then hold up to your face, supposedly allowing your skin to be treated while you make a phone call. Here are example screen shots of what the introductory and red and blue …

14. Galderma wants to own the Rosacea Market

March 8th, 2010, by David Pascoe | galderma, in the news |

Galderma is a large multinational pharmaceutical company. They don’t have much in the way of internet blogs and online chatter so it is hard to get a feel for what makes them tick. In recent years Galderma has become the heavyweight of dermatology, especially in rosacea treatments. The program list from the recent AAD meeting in Florida gives an idea of where Galderma …

15. Dermalogica Close Shave Oil, it really works !

March 5th, 2010, by David Pascoe | shaving, skin care, user reviews |

I have to admit that I hate shaving. It seems such a waste of time to me. Every morning I need to devote 10-15 minutes to scrape the dead wire-like hair off my face. Not only is it messy, but it hurts. I have tried an electric …

16. Microskin now available in the US

March 4th, 2010, by David Pascoe | makeup, topicals |

Recently that the Australian company Microskin has opened an office in New York. The Brisbane office opened in July 2005, with the NY office opening in January 2010. Microskin mention rosacea as one of the conditions that they treat. The product is slated as a simulated second skin. The product is applied using a Stipple (a special type of sponge) …

17. Assess your skin age and apparent likelihood to get rosacea

March 3rd, 2010, by David Pascoe | in the news |

A recent article from ABC7 featuring a skin analysis tool called VISIA Complexion Analysis System. The article suggests that the system uses multiple measures, including a porphyrin count to predict how likely a person is to get acne or …

18. NYP Hospital looking for trial participants, oral rosacea treatment

March 2nd, 2010, by David Pascoe | clinical trials |

Department of Dermatology, New York Presbyterian Hospital at Columbia University The Clinical Research Unit is seeking men and women, at least 18 years old, to participate in a research study of a new oral investigational treatment for Rosacea. The study requires 10 visits over 16 weeks. Participants may be eligible to receive: Free facial skin examinations …

Rosacea Skin Care

Finding what Rosacea Skin Care regime works for you is almost the most important step that any rosacea sufferer can take. It seems a bit too simple to be decisive, but time and time again we read about rosacea sufferers who get a heap better after they find the best moisturizer, sunscreen, cleanser even makeup that suits them.

Rosacea News Jan/Feb 2010

1. Rosacea features on ABC-TV’s Good Morning America Health

ABC-TV’s Good Morning America Health has featured rosacea in a 7 minute segment broadcast on January 21st.

On the table you can see Oracea, Metrogel and Cetaphil products, all from Galderma. One shot shows the new Cetaphil UVA/UVB Defence SPF 50 as well …

2. Prescription topicals go on first

When rosacea sufferers are first diagnosed it can be confusing to know how to include prescription topicals into their daily skincare regime. Rosacea patients want to know both that their expensive prescription medication has the best chance of working …

3. Apremilast from Celgene being trialled for rosacea

The first time you hear of a new drug, you probably ask – what is it ? Well are you ready for a marketing mouthful – “Apremilast is a novel, orally available small molecule compound that exhibits anti-inflammatory activities through the suppression of multiple pro-inflammatory mediators including, TNF-alpha, interleukins 6, 17 & 23, and interferon-gamma among others.” Apremilast (CC-10004) has been trialled for …

4. Q&A with Clinuvel on Afamelanotide and Melanotan

There is a lot of interest amongst rosacea sufferers surrounding the possibility of some kind of systemic treatment that will offer better UV protection. Especially for those with severe triggers from sun exposure, treatments like Afamelanotide look promising. The CEO and Director of Clinuvel, Dr Philippe Wolgen, was kind enough to answer some questions relating to their developments and any potential tie-in with …

5. Nielson disciplined over Nase’s misrepresentations

The Texas Medical Board has issued a press release with a list of their most recent discipline orders. One of its orders relates to Dr. David Nielson.

Dr. Nielson became known to rosacea sufferers via the way that his Rosacea Institute of Texas was heavily promoted by Geoffrey Nase. The results being promised and the treatment protocols proposed raised the suspicion of some rosacea …

6. Albert Kligman, Acne and Rosacea Pioneer dies at age 93

The name Albert Kligman has been associated with dermatology for a very long time. Perhaps best known for his work with the acne treatment Retin-A, Dr. Kligman is credited with more than 1,500 publications on acne, rosacea, eczema, contact dermatitis and skin aging. According to Albert M. Kligman, 93, dermatology researcher, Dr. Kligman cowrote 14 books, beginning with Textbook on Dermatology, published by …

7. Just how many people have Rosacea ?

The prevalence of rosacea is an often reported fact. Most media releases will start with a statement of the number of rosacea sufferers in the US.

The latest 2010 estimates from the NRS suggest that 16 million Americans suffer from rosacea, up from the last estimate of …

8. 7 Up and Coming Acne Treatments

A recent abstract has highlighted some new acne treatments that perhaps many haven’t heard of before.  As these treatments might not be on the radar for rosacea sufferers I thought it might be useful to highlight them here. Veteran rosacea sufferers will know that many acne treatments are too harsh for rosacea sufferers. Experience seems to show though, that some rosacea sufferers can tolerate …

9. Photodynamic Therapy is being used for cancer too

Photodynamic Therapy (a treatment usually consisting of a photosensitizing agent, light and tissue oxygen) is gaining popularity for its ability to treat more than just skin diseases. Internal organs and cancer sites are now being treated with PDT using endoscopes and fibre optic catheters. Even though some research papers about rosacea and PDT are available, as a rosacea treatment the usage of …

10. Suffering as bad as it gets; Erythropoietic Protoporphyria

A blog posting at Clinuvel interviews a family struggling with the severe disease Erythropoietic Protoporphyria. Parents Wendy and Ralph talk about the distress and anguish at seeing their young children suffer the pain of EPP. Also known as absolution light intolerance, Erythropoietic Protoporphyria (EPP) is caused by a build up of protoporphyrin in the skin. Exposure to the sun causes these molecules to …

11. Natural treatments may be deadly

Several Australian newspapers are running a story today about the risk that comes when people self-diagnose, self-treat and buy supplements off the shelf of a supermarket.

The whole idea of natural treatments is very appealing to many rosacea sufferers. There is certainly a group of rosacea sufferers who see prescription treatments as too artificial and too likely to cause harm. As it almost always the case …

12. Rosacea Psychology questions answered

Every so often, when we are able to solicit the help of experts, the Rosacea Support Group assembles questions that we need answered. Recently we put some questions on the psychology of rosacea to Professor Peter Drummond, Ph.D., from the School of Psychology at Murdoch University in Perth, Western Australia, and his colleague Daphne Su, D.Psych, Clinical Psychologist (Registrar) with the Department of Health …

13. Dr. Syed charged for posing as a doctor

Quite a few news sites today are covering the filing of charges of and arraignment of rosacea identity “Dr. Syed”.

Known to rosacea sufferers as Tanweer A. Syed MD. PhD, 66 year old Timothy Syed Andersson is facing 51 felony charges including practicing medicine without a license, grand …

14. Aesthera Isolaz now targets rosacea symptoms

A recent segment on ABC-TV’s Good Morning America Health featured rosacea.

One slant put on this television story was promoted by a followup press release that highlights the use of Aesthera’s Isolaz technology.  In the past Aesthera’s combination of `pneumatic energy’ and broad band light has been used to treat the pustules and inflammation of acne.

most popular subscribed posts at rosacea-support.org

Visitors to http://rosacea-support.org can leave comments on any of many hundreds of blog pages. When a comment is left, the visitor is able to subscribe to a post. This allows them to receive an email when the next visitor leaves a comment.

Looking at the top subscribed pages gives an idea of how popular some pages have become. Here is a list of the top subscribed pages.

• lindasy.com is closing down
• ZincO, Vita-Oil and Oatmeal Cleanser available again soon
• Oracea to replace Periostat, new rosacea treatment launched
• Australia
• just how do you kill demodex mites ?
• Finacea (azelaic acid 15%) as a Rosacea Treatment
• how to cure a red face (facial erythema or redness)
• Prosacea User Reviews
• demodex mites treatment
• Photos of Red Nose, Papules, Pustules, acne like rosacea
• metronidazole (metrogel, flagyl) popular rosacea treatment
• red face: when flushing isn’t rosacea
• treating steroid induced rosacea
• Frequently Asked Questions
• My Rosacea Treatments: rozex, doryx, cutanix, ZincO
• Clinique Redness Solutions: user reviews
• melanotan: could it cause skin cancer ?
• IPL is excellent for rosacea
• Teating Ocular Rosacea (from the AAO)
• pain, swelling and redness after pulse dye laser treatments
• aveeno ultra calming with feverfew: product reviews
• treating rosacea with herbs and other natural rosacea treatments
• Eucerin Redness Relief: product reviews
• sea buckthorn oil soap: user reviews
• SIBO eradication clears rosacea: are you serious ?

how do you find cheap rosacea treatments ?

So just how do you find cheap rosacea treatments ? Ask any rosacea sufferer and they will cringe when quizzed on the cost of treatments. Especially prescription treatments are scary, but even the stuff that the cosmetics counter will try to sell you will hurt your pocket.

In my quest to cut through the needless expenses here is my list of the cheapest ways to treat rosacea.

Rosacea News December 2009

Rosacea News December 2009

1. Feeling depressed about rosacea ? get some help here

Does coping with rosacea sometimes get you down ? Finding good advice on how to cope with the anxiety of rosacea can be hard to find. Well now you have an opportunity to ask some questions of experts. Psychology Question and Answer session Professor Peter Drummond, Ph.D., from the School of Psychology at Murdoch University …

2. Afamelanotide continues promising results

Clinuvel is announcing more positive results with its trial of the melanin boosting drug afamelanotide for the disease polymorphic light eruption (PLE). Even though this condition is rare and it is a stretch to say that treating rosacea with this drug is a given, it is still interesting to follow the development of this drug. Today’s press release relate to the continuing …

3. Standard Management Options: according to Subtype

This paper is Part 2 in the series of Standard Management Options for Rosacea. Part 1 was devoted to the Overview and Broad Spectrum of Care. Now, Part 2 will expand to discuss management options according to the …

4. Standard Management Options: Broad Care

Authored by a who’s who of Rosacea Experts, the National Rosacea Society has again brought about a publication that puts a stake in the ground for rosacea treatment and management. …

5. What do you want to see on rosacea.org ?

The National Rosacea Society wants your input to determine what information you would like to see on their web site. As the most popular rosacea web site on the internet, rosacea.org is often the first stop for newly diagnosed …

6. Glowelle Beauty Drinks – a rosacea supplement ?

Nestle, who along with L’Oreal are the parent company of Galderma, is promoting a beauty drink called glowelle. Their buzz word rich marketing includes references to antioxidants, phyto-nutrients, botanical fruit extracts and more. The ingredients are said to fight harmful …

7. Finacea Foam being trialled

We’ve seen it with metrogel; the pharmaceutical companies want to expand the market for their existing successful products by creating followup products. A Clinical Trial is underway to test Finacea Foam for the papules and pustules of rosacea. Finacea has proved to be a good option for the `acne like’ symptoms of rosacea. Safety and Efficacy of …

8. Book Review: Rosacea: Diagnosis and Management, Frank C. Powell

Professor Frank Powell has created something quite valuable for rosacea sufferers and their physicians, an authorative and approachable medical text. Author: Frank C. Powell Review Date: December 2009 Available at Amazon.com …

9. Efracea is the UK version of Oracea

Publications filed with the UK and EU health and approval authorities suggest that Galderma is marketing the 40mg modified release doxycycline (known as Oracea in the US) as Efracea in the United Kingdom. Other member countries …

Standard Rosacea Treatment Options

Lets do some quick revision. In 2002, the National Rosacea Society Expert Committee reported on a standard classification system that identified primary and secondary features of rosacea and described 4 common patterns of signs and symptoms designated as subtypes. In 2004, the committee published a standard grading system for assessing the relative severity of rosacea to enhance the utility of the classification system for researchers and clinicians.

The standard management options were developed by a consensus committee and review panel of 26 experts to assist in providing optimal patient care based on the standard classification and grading systems for rosacea that were developed to perform research; analyze results and compare data from different sources; and provide a common terminology and reference for the diagnosis, treatment, and assessment of results in clinical practice. We discuss standard management options for rosacea in 2 parts: (1) overview and broad spectrum of care, and (2) options according to subtype. The options are considered provisional and may be expanded and updated as appropriate. Managing the various potential signs and symptoms of rosacea calls for consideration of a broad spectrum of care, and a more precise selection of therapeutic options may become increasingly possible as the mechanism of action of therapies are more definitively established.

Now, see the rosacea experts thoughts on Standard Management Options 1: overview and broad spectrum of care and the Standard Management Options 2: according to subtype and while you are at it - Book Review: Rosacea Diagnosis and Management .

Rosacea News November 2009

Rosacea News November 2009

1. NY Derm likes Finacea instead of Retin-A

In an ELLE Magazine December 2009 interview, New York Dermatologist Macrene Alexiades-Armenakas, MD, PhD tells us that she has rosacea. A respected and published dermatologist, Dr. Alexiades-Armenakas says that she is one of the …

2. Promiseb even better than Desonide 0.05%

Promiseb Topical Cream has been found to be as effective as desonide cream 0.05% when treating facial dermatitis. This is an exciting finding, especially if the results can be replicated at large in the rosacea / seborrheic dermatitis community. …

3. What is this mysterious Nycomed 0444 Gel ?

The Clinical Trials register has listed a just completed trial for something cryptically called 0444 Gel. The Gel is targeted for the papules and pustules of rosacea. Apparently the study started in January 2008 and has just been completed. Study of 0444 Gel in the Treatment of Inflammatory Lesions of Rosacea Sponsor: Nycomed US Inc …

4. Accutane dose of 22mg a day works best: EADV

A summary from a the recent 18th Congress of the European Academy of Dermatology and Venereology has presented some findings relating to the most effect dosage of accutane to treat rosacea. Accutane (Isotretinoin) has been successfully prescribed in …

5. Vitamin K Oxide good for purpleness after PDL

A recently published paper is proposing the use of Vitamin K Oxide (Phytonadione Epoxide Hexane) as a treatment to accelerate the recovery from the redness and purple lesions following Pulsed Dye Laser. A previous study in 1994 also found that Vitamin K cream reduced the severity of post PDL purpura. Whilst the redness and indeed purpleness that Pulsed Dye Laser treatments can …

6. DER45-EV Gel from Sol-Gel files for IND

News today that Sol-Gel Technologies has filed for Investigational New Drug for a product they are calling DED45-EV. This topical gel is targeted as a treatment for rosacea.

There doesn’t seem to be other copies of this release, or related information so this could just be a pure PR exercise.

7. Treating Rosacea with Infrared Light: Patent

A newly filed patent contains a proposed rosacea treatment using small bands of infrared radiation between 790nm and 900nm with a power between 1 and 100 mW/cm^2. The unit proposed could be a LED device, used from twice a day to every 10 days. An energy density between 3 and 180 Joules/cm^2 is proposed.

Book Review: Rosacea: Diagnosis and Management, Frank C. Powell

Professor Frank Powell has created something quite valuable for rosacea sufferers and their physicians, an authorative and approachable medical text.

Author: Frank C. Powell
Review Date: December 2009
Available at Amazon.com

READ The full book review here:

Rosacea Diagnosis and Management.

Conclusion

This book gets off to an excellent start because the author is a genuine rosacea expert who is widely recognised. Professor Powell’s book is the sort of text that will see the understanding of rosacea symptoms, diagnosis and treatment increase world wide.

This book is by and far the best book on rosacea that you can get your hands on.

You can purchase the book at Amazon.com: Rosacea Diagnosis and Management.

See Also: other Rosacea Book Reviews

Rosacea News October 2009

Rosacea News October 2009

1. Oracea wins award for cute marketing

I can’t say that I know how much industry weight is carried by the publication Medical Marketing & Media, but they have awarded Galderma the Gold Award for `Best Individual Product Advertisement in Consumer Press’ for their …

2. Cetaphil adds UVA/UVB Defense SPF 50

Galderma announced in February a new SPF 50 Facial Sunscreen called Cetaphil UVA/UVB Defense SPF 50. Actually Galderma is not promoting this product as a sunscreen, but as a facial moisturizer. Said to be non-greasy and ..

3. Claim your Rosacea Community Blog Now !

Always wanted to have a blog or little corner of the internet you could call your own ? Well now you can. Every registered member of the Rosacea Support Community can have their very own blog area.

So please feel free to start your own Rosacea Community Blog.
Why would I want one of those ?
Your own blog will allow you post your thoughts, ideas, ..

4. IPL good for dry eyes too

WSOC-TV Charlotte, Carolina is syndicating a story about using IPL to successfully treat dry eye. Dr. Coad details how he is using IPL to treat this eye condition that is sometimes also found in ocular rosacea sufferers. Dr. Mannis in his interview for the RSRP had this to say about IPL and ocular rosacea. Q: Do you think ..

5. Topical Oxygen being trialled for sun damaged skin

A trial seeking participants interested in being treated with topically disolved oxygen (TDO) has been posted to clinicaltrials.gov. Aria Aesthetics is listed as supplying the `Aria Regimens’ in 0.5%, and 0.25%. As the trial is double blind and placebo controlled, a third group will receive no TDO during their treatments. Zoe Draelos MD is listed as a contact for the trial. Dr. Draelos ..

6. Clarisonic now available in the UK

The Daily Mail has published an article reviewing the Clarisonic in their Femail Beauty section. This article is no doubt motivated by the Clarisonic recently being launched in the UK (available exclusively via Space NK). The `oversized electric toothbrush’ is ..

7. Sansrosa starts strength tests, approaches final hurdle

In an encouraging sign that Sansrosa is slowly but surely progressing towards FDA approval, the clinicaltrials.gov register lists Galderma recruiting for a dose-finding trial for a product code named CD07805/47. The aim of this trial is show which strength is the most suitable for general use. Trial participants will be using one of 4 different strengths: 0.07%, 0.18%, %0.50 or effectively %0 contained ..

8. NRS research results explained

The NRS has just posted an easy-to-read summary of recent NRS funded research results. The update mentions the `Gallo Research’ and describes it ; “Dr. Richard Gallo at the University of California-San Diego found a consistently aberrant innate immune response in individuals with rosacea to environmental and emotional triggers.” Spin-off research related to type I interferon, plasmacytoid dendritic cells and enzyme involvement ..

9. Tetracyclines and Rosacea: what we already knew

Reading this just published abstract highlights for me just how slowly indeed research moves along. These recently proposed methods of action of tetracyclines seem to embody far from ground breaking research. We learnt in 2007 that tetracyclines have anti-inflammatory actions:  “Tetracyclines are known to exhibit multiple significant anti-inflammatory actions … the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation.

Rosacea News August/September 2009

Rosacea News August 2009

1. water soluble sunscreen anyone ?

An interesting looking patent application proposing a water based sunscreen for rosacea sufferers has surfaced at the USPTO. Many rosacea sufferers will know the trauma of finding a sunscreen that is gentle enough to not cause a bad reaction and effective enough to protect from the harm of the sun. For me the sun has always been my worst trigger. Certainly physical sunscreens …

2. so does acupuncture work, or not ?

For me acupuncture has always been part of some kind of ancient mythology. Humans are controlled by a brain that has complex neurological pathways to all corners of their bodies. Can inserting fine needles in to the so-called meridians along energy …

3. Epsom salts or Milk of Magnesia actually works ?

A few newspapers have picked up this Question & Answer article where rosacea sufferers are encouraged to try Epsom salts (magnesium sulfate) or Milk of Magnesia on their skin.

One can imagine that a bath with Epsom salts would be relaxing, but …

4. Sebclair launches as Promiseb Cream

I was alerted to the launch of a product called Promiseb by a comment left on the Sebclair for Seborrheic Dermatitis post. Since then the news web sites are also covering the press release. Promiseb (probably pronounced Promi-seb) is launching in the U.S. via Promius Pharma, after being licensed from Sinclair Pharma in 2007….

Rosacea News September 2009

1. Oracea worth $104m a year, good news for Sansrosa

According to a press release via Reuters, sales of Oracea were approximately $104 million for the twelve-month period ending July 2009. This figure is up almost 200% from the previously reported sales of $52.5 million in …

2. Impax Laboratories joins the generic Oracea battle

September 21st, 2009, by Digital Davo | oracea, patents | Edit

In a further confirmation that the low dose doxycycline market is a becoming a fighting ground, a recent press release states that Impax Laboratories has filed “Abbreviated New Drug Application ("ANDA") containing a paragraph IV certification for a generic version of ORACEA with the U.S. Food & Drug Administration ("FDA").” This is a challenge to the patents held by Galderma, relating …

3. PSF reduces the pain of Pulsed Dye Laser

This just published abstract from Lasers in Medical Science, shows that the extreme pain associated with pulsed dye laser, when used to treat port wine stains, can be relieved by using Pneumatic Skin Flattening (PSF). Pneumatic Skin Flattening uses a vacuum to compress the skin underneath the area being treated. Blood is eliminated from the treatment area. The technique is said …

4. FDA gets tough with Aczone

The FDA has issued a warning letter to Allergan, the makers of Aczone for overstating the efficacy of Aczone and also for understating the possible side effects. In a sign that the FDA is watching carefully the claims that vendors use when advertising their products, the warning letter calls out a journal advertisement for Aczone as violating the Federal Food, Drug, and Cosmetic Act. …

Rosacea News August 2009

Rosacea News August 2009

1. water soluble sunscreen anyone ?

An interesting looking patent application proposing a water based sunscreen for rosacea sufferers has surfaced at the USPTO. Many rosacea sufferers will know the trauma of finding a sunscreen that is gentle enough to not cause a bad reaction and effective enough to protect from the harm of the sun. For me the sun has always been my worst trigger. Certainly physical sunscreens …

2. so does acupuncture work, or not ?

For me acupuncture has always been part of some kind of ancient mythology. Humans are controlled by a brain that has complex neurological pathways to all corners of their bodies. Can inserting fine needles in to the so-called meridians along energy …

3. Epsom salts or Milk of Magnesia actually works ?

A few newspapers have picked up this Question & Answer article where rosacea sufferers are encouraged to try Epsom salts (magnesium sulfate) or Milk of Magnesia on their skin.

One can imagine that a bath with Epsom salts would be relaxing, but …

4. Sebclair launches as Promiseb Cream

I was alerted to the launch of a product called Promiseb by a comment left on the Sebclair for Seborrheic Dermatitis post. Since then the news web sites are also covering the press release.

Rosacea News July 2009

Rosacea News July 2009

1. Doxium being trialled as Pulsed Dye Laser adjunct

A new trial is recruiting participants to evaluate the use of calcium dobelisate as a combination therapy, along with Pulse Dye Laser to treat the erythema, flushing and telangectasia associated with erythematotelangietatic rosacea. We know from rosacea and doxium that “Calcium dobesilate is a vasoactive drug with presumed effects on endothelial integrity, capillary permeability and blood viscosity.” Clinical Trial …

2. Calling all Rosacea Researchers: get your grants now !

The National Rosacea Society is calling for grant applications for their 2010 allocation. Good to see that they want an emphasis on research into the cause rosacea. From New Grants Available Monday, July 27, 2009 New grants are available from the National Rosacea Society (NRS) to support research on potential causes and other …

3. Abstracts: Elidel, Bacteria & Ocular prevalence

The following abstracts don’t deserve a Rosacea News item on their own, but are interesting enough to give a mention here in this Abstract Roundup. Elidel no better than Metrogel for lumps and bumps of rosacea. A comparison of metronidazole 1% cream and pimecrolimus 1% cream in the treatment of patients with papulopustular rosacea: a randomized open-label clinical trial. Clin Exp Dermatol. 2009 …

4. Sol-Gel Trialling Benzoyl Peroxide (DER 45 EV) for Rosacea ?

An intriguing Clinical Trial has been listed on the ClinicalTrials.gov web site. The product know only as DER 45 EV Gel (in strengths of 1% and 5%) has been listed in a dose-range trial for the papules and pustules of rosacea. Clinical Trial NCT00940992, A Dose-Range of DER 45-EV in Treatment of Rosacea (SGT-EBPO1-09) …

5. we’ve all been exposed to demodex bacteria proteins ?

An article published today in the Irish Times takes one more step in the direction of showing an association between demodex mites and rosacea. Readers of Rosacea News will know that a lot of research has tried to find a causative link between the presence of demodex mites and rosacea symptoms. Some progress towards a link between the two was …

6. acupuncture, yoga, hat and moisturiser says Daily Mail

We are seeing more and more newspaper health and beauty articles that relate to rosacea. Today the UK’s MailOnline has an intriguingly titled article – How waggling my feet has helped my red face. To save you …

7. accutane and drinking alcohol – no problem, apparently

This just published abstract is suggesting that it appears to be safe to consume alcohol while taking accutane. Whilst the Accutane Prescribing Information does not prohibit the consumption of alcohol, it does suggest that alcohol …

8. CeraVe Hydrating Cleanser and CeraVe Moisturizing Lotion User Reviews

Recently the manufacturers of Finacea, Intendis, and Coria Laboratories, have begun promoting a new combination package it is calling Finacea plus. This package encourages rosacea sufferers to combine a tube of Finacea with CeraVe Hydrating …

9. Restasis (cyclosporine) as ocular rosacea treatment

It is good to see more published research backing topical cyclosporine (Restasis, Allergan) as a treatment for ocular rosacea. Restasis (cyclosporine ophthalmic emulsion 0.05%) has been shown to increase tear production and improve the quality of naturally produced tears and is …

Rosadyn Vasculokinetic and Skin Health Support

The Rosadyn site is full of scientific terminology.

Addresses all symptoms of Rosacea: Facial Redness and flushing skin inflammation and sensitivity inflammatory bumps and breakouts.

Advanced non-prescription oral nutraceutical for vascular, ocular and skin support

Targets the root precursors of facial redness, inflammation and flushing.

Developed by Dr. Geoffrey Nase PhD., Rosacea Specialist and Researcher.

Further claims about Rosadyn: advanced pharmaceutical-grade nutraceutical, vasculokinetic, Absorption Enhancement Blend, Hypothalamus Support, Hypothalamic overdrive.

Rosacea News June 2009

Rosacea News June 2009

1. doryx + applesauce, for those who can’t swallow tablets

If you have trouble swallowing tablets, here is an official FDA sanctioned tip. Open the tablet and sprinkle the delayed release pellets on to a spoonful of applesauce. This is a good option for anyone who finds swallowing the …

2. NYTimes says no natural remedies for rosacea

The New York Times has an article today keenly titled Natural Remedies for Rosacea?. The question is one that many rosacea sufferer seek answered – are there any effective treatments for rosacea that don’t include the use of antibiotics or prescription potions and lotions ? The answer comes from one of the premier rosacea experts – Dr. Frank C. Powell. Here is an extract …

3. Favourite Over The Counter treatments

Do you have a favourite over the counter treatment for your rosacea ? Depending on your health insurance and access to doctors and pharmacies, prescription treatments are out of the reach of many rosacea sufferers. So what can you try as a rosacea treatment that is easy to source, cheap and …

4. Vita-Oil Release Next Week. Tinted ZincO in July

Here is an announcement from RosaceaCare: “Earlier this year, we announced that four important and popular rosacea products that had been unavailable for many months would thereafter, by special arrangement with the originator, be manufactured and distributed by the Rosacea Care Company. We are pleased to tell you that the first of these, the much-loved Vita-Oil, will be released and ready to ship this …

5. Is Oracea different to 50mg doxycycline ?

I came across the following graph in a recent presentation at the recent AAD meeting and figured it was interesting enough to highlight it here. The following graph, sourced from Collagenex (who sell Oracea), shows the blood plasma concentration of doxycycline after taking Oracea compared to 50mg once a day of generic doxycycline. The horizontal axis stretches out to 24 hours post dosage. …

6. Doxium (calcium dobesilate) trialists wanted

Thanks to a comment from Sophie on the post rosacea and doxium (calcium dobesilate) we know that Dr. Cuevas who is responsible for several papers on Dobesilate, is accepting people to try it as a treatment for rosacea. Thanks for the info Sophie.

7. Green Tea helps after IPL

This just published paper is suggesting that the topical application of polyphenol antioxidants (aka green tea) post IPL treatment resulted in more hydrated skin and reduced oxidative degradation of skin lipids. The authors suggest that this will enhance the effects of the IPL therapy.