Rosacea News September 2014

1. Galderma offers physicians advice for Mirvaso Rebound Redness

Galderma have added a page to the Mirvaso web site to guide doctors dealing with the potential for “rebound” by users of Mirvaso. This would seem to confirm that Galderma is aware that there are users of MIRVASO who are experiencing adverse events. The use of double quotes around “rebound” and “worsening” is interesting and […]

 

2. New adverse allergic contact reaction to Mirvaso noted in JAAD

The latest edition of the Journal of American Academy of Dermatology lists an exchange by letter detailing a contact dermatitis allergic reaction to Mirvaso. The adverse reaction was found by the doctors to be caused by the main active ingredient in Mirvaso, Brimonidine. The writers of the letter to the JAAD caution other doctors that […]

 

3. Laropiprant (MK-0524) fails as a treatment for a red face

We don’t often get to see research results published that show a proposed new treatment doesn’t work. It make sense that researchers and pharmaceutical companies would rather see their research and development efforts succeed and lead only to new products. A clinical trial for MK-0524, Merck’s designation for their product known as Laropiprant, has confirmed […]

 

 

4. Ivermectin better than Metrogel 0.75% for papules and pustules

Some just published research from the Ivermectin Phase III study group suggests that Ivermectin 1% cream once a day is better than Metronidazole 0.75% twice a day at treating the papules and pustules of rosacea. The British Journal of Dermatology paper tells us that although both Ivermectin and Metronidazole did lead to a reduction in […]

 

5. Rossoseq gets some publicity from the Irish Examiner

Some friendly words from the Irish Examiner recently seeking to create an Irish link to the topical treatment known as Rossoseq. According to the article Rossoseq is being made available firstly in Ireland. Rossoseq has been associated with a mild reduction in redness in a small trial of 10 users. What is Rossoseq? The product […]

 

 

6. Mirvaso Gel is now available in Australia

According to the Galderma AU web site, Mirvaso is now available in Australia. Here are the Australian versions of the MIRVASO Gel User Consumer Information and also Mirvaso Product Information. Mirvaso was first registered in the Australian Register of Therapeutic Goods on the 4th of August 2014. See the listing here – MIRVASO CMI Mirvaso […]

Rosacea News July–August 2014

1. Finacea Foam Phase III Results Announced

Bayer HealthCare has announced positive results from a Phase III trial that evaluated the safety and efficacy of a foam formulation of Finacea – 15% azelaic acid. Last we heard from Finacea Foam was results from trials in 2011 where 401 patients were trialled. This study examined how well finacea foam performed compared to the […]

 

2. Report ONRELTEA bad reactions to Canada Vigilance Program

Users of ONRELTEA in Canada who have bad reactions or `adverse events’ related to using this newly approved product are reminded in the ONRELTEA Product Monograph to report these events. The body responsible for supervising prescription drugs is the Canada Vigilance Program. The Brimonidine based topical which is available in the US as Mirvaso has […]

 

3. ONRELTEA User Reviews

Galderma, for reasons unknown, decided to rebrand the newly FDA approved Mirvaso as ONRELTEA in Canada (yes they use all capitals in the brand name). This continues the tradition for Galderma of split North American branding; Oracea in the US is known as Efracea in Canada. There is already some history of user experiences of […]

 

4. Mirvaso features in Sky TV’s My Naked Secret

Rosacea Forum user rosaceaclearwannabe has posted about a recent episode of My Naked Secret that features a participant who was treated with Mirvaso. The show follows Anna who suffers from the red face of rosacea. She is followed as she becomes one of the first people in Europe to try being treated with Mirvaso. The […]

 

5. Sansrosa suing Galderma over Mirvaso

News today that the former owners of the patent covering the product Mirvaso have sued Galderma over a contract dispute. The 5 former owners of Sansrosa say that a contract error will cost them $20m. Sansrosa, who was then owned by Collagenex was sold to Galderma in 2008. Galderma asserts a group of patents protect […]

Rosacea News April–June 2014

1. Free Prescription Samples Increase Rosacea Rx Costs

The existence of free drug samples appears to be altering the habits of doctors such that treatments are overall more expensive for patients. This is the result of some research into the prescribing patterns of a group of acne and rosacea patients in 2010. The researchers found that doctors who distributed free drug samples were […]

2. Nasalcrom regulates Mast Cells – reduces redness

In September last year a trial was listed to assess whether cromolyn sodium ophthalmic solution 4% could improve the redness associated with rosacea. This trial was listed by Dr. Anna Di Nardo, who is a part of the UCSD and has received NRS funding in 2012 to research the link between Mast Cells and the […]

3. Rutin Forte Supplement reduces redness apparently

A paper published in the Georgian Medical News, and listed on PubMed details a study that concludes that Rutin Forte is an effective means for the treatment and prevention of erythematous rosacea. The supplement was included alongside regular rosacea therapy of topical and oral antibiotics. What is Rutin Forte? Rutin Forte is a nutritional supplement […]

4. Mirvaso launches as ONRELTEA in Canada

Galderma has reached into its bag of trademarks and announced that Mirvaso will be known as ONRELTEA in Canada. Red Faced? Rosacea Sufferers Now Have a New Option Proven to Reduce Facial Redness Health Canada Approves The First and Only Topical Treatment Indicated for the Persistent Facial Erythema of Rosacea THORNHILL, ON, May 21, 2014 […]

5. Galderma’s 1% Ivermectin Cream expected later this year

Linda Stein Gold mentions in a video posted on Skin and Allergy News, referring to Galderma’s Ivermectin Cream ; Phase 3 Clinical Trials have completed, and FDA Approval is expected later this year (2014). This is great new for those who 1) want to try an approved treatment for demodex mites and 2) may not […]

6. Cliradex T4O wipes for treating Eye Lash Mites

In mid 2012 we learned that a company called Tissue Tech was going to trial single use T4O wipes as a treatment for ocular demodex mites. Early last year Bio-Tissue Inc., the parent company of Tissue Tech announced the release of Cliradex. This new product is promoted as a tea tree oil based moist towelette […]

Rosacea News March 2014

1. Skinceuticals Redness Neutralizer can help a red face

First hinted at 2 years ago at the 2012 AAD meeting in San Diego, a new topical from Skinceuticals is now available and is starting to accumulate some modest research suggesting that it is good for a red face. This paper published in the JDD suggests that using Skinceuticals Redness Neutralizer along with the regular […]

2. Mirvaso may cost £34 a tube in the UK

Following hot on the heels of the announcement that Mirvaso has been approved across Europe is an update to the UK’s NHS New Drugs website. The Mirvaso page has hinted that the cost of Mirvaso in the UK, when it launches next month, may be as low as £34  a tube. Further, a tube is […]

3. Ivermectin Cream works really well, but Nobody Knows Why!

The clinical trial data for Galderma’s upcoming 1% Ivermectin Cream product (known during development as CD5024) is looking quite good. The data is showing that Ivermectin Cream is able to effectively reduce the papules and pustules of rosacea. There may even be some hints that it has a lower adverse reaction rate compared to its […]

4. Mirvaso Rebound and Stinging Documented in JAAD

The occurrence of significant rebound redness and stinging after using Mirvaso is beginning to surface more and more in the public eye. This recent letter to the editor in the Journal of the American Academy of Dermatology describes 3 cases of severe reaction to Mirvaso. Patient 1 had “in all areas where the medication had […]

5. Cetaphil Gentle Skin Cleansing Wipes, no rinsing needed

I feel like a bit of a Galderma PR machine at the moment, but Galderma do seem to be doing a lot. Maybe this product is yet another step in Galderma’s quest  to own the Rosacea Market. So coming soon is a moist cloth version of Cetaphil Gentle Skin Cleanser. Have you ever wished that […]

6. Mirvaso launches promotional rediswrong.com web site

Galderma is ramping up its promotion of Mirvaso with the launch of a web site to promote the idea that a red face is just wrong. The site is a funnel page, attempting to direct you over to mirvaso.com. This type of web site is known as a `direct to consumer symptom awareness campaign’ – […]