Rosacea News March 2010

Rosacea News March 2010

1. Rosacea is just a drop in the Internet Ocean

March 31st, 2010, by David Pascoe | in the news |

Those that have been around the rosacea online community for a while tend to be very focused on rosacea. If you ask Google how many people are searching for particular keywords you can see a bit more perspective on where rosacea fits in the global internet consciousness….

2. Biochemics Patents Vasoactives to Enhance Laser Treatments

March 30th, 2010, by E.L. Hodge | flushing, laser therapy, patents |

Today we welcome a new writer for Rosacea News – E.L. Hodge. Great to have you and we are all looking forward to hearing more of your thoughts !

How to best optimize laser and IPL treatments has long been debated. Should the rosacean deliberately engineer a flush prior to treatment? Should anti-inflammatories or anti-hypertensives be taken after treatment? Of course, many have long since reached …

3. RRDi Calling for Papers for Volume 2

March 29th, 2010, by David Pascoe | research foundation |

Following on from RRDi publishes first edition of their Rosacea Journal is a call for papers for the next Volume. Call for Papers, RRDi Journal Volume 2 We welcome articles on any aspect of rosacea for the second volume of the RRDi Journal. Health professionals and researchers are invited to submit research articles, clinical trial …

4. British film crew seeks NHS patient with rosacea

March 27th, 2010, by David Pascoe | in the news |

A production company is preparing to shoot a film on rosacea for the NHS Choices website and would like to include a case study. The ideal candidate would be someone whose rosacea is being treated by a dermatologist under the NHS, who is progressing well with those treatments, and can speak fluently about what is involved. They will also be interviewing a rosacea specialist/dermatologist, who …

5. Galderma’s President on the dermatology market

March 25th, 2010, by David Pascoe | galderma, in the news |

A few short quips from the President of Galderma, François Fournier, on his thoughts on the dermatology market. Just a couple of points below that were interesting. For one, Galderma invests more in R&D

6. Oracea should be tested against Generic Doxycycline

March 24th, 2010, by David Pascoe | galderma, oracea, tetracyclines |

This just published abstract is looking at recent advances in the use of the tetracycline family in treating rosacea. Of course a lot of the interest in subantimicrobial dose doxycyline has been motivated by the introduction of the Oracea to the market. A previous published study instigated by Collagenex (now owned by Galderma) showed that 100mg doxycycline was no better than oracea in …

7. April is Rosacea Awareness Month, spread the word

March 23rd, 2010, by David Pascoe | in the news, research foundation |

I haven’t ever got that excited about the annual awareness month for rosacea, as, well I’m quite aware of it.

It is obvious though, from looking around the population that plenty of people are not aware of the condition.

Why don’t you, as a reader of Rosacea News, do something …

8. rhinophyma (permanent rosacea nose) research updates

March 20th, 2010, by David Pascoe | rhinophyma |

A few updates for rhinophyma have been published recently, worth mentioning here as a quick update. Carbon dioxide laser treatment of rhinophyma: a review of 124 patients. (Br J Dermatol. 2009 Oct;161(4):814-8. Epub 2009 Jul 14.) Gives the conclusion that “The CO2 laser is an effective and durable treatment for rhinophyma. Treatment carries …

9. Clarifoam EF good for Rosacea, Acne and Seborrheic Dermatitis

March 19th, 2010, by David Pascoe | acne treatments, seborrheic dermatitis,topicals, user reviews |

This just published paper details a `new’ product that comprises a slight twist on an old formula. It seems that much of modern research and development involves tweaking existing treatments to see how their efficacy and product lifecycle can be extended.

This new product is known as CLARIFOAM EF Emollient Foam, …

10. Clinique Even Better Skin Tone Corrector, is it for you ?

March 17th, 2010, by David Pascoe | clinique, skin care |

“Here’s the chance to virtually undo the visible evidence of sun damage, dark patches, age spots, even acne scarring. Gently. For all ethnicities”. So says the promotional material for Clinique’s Even Better Tone Corrector and makeup. “Not even a leading prescription ingredient is faster in creating a more even skin tone”. Sounds too good to be true. Also sounds like it might be …

11. RRDi publishes first edition of their Rosacea Journal

March 16th, 2010, by David Pascoe | research, research foundation |

Brady Barrows has announced that the RRDi has published the Journal of the Rosacea Research & Development Institute: Volume 1 Number 1, 2010. The journal has been produced by volunteer rosacea sufferers and consists of `articles by …

12. Finacea Plus (get $2 off CeraVe and $10 off Finacea)

March 12th, 2010, by David Pascoe | finacea |

Many rosacea sufferers don’t get to see how the large pharmaceutical companies are marketing rosacea treatments to physicians. The program list from the recent AAD meeting in Florida gives an idea of where and how these companies think they can best promote their prescription products. Recently Rosacea News highlighted what is seen as Galderma’s quest to own the rosacea market. Here we …

13. Can you treat Acne with your iPhone ?

March 10th, 2010, by David Pascoe | LED Therapy, acne treatments |

Thanks to ClinuvelNews for highlighting the a $1.99 USD application available for your iPhone that is said to treat your acne. The application displays a red or blue screen which you then hold up to your face, supposedly allowing your skin to be treated while you make a phone call. Here are example screen shots of what the introductory and red and blue …

14. Galderma wants to own the Rosacea Market

March 8th, 2010, by David Pascoe | galderma, in the news |

Galderma is a large multinational pharmaceutical company. They don’t have much in the way of internet blogs and online chatter so it is hard to get a feel for what makes them tick. In recent years Galderma has become the heavyweight of dermatology, especially in rosacea treatments. The program list from the recent AAD meeting in Florida gives an idea of where Galderma …

15. Dermalogica Close Shave Oil, it really works !

March 5th, 2010, by David Pascoe | shaving, skin care, user reviews |

I have to admit that I hate shaving. It seems such a waste of time to me. Every morning I need to devote 10-15 minutes to scrape the dead wire-like hair off my face. Not only is it messy, but it hurts. I have tried an electric …

16. Microskin now available in the US

March 4th, 2010, by David Pascoe | makeup, topicals |

Recently that the Australian company Microskin has opened an office in New York. The Brisbane office opened in July 2005, with the NY office opening in January 2010. Microskin mention rosacea as one of the conditions that they treat. The product is slated as a simulated second skin. The product is applied using a Stipple (a special type of sponge) …

17. Assess your skin age and apparent likelihood to get rosacea

March 3rd, 2010, by David Pascoe | in the news |

A recent article from ABC7 featuring a skin analysis tool called VISIA Complexion Analysis System. The article suggests that the system uses multiple measures, including a porphyrin count to predict how likely a person is to get acne or …

18. NYP Hospital looking for trial participants, oral rosacea treatment

March 2nd, 2010, by David Pascoe | clinical trials |

Department of Dermatology, New York Presbyterian Hospital at Columbia University The Clinical Research Unit is seeking men and women, at least 18 years old, to participate in a research study of a new oral investigational treatment for Rosacea. The study requires 10 visits over 16 weeks. Participants may be eligible to receive: Free facial skin examinations …

Rosacea Skin Care

Finding what Rosacea Skin Care regime works for you is almost the most important step that any rosacea sufferer can take. It seems a bit too simple to be decisive, but time and time again we read about rosacea sufferers who get a heap better after they find the best moisturizer, sunscreen, cleanser even makeup that suits them.

Rosacea News Jan/Feb 2010

1. Rosacea features on ABC-TV’s Good Morning America Health

ABC-TV’s Good Morning America Health has featured rosacea in a 7 minute segment broadcast on January 21st.

On the table you can see Oracea, Metrogel and Cetaphil products, all from Galderma. One shot shows the new Cetaphil UVA/UVB Defence SPF 50 as well …

2. Prescription topicals go on first

When rosacea sufferers are first diagnosed it can be confusing to know how to include prescription topicals into their daily skincare regime. Rosacea patients want to know both that their expensive prescription medication has the best chance of working …

3. Apremilast from Celgene being trialled for rosacea

The first time you hear of a new drug, you probably ask – what is it ? Well are you ready for a marketing mouthful – “Apremilast is a novel, orally available small molecule compound that exhibits anti-inflammatory activities through the suppression of multiple pro-inflammatory mediators including, TNF-alpha, interleukins 6, 17 & 23, and interferon-gamma among others.” Apremilast (CC-10004) has been trialled for …

4. Q&A with Clinuvel on Afamelanotide and Melanotan

There is a lot of interest amongst rosacea sufferers surrounding the possibility of some kind of systemic treatment that will offer better UV protection. Especially for those with severe triggers from sun exposure, treatments like Afamelanotide look promising. The CEO and Director of Clinuvel, Dr Philippe Wolgen, was kind enough to answer some questions relating to their developments and any potential tie-in with …

5. Nielson disciplined over Nase’s misrepresentations

The Texas Medical Board has issued a press release with a list of their most recent discipline orders. One of its orders relates to Dr. David Nielson.

Dr. Nielson became known to rosacea sufferers via the way that his Rosacea Institute of Texas was heavily promoted by Geoffrey Nase. The results being promised and the treatment protocols proposed raised the suspicion of some rosacea …

6. Albert Kligman, Acne and Rosacea Pioneer dies at age 93

The name Albert Kligman has been associated with dermatology for a very long time. Perhaps best known for his work with the acne treatment Retin-A, Dr. Kligman is credited with more than 1,500 publications on acne, rosacea, eczema, contact dermatitis and skin aging. According to Albert M. Kligman, 93, dermatology researcher, Dr. Kligman cowrote 14 books, beginning with Textbook on Dermatology, published by …

7. Just how many people have Rosacea ?

The prevalence of rosacea is an often reported fact. Most media releases will start with a statement of the number of rosacea sufferers in the US.

The latest 2010 estimates from the NRS suggest that 16 million Americans suffer from rosacea, up from the last estimate of …

8. 7 Up and Coming Acne Treatments

A recent abstract has highlighted some new acne treatments that perhaps many haven’t heard of before.  As these treatments might not be on the radar for rosacea sufferers I thought it might be useful to highlight them here. Veteran rosacea sufferers will know that many acne treatments are too harsh for rosacea sufferers. Experience seems to show though, that some rosacea sufferers can tolerate …

9. Photodynamic Therapy is being used for cancer too

Photodynamic Therapy (a treatment usually consisting of a photosensitizing agent, light and tissue oxygen) is gaining popularity for its ability to treat more than just skin diseases. Internal organs and cancer sites are now being treated with PDT using endoscopes and fibre optic catheters. Even though some research papers about rosacea and PDT are available, as a rosacea treatment the usage of …

10. Suffering as bad as it gets; Erythropoietic Protoporphyria

A blog posting at Clinuvel interviews a family struggling with the severe disease Erythropoietic Protoporphyria. Parents Wendy and Ralph talk about the distress and anguish at seeing their young children suffer the pain of EPP. Also known as absolution light intolerance, Erythropoietic Protoporphyria (EPP) is caused by a build up of protoporphyrin in the skin. Exposure to the sun causes these molecules to …

11. Natural treatments may be deadly

Several Australian newspapers are running a story today about the risk that comes when people self-diagnose, self-treat and buy supplements off the shelf of a supermarket.

The whole idea of natural treatments is very appealing to many rosacea sufferers. There is certainly a group of rosacea sufferers who see prescription treatments as too artificial and too likely to cause harm. As it almost always the case …

12. Rosacea Psychology questions answered

Every so often, when we are able to solicit the help of experts, the Rosacea Support Group assembles questions that we need answered. Recently we put some questions on the psychology of rosacea to Professor Peter Drummond, Ph.D., from the School of Psychology at Murdoch University in Perth, Western Australia, and his colleague Daphne Su, D.Psych, Clinical Psychologist (Registrar) with the Department of Health …

13. Dr. Syed charged for posing as a doctor

Quite a few news sites today are covering the filing of charges of and arraignment of rosacea identity “Dr. Syed”.

Known to rosacea sufferers as Tanweer A. Syed MD. PhD, 66 year old Timothy Syed Andersson is facing 51 felony charges including practicing medicine without a license, grand …

14. Aesthera Isolaz now targets rosacea symptoms

A recent segment on ABC-TV’s Good Morning America Health featured rosacea.

One slant put on this television story was promoted by a followup press release that highlights the use of Aesthera’s Isolaz technology.  In the past Aesthera’s combination of `pneumatic energy’ and broad band light has been used to treat the pustules and inflammation of acne.

most popular subscribed posts at rosacea-support.org

Visitors to http://rosacea-support.org can leave comments on any of many hundreds of blog pages. When a comment is left, the visitor is able to subscribe to a post. This allows them to receive an email when the next visitor leaves a comment.

Looking at the top subscribed pages gives an idea of how popular some pages have become. Here is a list of the top subscribed pages.

• lindasy.com is closing down
• ZincO, Vita-Oil and Oatmeal Cleanser available again soon
• Oracea to replace Periostat, new rosacea treatment launched
• Australia
• just how do you kill demodex mites ?
• Finacea (azelaic acid 15%) as a Rosacea Treatment
• how to cure a red face (facial erythema or redness)
• Prosacea User Reviews
• demodex mites treatment
• Photos of Red Nose, Papules, Pustules, acne like rosacea
• metronidazole (metrogel, flagyl) popular rosacea treatment
• red face: when flushing isn’t rosacea
• treating steroid induced rosacea
• Frequently Asked Questions
• My Rosacea Treatments: rozex, doryx, cutanix, ZincO
• Clinique Redness Solutions: user reviews
• melanotan: could it cause skin cancer ?
• IPL is excellent for rosacea
• Teating Ocular Rosacea (from the AAO)
• pain, swelling and redness after pulse dye laser treatments
• aveeno ultra calming with feverfew: product reviews
• treating rosacea with herbs and other natural rosacea treatments
• Eucerin Redness Relief: product reviews
• sea buckthorn oil soap: user reviews
• SIBO eradication clears rosacea: are you serious ?

how do you find cheap rosacea treatments ?

So just how do you find cheap rosacea treatments ? Ask any rosacea sufferer and they will cringe when quizzed on the cost of treatments. Especially prescription treatments are scary, but even the stuff that the cosmetics counter will try to sell you will hurt your pocket.

In my quest to cut through the needless expenses here is my list of the cheapest ways to treat rosacea.

Rosacea News December 2009

Rosacea News December 2009

1. Feeling depressed about rosacea ? get some help here

Does coping with rosacea sometimes get you down ? Finding good advice on how to cope with the anxiety of rosacea can be hard to find. Well now you have an opportunity to ask some questions of experts. Psychology Question and Answer session Professor Peter Drummond, Ph.D., from the School of Psychology at Murdoch University …

2. Afamelanotide continues promising results

Clinuvel is announcing more positive results with its trial of the melanin boosting drug afamelanotide for the disease polymorphic light eruption (PLE). Even though this condition is rare and it is a stretch to say that treating rosacea with this drug is a given, it is still interesting to follow the development of this drug. Today’s press release relate to the continuing …

3. Standard Management Options: according to Subtype

This paper is Part 2 in the series of Standard Management Options for Rosacea. Part 1 was devoted to the Overview and Broad Spectrum of Care. Now, Part 2 will expand to discuss management options according to the …

4. Standard Management Options: Broad Care

Authored by a who’s who of Rosacea Experts, the National Rosacea Society has again brought about a publication that puts a stake in the ground for rosacea treatment and management. …

5. What do you want to see on rosacea.org ?

The National Rosacea Society wants your input to determine what information you would like to see on their web site. As the most popular rosacea web site on the internet, rosacea.org is often the first stop for newly diagnosed …

6. Glowelle Beauty Drinks – a rosacea supplement ?

Nestle, who along with L’Oreal are the parent company of Galderma, is promoting a beauty drink called glowelle. Their buzz word rich marketing includes references to antioxidants, phyto-nutrients, botanical fruit extracts and more. The ingredients are said to fight harmful …

7. Finacea Foam being trialled

We’ve seen it with metrogel; the pharmaceutical companies want to expand the market for their existing successful products by creating followup products. A Clinical Trial is underway to test Finacea Foam for the papules and pustules of rosacea. Finacea has proved to be a good option for the `acne like’ symptoms of rosacea. Safety and Efficacy of …

8. Book Review: Rosacea: Diagnosis and Management, Frank C. Powell

Professor Frank Powell has created something quite valuable for rosacea sufferers and their physicians, an authorative and approachable medical text. Author: Frank C. Powell Review Date: December 2009 Available at Amazon.com …

9. Efracea is the UK version of Oracea

Publications filed with the UK and EU health and approval authorities suggest that Galderma is marketing the 40mg modified release doxycycline (known as Oracea in the US) as Efracea in the United Kingdom. Other member countries …

Standard Rosacea Treatment Options

Lets do some quick revision. In 2002, the National Rosacea Society Expert Committee reported on a standard classification system that identified primary and secondary features of rosacea and described 4 common patterns of signs and symptoms designated as subtypes. In 2004, the committee published a standard grading system for assessing the relative severity of rosacea to enhance the utility of the classification system for researchers and clinicians.

The standard management options were developed by a consensus committee and review panel of 26 experts to assist in providing optimal patient care based on the standard classification and grading systems for rosacea that were developed to perform research; analyze results and compare data from different sources; and provide a common terminology and reference for the diagnosis, treatment, and assessment of results in clinical practice. We discuss standard management options for rosacea in 2 parts: (1) overview and broad spectrum of care, and (2) options according to subtype. The options are considered provisional and may be expanded and updated as appropriate. Managing the various potential signs and symptoms of rosacea calls for consideration of a broad spectrum of care, and a more precise selection of therapeutic options may become increasingly possible as the mechanism of action of therapies are more definitively established.

Now, see the rosacea experts thoughts on Standard Management Options 1: overview and broad spectrum of care and the Standard Management Options 2: according to subtype and while you are at it - Book Review: Rosacea Diagnosis and Management .

Rosacea News November 2009

Rosacea News November 2009

1. NY Derm likes Finacea instead of Retin-A

In an ELLE Magazine December 2009 interview, New York Dermatologist Macrene Alexiades-Armenakas, MD, PhD tells us that she has rosacea. A respected and published dermatologist, Dr. Alexiades-Armenakas says that she is one of the …

2. Promiseb even better than Desonide 0.05%

Promiseb Topical Cream has been found to be as effective as desonide cream 0.05% when treating facial dermatitis. This is an exciting finding, especially if the results can be replicated at large in the rosacea / seborrheic dermatitis community. …

3. What is this mysterious Nycomed 0444 Gel ?

The Clinical Trials register has listed a just completed trial for something cryptically called 0444 Gel. The Gel is targeted for the papules and pustules of rosacea. Apparently the study started in January 2008 and has just been completed. Study of 0444 Gel in the Treatment of Inflammatory Lesions of Rosacea Sponsor: Nycomed US Inc …

4. Accutane dose of 22mg a day works best: EADV

A summary from a the recent 18th Congress of the European Academy of Dermatology and Venereology has presented some findings relating to the most effect dosage of accutane to treat rosacea. Accutane (Isotretinoin) has been successfully prescribed in …

5. Vitamin K Oxide good for purpleness after PDL

A recently published paper is proposing the use of Vitamin K Oxide (Phytonadione Epoxide Hexane) as a treatment to accelerate the recovery from the redness and purple lesions following Pulsed Dye Laser. A previous study in 1994 also found that Vitamin K cream reduced the severity of post PDL purpura. Whilst the redness and indeed purpleness that Pulsed Dye Laser treatments can …

6. DER45-EV Gel from Sol-Gel files for IND

News today that Sol-Gel Technologies has filed for Investigational New Drug for a product they are calling DED45-EV. This topical gel is targeted as a treatment for rosacea.

There doesn’t seem to be other copies of this release, or related information so this could just be a pure PR exercise.

7. Treating Rosacea with Infrared Light: Patent

A newly filed patent contains a proposed rosacea treatment using small bands of infrared radiation between 790nm and 900nm with a power between 1 and 100 mW/cm^2. The unit proposed could be a LED device, used from twice a day to every 10 days. An energy density between 3 and 180 Joules/cm^2 is proposed.

Book Review: Rosacea: Diagnosis and Management, Frank C. Powell

Professor Frank Powell has created something quite valuable for rosacea sufferers and their physicians, an authorative and approachable medical text.

Author: Frank C. Powell
Review Date: December 2009
Available at Amazon.com

READ The full book review here:

Rosacea Diagnosis and Management.

Conclusion

This book gets off to an excellent start because the author is a genuine rosacea expert who is widely recognised. Professor Powell’s book is the sort of text that will see the understanding of rosacea symptoms, diagnosis and treatment increase world wide.

This book is by and far the best book on rosacea that you can get your hands on.

You can purchase the book at Amazon.com: Rosacea Diagnosis and Management.

See Also: other Rosacea Book Reviews

Rosacea News October 2009

Rosacea News October 2009

1. Oracea wins award for cute marketing

I can’t say that I know how much industry weight is carried by the publication Medical Marketing & Media, but they have awarded Galderma the Gold Award for `Best Individual Product Advertisement in Consumer Press’ for their …

2. Cetaphil adds UVA/UVB Defense SPF 50

Galderma announced in February a new SPF 50 Facial Sunscreen called Cetaphil UVA/UVB Defense SPF 50. Actually Galderma is not promoting this product as a sunscreen, but as a facial moisturizer. Said to be non-greasy and ..

3. Claim your Rosacea Community Blog Now !

Always wanted to have a blog or little corner of the internet you could call your own ? Well now you can. Every registered member of the Rosacea Support Community can have their very own blog area.

So please feel free to start your own Rosacea Community Blog.
Why would I want one of those ?
Your own blog will allow you post your thoughts, ideas, ..

4. IPL good for dry eyes too

WSOC-TV Charlotte, Carolina is syndicating a story about using IPL to successfully treat dry eye. Dr. Coad details how he is using IPL to treat this eye condition that is sometimes also found in ocular rosacea sufferers. Dr. Mannis in his interview for the RSRP had this to say about IPL and ocular rosacea. Q: Do you think ..

5. Topical Oxygen being trialled for sun damaged skin

A trial seeking participants interested in being treated with topically disolved oxygen (TDO) has been posted to clinicaltrials.gov. Aria Aesthetics is listed as supplying the `Aria Regimens’ in 0.5%, and 0.25%. As the trial is double blind and placebo controlled, a third group will receive no TDO during their treatments. Zoe Draelos MD is listed as a contact for the trial. Dr. Draelos ..

6. Clarisonic now available in the UK

The Daily Mail has published an article reviewing the Clarisonic in their Femail Beauty section. This article is no doubt motivated by the Clarisonic recently being launched in the UK (available exclusively via Space NK). The `oversized electric toothbrush’ is ..

7. Sansrosa starts strength tests, approaches final hurdle

In an encouraging sign that Sansrosa is slowly but surely progressing towards FDA approval, the clinicaltrials.gov register lists Galderma recruiting for a dose-finding trial for a product code named CD07805/47. The aim of this trial is show which strength is the most suitable for general use. Trial participants will be using one of 4 different strengths: 0.07%, 0.18%, %0.50 or effectively %0 contained ..

8. NRS research results explained

The NRS has just posted an easy-to-read summary of recent NRS funded research results. The update mentions the `Gallo Research’ and describes it ; “Dr. Richard Gallo at the University of California-San Diego found a consistently aberrant innate immune response in individuals with rosacea to environmental and emotional triggers.” Spin-off research related to type I interferon, plasmacytoid dendritic cells and enzyme involvement ..

9. Tetracyclines and Rosacea: what we already knew

Reading this just published abstract highlights for me just how slowly indeed research moves along. These recently proposed methods of action of tetracyclines seem to embody far from ground breaking research. We learnt in 2007 that tetracyclines have anti-inflammatory actions:  “Tetracyclines are known to exhibit multiple significant anti-inflammatory actions … the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation.

Rosacea News August/September 2009

Rosacea News August 2009

1. water soluble sunscreen anyone ?

An interesting looking patent application proposing a water based sunscreen for rosacea sufferers has surfaced at the USPTO. Many rosacea sufferers will know the trauma of finding a sunscreen that is gentle enough to not cause a bad reaction and effective enough to protect from the harm of the sun. For me the sun has always been my worst trigger. Certainly physical sunscreens …

2. so does acupuncture work, or not ?

For me acupuncture has always been part of some kind of ancient mythology. Humans are controlled by a brain that has complex neurological pathways to all corners of their bodies. Can inserting fine needles in to the so-called meridians along energy …

3. Epsom salts or Milk of Magnesia actually works ?

A few newspapers have picked up this Question & Answer article where rosacea sufferers are encouraged to try Epsom salts (magnesium sulfate) or Milk of Magnesia on their skin.

One can imagine that a bath with Epsom salts would be relaxing, but …

4. Sebclair launches as Promiseb Cream

I was alerted to the launch of a product called Promiseb by a comment left on the Sebclair for Seborrheic Dermatitis post. Since then the news web sites are also covering the press release. Promiseb (probably pronounced Promi-seb) is launching in the U.S. via Promius Pharma, after being licensed from Sinclair Pharma in 2007….

Rosacea News September 2009

1. Oracea worth $104m a year, good news for Sansrosa

According to a press release via Reuters, sales of Oracea were approximately $104 million for the twelve-month period ending July 2009. This figure is up almost 200% from the previously reported sales of $52.5 million in …

2. Impax Laboratories joins the generic Oracea battle

September 21st, 2009, by Digital Davo | oracea, patents | Edit

In a further confirmation that the low dose doxycycline market is a becoming a fighting ground, a recent press release states that Impax Laboratories has filed “Abbreviated New Drug Application ("ANDA") containing a paragraph IV certification for a generic version of ORACEA with the U.S. Food & Drug Administration ("FDA").” This is a challenge to the patents held by Galderma, relating …

3. PSF reduces the pain of Pulsed Dye Laser

This just published abstract from Lasers in Medical Science, shows that the extreme pain associated with pulsed dye laser, when used to treat port wine stains, can be relieved by using Pneumatic Skin Flattening (PSF). Pneumatic Skin Flattening uses a vacuum to compress the skin underneath the area being treated. Blood is eliminated from the treatment area. The technique is said …

4. FDA gets tough with Aczone

The FDA has issued a warning letter to Allergan, the makers of Aczone for overstating the efficacy of Aczone and also for understating the possible side effects. In a sign that the FDA is watching carefully the claims that vendors use when advertising their products, the warning letter calls out a journal advertisement for Aczone as violating the Federal Food, Drug, and Cosmetic Act. …

Rosacea News August 2009

Rosacea News August 2009

1. water soluble sunscreen anyone ?

An interesting looking patent application proposing a water based sunscreen for rosacea sufferers has surfaced at the USPTO. Many rosacea sufferers will know the trauma of finding a sunscreen that is gentle enough to not cause a bad reaction and effective enough to protect from the harm of the sun. For me the sun has always been my worst trigger. Certainly physical sunscreens …

2. so does acupuncture work, or not ?

For me acupuncture has always been part of some kind of ancient mythology. Humans are controlled by a brain that has complex neurological pathways to all corners of their bodies. Can inserting fine needles in to the so-called meridians along energy …

3. Epsom salts or Milk of Magnesia actually works ?

A few newspapers have picked up this Question & Answer article where rosacea sufferers are encouraged to try Epsom salts (magnesium sulfate) or Milk of Magnesia on their skin.

One can imagine that a bath with Epsom salts would be relaxing, but …

4. Sebclair launches as Promiseb Cream

I was alerted to the launch of a product called Promiseb by a comment left on the Sebclair for Seborrheic Dermatitis post. Since then the news web sites are also covering the press release.

Rosacea News July 2009

Rosacea News July 2009

1. Doxium being trialled as Pulsed Dye Laser adjunct

A new trial is recruiting participants to evaluate the use of calcium dobelisate as a combination therapy, along with Pulse Dye Laser to treat the erythema, flushing and telangectasia associated with erythematotelangietatic rosacea. We know from rosacea and doxium that “Calcium dobesilate is a vasoactive drug with presumed effects on endothelial integrity, capillary permeability and blood viscosity.” Clinical Trial …

2. Calling all Rosacea Researchers: get your grants now !

The National Rosacea Society is calling for grant applications for their 2010 allocation. Good to see that they want an emphasis on research into the cause rosacea. From New Grants Available Monday, July 27, 2009 New grants are available from the National Rosacea Society (NRS) to support research on potential causes and other …

3. Abstracts: Elidel, Bacteria & Ocular prevalence

The following abstracts don’t deserve a Rosacea News item on their own, but are interesting enough to give a mention here in this Abstract Roundup. Elidel no better than Metrogel for lumps and bumps of rosacea. A comparison of metronidazole 1% cream and pimecrolimus 1% cream in the treatment of patients with papulopustular rosacea: a randomized open-label clinical trial. Clin Exp Dermatol. 2009 …

4. Sol-Gel Trialling Benzoyl Peroxide (DER 45 EV) for Rosacea ?

An intriguing Clinical Trial has been listed on the ClinicalTrials.gov web site. The product know only as DER 45 EV Gel (in strengths of 1% and 5%) has been listed in a dose-range trial for the papules and pustules of rosacea. Clinical Trial NCT00940992, A Dose-Range of DER 45-EV in Treatment of Rosacea (SGT-EBPO1-09) …

5. we’ve all been exposed to demodex bacteria proteins ?

An article published today in the Irish Times takes one more step in the direction of showing an association between demodex mites and rosacea. Readers of Rosacea News will know that a lot of research has tried to find a causative link between the presence of demodex mites and rosacea symptoms. Some progress towards a link between the two was …

6. acupuncture, yoga, hat and moisturiser says Daily Mail

We are seeing more and more newspaper health and beauty articles that relate to rosacea. Today the UK’s MailOnline has an intriguingly titled article – How waggling my feet has helped my red face. To save you …

7. accutane and drinking alcohol – no problem, apparently

This just published abstract is suggesting that it appears to be safe to consume alcohol while taking accutane. Whilst the Accutane Prescribing Information does not prohibit the consumption of alcohol, it does suggest that alcohol …

8. CeraVe Hydrating Cleanser and CeraVe Moisturizing Lotion User Reviews

Recently the manufacturers of Finacea, Intendis, and Coria Laboratories, have begun promoting a new combination package it is calling Finacea plus. This package encourages rosacea sufferers to combine a tube of Finacea with CeraVe Hydrating …

9. Restasis (cyclosporine) as ocular rosacea treatment

It is good to see more published research backing topical cyclosporine (Restasis, Allergan) as a treatment for ocular rosacea. Restasis (cyclosporine ophthalmic emulsion 0.05%) has been shown to increase tear production and improve the quality of naturally produced tears and is …

Rosadyn Vasculokinetic and Skin Health Support

The Rosadyn site is full of scientific terminology.

Addresses all symptoms of Rosacea: Facial Redness and flushing skin inflammation and sensitivity inflammatory bumps and breakouts.

Advanced non-prescription oral nutraceutical for vascular, ocular and skin support

Targets the root precursors of facial redness, inflammation and flushing.

Developed by Dr. Geoffrey Nase PhD., Rosacea Specialist and Researcher.

Further claims about Rosadyn: advanced pharmaceutical-grade nutraceutical, vasculokinetic, Absorption Enhancement Blend, Hypothalamus Support, Hypothalamic overdrive.

Rosacea News June 2009

Rosacea News June 2009

1. doryx + applesauce, for those who can’t swallow tablets

If you have trouble swallowing tablets, here is an official FDA sanctioned tip. Open the tablet and sprinkle the delayed release pellets on to a spoonful of applesauce. This is a good option for anyone who finds swallowing the …

2. NYTimes says no natural remedies for rosacea

The New York Times has an article today keenly titled Natural Remedies for Rosacea?. The question is one that many rosacea sufferer seek answered – are there any effective treatments for rosacea that don’t include the use of antibiotics or prescription potions and lotions ? The answer comes from one of the premier rosacea experts – Dr. Frank C. Powell. Here is an extract …

3. Favourite Over The Counter treatments

Do you have a favourite over the counter treatment for your rosacea ? Depending on your health insurance and access to doctors and pharmacies, prescription treatments are out of the reach of many rosacea sufferers. So what can you try as a rosacea treatment that is easy to source, cheap and …

4. Vita-Oil Release Next Week. Tinted ZincO in July

Here is an announcement from RosaceaCare: “Earlier this year, we announced that four important and popular rosacea products that had been unavailable for many months would thereafter, by special arrangement with the originator, be manufactured and distributed by the Rosacea Care Company. We are pleased to tell you that the first of these, the much-loved Vita-Oil, will be released and ready to ship this …

5. Is Oracea different to 50mg doxycycline ?

I came across the following graph in a recent presentation at the recent AAD meeting and figured it was interesting enough to highlight it here. The following graph, sourced from Collagenex (who sell Oracea), shows the blood plasma concentration of doxycycline after taking Oracea compared to 50mg once a day of generic doxycycline. The horizontal axis stretches out to 24 hours post dosage. …

6. Doxium (calcium dobesilate) trialists wanted

Thanks to a comment from Sophie on the post rosacea and doxium (calcium dobesilate) we know that Dr. Cuevas who is responsible for several papers on Dobesilate, is accepting people to try it as a treatment for rosacea. Thanks for the info Sophie.

7. Green Tea helps after IPL

This just published paper is suggesting that the topical application of polyphenol antioxidants (aka green tea) post IPL treatment resulted in more hydrated skin and reduced oxidative degradation of skin lipids. The authors suggest that this will enhance the effects of the IPL therapy.

Common Rosacea Mis spellings

One of the things about rosacea is that it is, well kinda spelled weird like. You can easily misspell it – especially if you hear it said, your chance of writing it correctly are pretty low.

So here we go – the most popular mis-spellings of rosacea, according to the google keywords tool ;

• rosacia
• rosecea
• roscea
• roseacea
• rosasea

I’m sure you’ll see some more in your travels too.

Rosacea News May 2009

Rosacea News May 2009

1. Dermatology Times highlights Afrin and Sansrosa

The Dermatology Times is running an article highlighting the novel and unlikely rosacea treatments based on a nasal decongestant and a glaucoma treatment. They of course are referring to Oxymetazoline and Brimonidine. The article mentions the positive results from the “most recent research” on Brimonidine ; In the most recent research, a double-blind study for Galderma, a 1 g application …

2. Ocular rosacea: oligosaccharide based treatments

An interesting looking patent that was filed in 2006 has come up as reaching filed status. This patent covers the relationship between an oligosaccharide specific to an inflammatory disease, more specifically ocular rosacea. The discovery may lead to both a definitive diagnostic test and new treatments for ocular rosacea. One of inventors of this patent is well known to rosacea sufferers. Dr. Mark Mannis …

3. Oracea too expensive ?

Some interesting comments from KUNC commentator Dr. Marc Ringel via a NPR segment. He raises two points that are worth discussing. Firstly is Oracea really any better than generic doxycycline and secondly what does it say about the pharmaceutical industry (and insurance companies – ed) that a repackaged old product  can be so expensive ? Galderma would say that Oracea is sub-antimicrobial …

4. would you like an electric current with your topical ?

A couple of recently awarded patents look both interesting and slightly scary for potential rosacea treatments. These patents cover some kind of device that is stuck to the skin. A small electric charge is used to help an active chemical cross the skin barrier. Some kind of carrier (an electrolyte) allows Zinc ions to flow between the electrodes, across the skin, creating a small charge. …

5. LED post laser helps recover from redness

A recent abstract from Dermatologic Surgery suggests that treatment with 590nm LED therapy following fractional laser skin resurfacing helps patients more quickly recover from the post treatment erythema. Whilst skin resurfacing with a laser is considered dangerous for rosacea sufferers, the fact that LED therapy help speed up recovery is good news for LED and low level light therapy in general. The study showed that …

6. novel tetracycline from Warner Chilcott and Paratek

Some very preliminary internet crumbs about a new possible rosacea treatment under development. The treatment under development is listed as a “novel tetracycline”. Warner Chilcott Limited calls itself a “specialty pharmaceutical company, that engages in the development, manufacture, marketing, and sale of branded prescription pharmaceutical products in women’s healthcare and dermatology segments primarily in the United States”. In the WCRX 2007 Annual …

7. Botox for neural symptoms and flushing, user reviews

Some interesting discussions from both experts and users of botox treatments for rosacea have are emerging online and are worth reviewing. A quick search on Google shows that several clinics are now offering botox as part of their rosacea treatments. Better known for it’s cosmetic use, the highly toxic protein known …

8. Glyco Mira developing anti-cathelicidin treatment ?

A brief paragraph in a recent article in The Salt Lake Tribune looks quite interesting. A company called Glyco Mira (seemingly a company without a web site) is developing a drug that “may be able to cure the underlying problem that causes rosacea”. A pretty tall prediction for sure. So what are they talking about ? Glyco Mira have licensed and anti-inflammatory drug from the …

Rosacea News April 2009

Rosacea News April 2009

1. Pyratine XR launches, user reviews

fact sheets, in the news, kinerase, moisturizers, topicals, user reviews

Showing just how important the internet is becoming for marketing new cosmetics, Pyratine XR has recently launched with a lot of press activity. As well as Senetek’s press releases on the internet I was also contacted by 2 …

2. Video Tips from Rosacea Rescue Squad

in the news

The Galderma rosacea promotional site Best Face Forward has a new section titled Rosacea Rescue Squad. The site features some video tips from Dr. Hilary Baldwin and Charla Krupp. Dr. Baldwin, who is a dermatologist from …

3. moisturize before or after finacea - it doesn’t matter

finacea, moisturizers, topicals

Well here you are, one of the frequently asked questions about rosacea topicals has been answered. Does it matter whether I apply my rosacea prescription topical before or after I use a moisturizer ? This recently available abstract suggests that in fact it doesn’t matter. The study looked at the absorption of finacea before and after moisturizer lotions were applied and was unable …

4. GlaxoSmithKline to buy Stiefel (Rosac/Rosasol)

in the news, topicals

Continuing recent consolidations in the pharmaceutical industry is the report that the giant GlaxoSmithKline (or GSK) are to purchase Stiefel. Stiefel is the manufacturer of …

5. AAD: oxymetazoline, dapsone and light therapy

in the news

As promised in my 67th AAD Meeting SFO, rosacea highlights news item, here are some updates from the conference proceedings and handouts. In this update we’ll look at how Dr. Downie mentions the new and future possible treatments for rosacea. This is encouraging, to see dermatologists discussing what is new and potentially interesting in the field of rosacea. SYM S048, Treatment …

6. AAD: off-label and future rosacea treatments

in the news

As promised in my 67th AAD Meeting SFO, rosacea highlights news item, here are some updates from the conference proceedings and handouts. In this update we’ll look at a couple of slides from Dr. Thiboutot.

Rosacea News March 2009

Rosacea News March 2009

1. ZENMED User Reviews

Those who have been around on the internet for a while won’t have failed to notice ZENMED. ZENMED (they use all capitals) are good at advertising and have a high profile through their advertising campaigns. In fact because Zenmed use Google Adwords you can sometimes see advertisements for them here on rosacea-support.org. When you have a company that you don’t know much about, but has …

2. AAD: natural ingredients have a role in rosacea therapy

As promised in my 67th AAD Meeting SFO, rosacea highlights news item, here are some updates from the conference proceedings and handouts. In this update we’ll look at how Dr. Downie suggests that natural ingredients do have a role in the treatment of rosacea. It is encouraging to see these complementary ingredients feverfew, green tea and licorice getting some mainstream …

3. IPL pain and no gain: Telegraph Health & Well Being

The UK newspaper The Daily Telegraph has a short fluff piece on IPL. As is usually the case with this style of article there is little substance. The reporter was not impressed with the results but was impressed with the pain and bruising and swelling. Intense Pulsed Light (IPL): miracle cure or waste of money? It is …

4. Galderma suing Mylan Pharmaceuticals over Oracea

Galderma, the makers of Oracea are suing Mylan Pharmaceuticals for allegedly infringing 4 patents related to their sub-antimicrobiotic dose doxycycline product Oracea. State University of New York, Galderma Sue Mylan March 20 (Bloomberg) — The State University of New York, Galderma Laboratories LP and New York University sued generic- drug maker Mylan Pharmaceuticals Inc. for allegedly …

5. Sun linked to rosacea, but which came first ?

The NRS have an entry up on their weblog discussing the link between sunburn and rosacea. A study of 65 healthy subjects and 65 moderate to severe rosacea sufferers found that the rosacea patients `had significantly higher rates of blistering sunburns that those without rosacea’. Sadly there was no conclusion as to whether the extra incidence of sunburn contributed to the severity of …

6. Sansrosa composition revealed in patent application

A new sansrosa patent application has appeared, and from it was can see clearly what formula will be used for the sansrosa gel and sansrosa cream formulations. We don’t know the official name for the product yet, but it seems to make sense to me to call the product Sansrosa Gel and Sansrosa Cream.

Those following the development of sansrosa closely will be encouraged by this …

7. Rosacea Expert Series: IPL & Laser

Continuing our Rosacea Expert series, the Rosacea Support Resource Pages now has a summary of the ongoing Ask a Doctor IPL & Laser sub-forum. Have a read of Laser & IPL: Dr. Peter Crouch, MB.BS, Dr Steve Johnson, MD, Dr. Nicholas Soldo, MD to find out more about the following questions; ACCUTANE WITH RED LIGHT …

8. ho hum: finacea + oracea vs. metrogel 1% + oracea

The Clinical Trials register has listed a new trial for papulopustular rosacea. The trial, sponsored by Intendis, the manufacturer of Finacea, wants to compare the combination of Oracea and Finacea, with the combination of Oracea and Metrogel 1%. It seems clear from this that Intendis would like to position Finacea as a viable alternative to Metrogel. This makes good sense …

9. 67th AAD Meeting SFO, rosacea highlights

The 67th Annual Meeting of the American Academy of Dermatology is due to meet this week in San Francisco. I have to say that the AM09 Program looks a little uninteresting for those following rosacea developments. The program contains a few advertisements from Finacea, the new Instant Relief Mineral Powder from the Clinique Redness solutions range and also Aczone …

Rosacea News February 2009

Rosacea News February 2009

1. NRS Awards 2009 Research Grants

The National Rosacea Society have just announced their 2009 research grants. Four studies have been chosen, totally almost $90,000. Quite a buzz for me to see that a study in Australia has made the grade. Dr. Richard Gallo, who has received a lot of press coverage from the research on the role of cathelicidins, and …

2. Tropisetron (Navoban): rosacea patent filed by Galderma

My regular patent trolling has unearthed something potentially interesting. The anti-nausea drug Tropisetron is patented by Galderma as a treatment for inflammatory skin conditions including rosacea. Tropisetron is officially known as a 5-HT3 receptor antagonist or a serotonin antagonist. Serotonin (5-HT) is found widely distributed throughout the gut and the central nervous system ADMINISTRATION OF TROPISETRON FOR TREATING INFLAMMATORY SKIN …

3. seborrheic dermatitis: state of the art, finacea 3 stars

This paper summarises the current state of the art for seborrheic dermatitis – research and treatment options. The author mentions recent research that links seborrheic dermatitis with a spore known as Malassezia Globosa. He makes the point that azelaic …

4. ZincO, Vita-Oil and Oatmeal Cleanser available again soon

Following is an announcement from Rosacea Care. EXCITING NEWS We have just received word that four products that have been important to many rosacea sufferers will be available again later this spring. By arrangement with the originator of these products, the Rosacea Care Company will be manufacturing and distributing ZincO, Tinted ZincO, …

5. L’Oréal strong sales via Galderma and dermatology

L’Oréal has just posted its 2008 Annual Results. The results show that L’Oréal has had a good year, mostly because of the excellent performance of Galderma. It may come as a surprise to many to know that Galderma, the …

6. Sebclair / Atopiclair available in Australia

It looks like Australians can easily get this preparation via mail and pay via paypal.

It appears to be called Atopiclair and is available from
http://www.atopiclair.com.au/ It is listed as Atopiclair Cream 40ml and is $49 including postage to anywhere in Australia.

7. Vectical (topical Vitamin D3) approved for Psoriasis

The FDA has recently approvedVectical (topcial vitamin D3 from Galderma) for the treatment of plaque psoriasis. The active ingredient of Vectical is known as calcitrol and is a naturally occurring form of vitamin D3. Calcitrol has been shown safe to use for extended periods up to 52 weeks and also on sensitive skin fold areas. Users of Vectical should avoid exposure to the sun.

Rosacea News January 2009

1. Top 5 ways to save money treating rosacea

Distressed with the expense of exotic rosacea treatments ? The stress of rosacea is enough without also having to worry about how to afford treatments. Finding affordable rosacea treatments is a real challenge. Here are my top 5 suggestions for …

2. afamelanotide positive Phase III results for erythropoietic protoporphyria

Clinuvel has  announced positive interim Phase III results from the first of the trialists to complete a 12 month study in Switzerland. The 14 patients in Switzerland will form part of 101 to undergo long term study around the world. Further participants and …

3. do naturopathic treatments work for rosacea ?

What are the best known naturopathic treatments for rosacea, and how well have they been shown to work ? Naturopathy is a medical philosophy that tries to improve our health by helping the body’s own ability to recover from illness …

4. Medicis readies to trial Ziana for rosacea

Just posted on the clinicaltrials.gov database is an entry “Safety and Efficacy Study of Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel to Treat Rosacea”. This topical product, known as Ziana, is currently approved for the treatment of acne.

5. Sansrosa has neuro protective properties

We know from patent filings that the active ingredient in the in-development sansrosa product is brimonidine tartrate. This is also the active ingredient in Alphagan P, a treatment for glaucoma.

Alphagan P 0.1%, is known as an alpha2-adrenergic receptor agonist, and is used to lower intraocular pressure and reduce ocular hypertension. Around 10-20% of users of Alphagan P experience adverse side …

6. Vote for your most wanted Linda Sy product

Good news for those wanting to be able to purchase Linda Sy products again. There is some possibility that a selection of her rosacea products will be sold through another online skin care provider.

7. Rosacea Support: 2008 the year that was

Time for some end of year statistics – for those who like that sort of thing.

Before we kick off just a note. The most important thing is that thousands of people have found useful information about rosacea. May this continue to be the case into 2009.

Top 5 ways to save money treating rosacea

Distressed with the expense of exotic rosacea treatments ? The stress of rosacea is enough without also having to worry about how to afford treatments. Finding affordable rosacea treatments is a real challenge. Here are my top 5 suggestions for building your rosacea-beating regime while on a budget.

Do you have any recommendations for your fellow rosacea sufferers that are on a budget ?

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Rosacea News December 2008

Rosacea News December 2008

1. Epidermal Growth Factor (EGF) patent application published

Artist has mentioned in the past that she has been associated with a patent to do with treating rosacea. Her involvement with SkinActives led her to investigate using Epidermal Growth Factor  (EGF) to treat rosacea. The success she experienced led SkinActives to subsequently file a patent. This patent has now reached the application status and can be viewed at the USPTO web site

2. BHA, veinwave, human placenta cream gets plugged by The Times

The UK newspaper The Times has a plug for veinwave, human placenta treatments and beta hydroxy acid for treating rosacea. This article is an update to a previous article also featuring rosacea sufferer Allie Todd. The January 26 article was …

3. Dry Eye Syndrome from Sunday Times Sri Lanka

The Sunday Times in Colombo has a recent article devoted to Dry Eye Syndrome titled Looking through a dry lens, an interview with Consultant Ophthalmologist Dr. Charith Fonseka from the Eye Hospital in Colombo. "Dry eye syndrome is usually due to a problem with the quantity …

4. MJF and Parkinson’s disease: if only rosacea had such a benefactor

A really interesting piece in the New York Times about how Michael J Fox is the front man for a revolutionary foundation fighting Parkinson’s Disease. The Michael J. Fox Foundation for Parkinson’s Research has funded an amazing $125m in research. From Taking Science Personally; What makes the story of the Michael J. Fox Foundation different — nay, what makes …

5. OCuSOFT Lid Scrub Plus kills demodex mites. Really ?

Here is a good example of why not to believe everything you read on the internet. Today the internet news stream has a `release’ titled OCuSOFT(R) Lid Scrub(TM) PLUS Proven to Kill Demodex Mites. In …

6. treating rhinophyma (large swollen nose) with ER:YAG Laser

Did you know that the first known rhinophyma surgery was performed by Daniel Sennert in 1629 ? Were you also aware that the proven link between rosacea and rhinophyma was established in 1846 ? Rhinophyma and rosacea sure have …

Rosacea Support: 2008 the year that was

Rosacea Support Blog

Time for some end of year statistics – for those who like that sort of thing.

Before we kick off just a note. The most important thing is that thousands of people have found useful information about rosacea. May this continue to be the case into 2009.

Unique Visitors to rosacea-support.org: 489,098

Page Views on rosacea-support.org: 1,682,675

Blog Posts and Pages: 375

Comments left on Blog: 1012

Top 5 Blog Pages:

1. Photos of Red Nose, Papules, Pustules, acne like rosacea
   
2. how to cure a red face (facial erythema or redness)
   
3. demodex mites treatment
   
4. Eucerin Redness Relief: product reviews
   
5. Clinique Redness Solutions: user reviews

Most Commented Posts:

1. lindasy.com is closing down  (62)
   
2. how to cure a red face (facial erythema or redness)    (52)
   
3. Periostat (doxycycline) goes generic, get ready for Oracea   (49)
   
4. focus on metronidazole (metrogel)    (47)
   
5. Australia (46)

Rosacea Support Resource Pages

Unique Visitors to Rosacea Support Resource Pages: 41,921

Page Views on Rosacea Support Resource Pages: 95,585

Rosacea Support Email Group

Emails posted to rosacea-support@yahoogroups.com: 3842

Rosacea Support Community Forum

Messages posted to Rosacea Support Community: 5,015

I wish everyone a great 2009. May this year be one that you look back on with fondness and with satisfaction at moving forward in your life.

warmest regards,

David Pascoe.

Rosacea News November 2008

1. are you a cyberchondriac ? the dangers of the internet

Self diagnosis using search engines can lead to internet users concluding the worst about their ailments. So says some recent research from Microsoft. The researchers looked at health related web searches and also surveyed employees of Microsoft. This study is thought to be the first systematic look at the anxiety of people doing web searches related to health care. A couple of the examples …

2. IPL burns from `Top London Spa’

The Independent newspaper in the UK has an article today in their Health & Wellbeing section detailing (seemingly) a reporter who was badly burned by an IPL treatment. The photos show large uneven red welts on her chest and areas of redness on her face also. The initial treatment was carried out by …

3. RosaceaCare Cool Relief Mask Samples available

The guys at RosaceaCare have sent me some samples of their new Cool Relief Facial Mask. Their web site promotes this product as a cooling  mask that “contains many of the ingredients that have proven so successful in our other products: Willowherb Extract, Green Tea Leaf Extract, Jojoba Seed Oil, Allantoin and …

4. cinnamon supplements may make rosacea much worse

Apparently cinnamon oil supplements are commonly used by sufferers of type 2 diabetes to reduce their blood sugar and cholesterol levels. One study from Pakistan concluded that cinnamon taken at 1, 3, or 6 gm daily significantly decreased the …

5. UK Warns about Melanotan usage

The mainstream UK press has several articles today about the risks of an using a yet to be approved injectible tan, even go so far as to name Melanotan. The Independent: Warnings over ‘injectable tan’ product People seeking a glow this winter should avoid an "injectable tan" being sold illegally, regulators warned today. The Medicines …

6. How to cure a red swollen nose

The red swollen nose of rosacea is a much hated symptom. I know that this was the symptom that I despised most and indeed drove me 10 years ago to start to look for good information about how to treat rosacea. …

7. DermatologyTimes on LED and IPL Combination Therapy

From the Nov 1, 2008 edition of DermatologyTimes; Synergistic effect: Combining LED devices with PDL or IPL optimizes rosacea treatment Combination laser and light-based treatments for rosacea have a synergistic effect and are now being studied, according to David J. Goldberg, M.D., a board-certified dermatologist in practice since 1985 at Skin Laser & Surgery Specialists of New York and …

8. DermatologyTimes: Sansrosa not available for several years

Dermatology times has posted some short items that may be worth reading. Most of these topics are not new to regular readers of Rosacea News, but it is good to see at least some others covering them as well. One article talks about how Galderma/Collagenex is excited about new possible drugs. It doesn’t directly name the Sansrosa product, but it does have a …

Rosacea News September + October 2008

1. lindasy.com is closing down

Just in case anyone has missed the email over at rosacea-support; Linda Sy has been in contact to say that she is retiring and thus her web site and business is closing. Anyone who wants to stock up on their favourite products will need to order some now as they will no longer be available after the end of October, or as long as stock lasts.

2. contact lenses and ocular rosacea, tips and advice

The NRS Ask the Doctors blog section has a post up today with some advice about ocular rosacea and using contact lenses.

`What guidelines should I follow regarding contacts if I have ocular rosacea? Response by Dr. Marian Macsai, vice chairman of ophthalmology at Northwestern University.’

3. how to reduce your visible pore size: NRS Blog

The NRS Ask the Doctors has a new post up asking Rosacea has made the pores on my face large. When I get my rosacea under control, will my pores return to their normal size? Topical and oral antibiotic therapy may be prescribed for mild cases, but more severe cases may sometimes be treated with isotretinoin, which is an …

4. NRS acknowledges children can get rosacea

The latest instalment of the NRS Ask the Doctors blog addresses the possibility of children suffering from rosacea. Dr. Paller says that the published literature does mention cases of rosacea being found in children, although it is rare. The possibility of childhood ocular rosacea is also mentioned. My wife believes that our 10-year-old son might have rosacea. She is a sufferer, and …

5. Photoprotection expertise from Clinuvel

Perhaps Clinuvel is best known as the Australian company that is developing Afamelanotide. As some background: Melanotan is the proprietary name for afamelanotide (CUV1647) which is being development by Clinuvel Pharmaceuticals. Afamelanotide has been designated by the world health organisation as the International Nonproprietary Name for the melanocyte stimulating hormone under development by Clinuvel. Clinuvel is promoting this drug as a …

6. NRS on seborrheic dermatitis

The National Rosacea Society web site has just uploaded a page on Seborrheic Dermatitis ; Although the two disorders are unrelated, a recent clinical study found that 26 percent of patients with rosacea also had facial seborrheic dermatitis and 28 percent had seborrheic dermatitis of the scalp. Additionally, a survey by the National Rosacea Society of 1,100 rosacea patients found …

the red nose of rosacea

The red swollen nose of rosacea is a much hated symptom. I know that this was the symptom that I despised most and indeed drove me 10 years ago to start to look for good information about how to treat rosacea. Incidentally, this drive lead to the creation of the internet based Rosacea Support Group in 1998.

Here are my notes on how to cure a red swollen nose

Rosacea News August 2008

1. Handheld OMNILUX clear-U, red and blue LEDs together

Blue light in combination with red light has been shown to be effective in the treatment of acne. It has been proposed that the 2 colours act together synergistically to combine their antibacterial and anti-inflammatory actions. This paper looks at the handheld unit called the Omnilux clear-U (from Photo Therapeutics). This unit has a flat plane measuring, 60mm x 50mm, consisting of LEDs emitting light at wavelengths of blue light; 415nm (at 40mW/cm2) and red light; 633nm (at 70mw/cm2). The unit allows you to switch between the red and blue modes of operation.

2. topical vitamins A, C, E and B3

Vitamins A,C, E & B3 are found naturally in the skin and have been shown to have potent anti-inflammatory and anti-oxidant properties. They can be depleted by sunlight, smoking, pollution and other free radical stress. The number of products containing these vitamins has ballooned in recent years. Read on to see how the theory and background of these Vitamins might be good for you.

3. natural anti-inflammatory therapies

Dr. Wu published a paper in 2006 on treating rosacea with herbs. This paper highlighted the properties and potential rosacea treatment modalities of licorice, feverfew, green tea, oatmeal, lavender, chamomile, tea tree oil and camphor oil. This just published paper concentrates more on the anti-inflammatory properties of several natural products and reviews the evidence supporting their use in inflammatory skin conditions.

4. colloidal oatmeal: a dream ingredient for rosacea sufferers

Colloidal Oatmeal is a versatile and multi-functional compound. This paper details the history and chemistry of colloidal oatmeal and shows how its’ chemical polymorphism leads to many useful clinical properties. Of most interest to rosacea sufferers are the cleansing, moisturizing, buffering, soothing, protecting and anti-inflammatory properties. Colloidal Oatmeal may well be the dream ingredient for rosacea friendly products.

5. oxymetazoline may be good for 2 years

The dermatology news sheet Dermatology Times has published an item to their web site about the emerging use of oxymetazoline to treat the redness and flushing associated with rosacea. This article draws from the Nov. 2007 paper that introduced us to the possibility of treating rosacea with oxymetazoline.

6. just how do you kill demodex mites ?

Demodex mites and rosacea seem to be a popular pairing. If you are interested in eliminating demodex mites to see if your rosacea symptoms improve, just how can you kill them ? Demodex mites are tiny, and live naturally in everyone’s skin. They are quite difficult to kill. Read on if you’d like to know more.

natural anti-inflammatory therapies

Many rosacea sufferers want to treat their symptoms with natural therapies. This pursuit can be tricky as many natural ingredients are not easily obtained in a useable form. In the end it is sometimes just down to using commercial preparations that contain the active ingredient – and hopefully at the same time no other potentially irritating components. Another option is to try natural ingredients using a homemade mix.

Find out more about turmeric, colloidal oatmeal, feverfew, licorice, chamomile, and aloe vera in the natural anti-inflammatory therapies article.

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• ocular demodex, tea tree oil as a treatment
• golden chamomile
• lavender, arnica, aloe vera, tea tree oil, and calendula ; do they work ?
• US Pharmacist: Anti-inflammatory Herbs discussed here.

colloidal oatmeal: a dream ingredient for rosacea sufferers

Colloidal Oatmeal is a versatile and multi-functional compound. This paper details the history and chemistry of colloidal oatmeal and shows how its’ chemical polymorphism leads to many useful clinical properties. Of most interest to rosacea sufferers are the cleansing, moisturizing, buffering, soothing, protecting and anti-inflammatory properties.

click to read more about how Colloidal Oatmeal may well be the dream ingredient for rosacea friendly products.

 

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• Linda Sy Mild Oatmeal Facial Cleanser
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oxymetazoline may be good for 2 years

The dermatology news sheet Dermatology Times has published an item to their web site about the emerging use of oxymetazoline to treat the redness and flushing associated with rosacea. This article draws from the Nov. 2007 paper that introduced us to the possibility of treating rosacea with oxymetazoline.

Oxymetazoline is classified as a alpha-1 Adregenic Receptor Agonist, whereas COL-118/Sansrosa is a alpha-2 Adregenic Receptor Agonist. According to this DT article oxymetazoline is “also partially selective for the alpha 2a receptor.”

(click to read more about oxymetazoline may be good for 2 years )

Related Articles

• Sansrosa’s sister to enter redness race
• oxymetazoline good for 6 hours and safe for 3 months
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Afamelanotide (Clinuvel CUV1647) gets orphan drug status in the US

Afamelanotide (Clinuvel CUV1647) gets orphan drug status in the US

Clinuvel Pharmaceuticals has announced that they have been granted orphan-drug status by the FDA to treat the skin condition erythropoietic porphyrias. Orphan drug status is granted to new drugs that treat rare conditions and is used as an instrument to obtain accelerated review by the FDA. The FDA allows tax reductions and market exclusivity for orphan drugs to encourage otherwise un-profitable drugs targeting rare conditions to be developed.

• Afamelanotide (Clinuvel CUV1647) gets orphan drug status in the US
• melanotan (epitan) offers sun protection for fair skin individuals
• Clinuvel trialling CUV1647 (melanotan) for skin cancer for transplantees

Read more about: melanotan

Rosacea News July 2008

1. Afamelanotide (Clinuvel CUV1647) gets orphan drug status in the US

Clinuvel Pharmaceuticals has announced that they have been granted orphan-drug status by the FDA to treat the skin condition erythropoietic porphyrias. Orphan drug status is granted to new drugs that treat rare conditions and is used as an instrument to obtain accelerated review by the FDA. The FDA allows tax reductions and market exclusivity for orphan drugs to encourage otherwise un-profitable drugs targeting rare …

2. EC approves Oracea for sale in Europe

The news sites are buzzing with the announcement that the European Commision has granted marketing authority for Oracea. The first domestic approvals for Oracea will be granted in Germany, UK, Italy, Austria, Ireland, Sweden, Finland, Luxembourg, and the Netherlands. MediGene has the rights to sell Oracea throughout Europe. Local approvals are expected within 30 days. This news follows on from the announcement …

3. rosacea allergic reaction to Vitamin K & Vitamin E

This paper raises and interesting topic. The researchers were able to prove that 3 rosacea sufferers were allergic to alpha-tocopherol (Vitamin E) and Vitamin K. By eliminating the components of the creams they were using, they were able to isolate the individual components that were causing the allergy. Rosacea sufferers can become attuned to the ingredient listing in cosmetics, scouring the list to find something …

4. AARS publish their rosacea treatment guidelines

The American Acne & Rosacea Society have published a PDF containing their Rosacea Medical Management Guidelines. The aim of the guidelines is  “to provide an overview of the fundamental disease state of rosacea and quality of life implications and outline available pharmacological …

5. rosacea sufferers have more anxiety and depression

In the past there hasn’t been a lot of research into the relationship between rosacea and mental health. Many rosacea sufferers know that there is a strong relationship between their symptoms and how they feel about themselves. This abstract mentions some research comparing rosacea sufferers with people without any facial lesions. They found that the rosacea sufferers had several psychological problems not found …

6. demodex bacteria, one baby step at a time

Some recent NRS supported research has made more steps towards showing a possible link between demodex mites and rosacea symptoms. Although this Br J Dermatol paper was mentioned by Rosacea News in (see demodex mite bacteria causes the inflammation ?) June last year, I just got hold of the full text this week.

Rosacea News June 2008

Rosacea News June 2008

1. rosacea sufferers less interested in alternative medicine

According to this recently published short correspondence, rosacea sufferers are much less likely to use complementary and alternative medicine compared to sufferers of psoriasis and other dermatological conditions. Whilst the reason is not clear, it appears one reason could be that sufferers are happy with the efficacy of their current treatment. The majority of patients felt that the complementary and alternative therapies were less helpful …

2. sensitive skin on your hands, feet and scalp too ?

The common wisdom about rosacea is that is only occurs around the flush zones on your face. A recent paper challenged this idea with a case study of a patient who had rosacea lesions on his arm, and upper chest area. Another related recent short paper titled Sensitive skin is not limited to the face, that has the conclusion that sensitive skin is …

3. NRS wants your feedback on Research !

The NRS Blog has a new entry today where they are asking for your feedback on the direction of future rosacea research. The NRS have put their Reader Survey (part of their Rosacea Review publication) online for the first time.

4. Allergan buys Aczone, has plans for rosacea targeting ?

OK this story is getting so much coverage in the online press that I thought I should cover it here too. Allergan is buying the topical dapsone product called Aczone for $150m. From: Allergan Announces Agreement to Acquire Aczone(R) Gel 5% …

5. Sansrosa gel vs. eyes drops absorption trial details posted

The Clinical Trial register is showing details for the bio-availabilty trial for COL-118/Sansrosa. This Phase 2 trial aims to compare the amount of the active ingredient that is bio-available when the newly formulated gel is used on rosacea skin, and when used as eye drops.

This announcement appears to be the extra trial asked for by the FDA who are concerned that …

Rosacea News May 2008

Rosacea News May 2008

1. combining Azithromycin with Protopic (tacrolimus) topical

This paper details a somewhat exotic combination therapy: oral azithromycin and topical tacrolimus. It offers an alternative to the more common doxycycline + metrogel combination. The authors mention that this is not a first line therapy; "a combination of oral azithromycin and …

2 Flushing: it’s all in your nerves and emotions

In November 2006 I blogged about taking part in some research at Murdoch University investigating the relationship between stress and the flushing of rosacea. Recently the researcher, Daphne Su, has thanked the trial participants by circulating a summary document. The research has been written up as a thesis so this summary was a short description of some the …

3. Low Level Light Therapy details posted

TP has posted an update to her Low Level Light Therapy- an overview thread at the Rosacea Support Forum.

This recent update is from a document called Cellular Mechanisms of Low-Power Laser Therapy.

Thanks for the update TP. This thread is worth a read for those interested in Low Level Light Therapy (LLLT) such as LEDs, infrared, red and blue light.

4. Marketing company seeks interviews in Houston, TX

Schlesinger Associates are looking for rosacea patients on Friday June 13 2008, to attend an interview for an hour at their Galleria Area location in Houston TX. Their address is 1455 West Loop South, Suite 500. …

5. Google Health Launches, rosacea is included as a condition

Google has been talking for a while about their push into health services. One of their stated features of Google Health is "Learn about health issues and find helpful resources: Review trusted information on diseases and conditions and learn about possible medication interactions and other topics to talk your doctors about." As part of their new offering Google Health has created some Condition References. …

6. does using a computer screen worsen rosacea symptoms ?

Rosacea sufferers sometimes bring up the topic of computer screens and indeed lighting in general as a trigger for their rosacea. Sadly there seems to be little conclusive literature available on this topic. A 1985 study in Norway, Does visual display terminal work provoke rosacea? was able to show that rosacea and seborrheic dermatitis sufferers were over represented in …

7. cathelicidins regulated by Vitamin D3

Another paper stemming from the partly NRS funded research into the role of cathelicidins and its role in rosacea. A lot of publicity and publications have resulted from Dr. Gallo’s research. This avenue of research into rosacea looks promising so lets hope that more resources target involved with this area of research. Those that interested in the role that Vitamin D3 play …

8. metrogel also works for seborrheic dermatitis

This paper found that 0.75% metrogel worked just as well as ketoconazole 2% cream in treating SD. The study found that both were able to offer significant improvement with similar side effects. The authors suggest that because there is so little evidence of anti fungal activity of metronidazole, it is difficult to speculate …

9. Sebclair for seborrheic dermatitis

This recently published paper investigates the effectiveness of a `novel steroid-free cream containing multiple active ingredients’, called Sebclair to treat facial seborrheic dermatitis.

This product sounds quite interesting for rosacea and rosacea/SD sufferers. Little information about Sebclair is currently available on the internet.

10. SIBO eradication clears rosacea: are you serious ?

This sort of abstract just make me shake my head. If you read quickly you will think that this abstract suggests that Small Intestinal Bacterial Overgrowth (SIBO) causes rosacea. What this abstract is saying that is that rosacea sufferers seem to have a higher incidence of SIBO than non rosacea sufferers. The secondary result is that eliminating SIBO clears rosacea. Well that is no surprise …

11. Pycnogenol Redness Reducing Serum: any reviews ?

Pycnogenol® is the patented trade name for a water extract of the bark of the French maritime pine ( Pinus pinaster  ssp.  atlantica ), which is grown in coastal south-west France. Pycnogenol® contains oligomeric proanthocyanidins (OPCs) as well as several other bioflavonoids: catechin, epicatechin, phenolic fruit acids (such as ferulic acid and caffeic acid), and taxifolin. Procyanidins are oligometric catechins found at high concentrations in red wine, grapes, cocoa, cranberries, apples, and some supplements such as Pycnogenol®.