Wednesday, September 18, 2013

Rosacea News April 2003

Xifaxan and SIBO Treatment of Rosacea

Another paper investigating the link between Small Intestine Bacteria Overgrowth and rosacea symptoms has recently been published. Many of the results in this 2013 letter to the editor of JAAD confirm early discoveries from the 2008 paper from Clin Gastroenterol Hepatol. The earlier paper concluded that ; This study demonstrated that rosacea patients have a […]

Wanted SF: Asian Women with Redness for Translucent Treatment Powder

Biometrix are looking for trial participants in San Francisco. This trial is looking for Asian Women with facial redness, interested in trying a `mineral treatment pressed powder’. The powder is said to visibly reduce redness on application. See below for more details. Biometrix conduct possibly relevant trials each month, so you are in San Francisco […]

PreCision Dermatology Trialling PDI-320

A slightly obscure clinical trial has recently listed, related to treating the lesions and facial blood vessels of rosacea. The drug mentioned is PDI-320, and the party conducting the trial is Precision Dermatology. What is PDI-320? If you look closely at the exclusion criteria, you see that participants are not allowed to have  “previously failed […]

Sansrosa and Afrin Updates from Dr. Fowler & Dr. Webster

Skin and Allergy News is running an article dated this week based on some informal comments from Dr. Joseph F. Fowler Jr. and Dr. Guy W. Webster given recently at the Hawaii Dermatology Seminar sponsored by the Global Academy for Medical Education/Skin Disease Education Foundation (SDEF). These comments relate to two of the hottest topics […]

Indian Pharma may allow Generic Oracea

There is always a lot going on in the world of BigPharma. A recent court case in India suggests that the Indian Government will allow local manufacturers to produce generic versions of in-patent drugs that are simple derivatives of existing drugs. India’s law restricts pharmaceutical companies from obtaining new patents for small modifications to existing […]

Rosacea News May/June 2013

Proving Sansrosa works as well as users think

A slightly unusual trial has surfaced at ClinicalTrials. The Phase 3 trial for Sansrosa seeks to prove that patients’ satisfaction with Sansrosa matches being treated with the active gel. In short, the trial wants to prove that any improvement in facial redness perceived by the trial participant can be shown to be because of Sansrosa. […]

New Demodex Treatment: MooGoo Demodectic Rosacea Powder

Came across an interesting looking new product from MooGoo – Demodectic Rosacea Powder, that appears to be available to order. The product is an innovative approach to try to eliminate demodex mites by making the surface of the skin an environment where the mites cannot survive. If this demodex-hostile environment can indeed be achieved whilst […]

Acne Bacteria causes Chronic Lower Back Pain

Seems like a solid result, showing that in patients with `slipped discs’ (prolapsed is a better term) can benefit from antibiotic therapy to eliminate Propionibacterium acnes. This bacteria is known to play a role in acne and is now believed to have a role in the inflammation of chronic lower back pain. Participants in these […]

Patent: Rapamycin / Sirolimus to treat Telangiectasia

There are very few existing rosacea treatments for the broken blood vessels and general red face of rosacea. Historically laser and IPL are the only proven treatments for this rosacea subtype. In the last couple of years rosacea sufferers have been encouraged by the development of 2 new drugs that could help treat these symptoms […]

Solodyn with and without Finacea

A recent study has highlighted the benefits of the combination therapy of Solodyn and Finacea. Solodyn is one of the lesser known systemic rosacea treatments. What is Solodyn? Solodyn is an extended-release, low dosage of Minocycline, a member of the tetracycline family. Solodyn is available in 8 strengths. Yes that is right you can get […]

Rosacea News July 2013

1. Bionect improves Rosacea Symptoms

A recent paper in the Journal of Drugs in Dermatology suggests that Bionect may be helpful for the symptoms of rosacea. The study found that after 4 weeks the burning or stinging and dryness of rosacea was much improved, while papules and redness were also improved. What is Bionect? Bionect is a prescription only cream, […]

2. Sansrosa looks to be marketed as Mirvaso

Thanks to a post from Barbara, we have learnt that a member of a German support forum for rosacea, that Galderma may be planning to market Sansrosa as Mirvaso. It is pretty brief but here is what we know so far. Re: New form of therapy! by Mary »Wednesday 27 July 2013, 08:56 Hello, I […]

3. SIG990 Gains IND Status for Rosacea Redness and Lesions

Previously known as Signum Biosciences, Signum Dermalogix has announced today that the FDA has granted them IND Status for the Isoprenylcysteine Analog known as SIG990. Investigational New Drug status means that the FDA believes that the molecule is safe enough to commence clinical trials. This means that SIG990 is moving into Phase I of is […]

4. Promiseb now available as Scalp Wash

The nonsteroidal prescription Promiseb is now available as a Scalp Wash. Available only as part of `Promiseb Complete’, Promiseb Plus Scalp Wash is said to have “earned favorable ratings from patients for Helping with the appearance of dandruff and scalp redness” What is Promiseb? Promiseb Cream is a FDA-cleared medical device and has no active […]

Rosacea News August 2013

1. Mirvaso Before and After Pictures

What sort of benefit might you expect from using Mirvaso to treat your rosacea redness? Well, Galderma has made available some publicity photographs that show before and after photographs from the Mirvaso Clinical Trials       Quite impressive, don’t you think ?   Related Articles Mirvaso (Sansrosa, Brimonidine) Approved for Rosacea Redness Mirvaso Ingredients […]

2. Skinova helps rosacea with Ultrasound Skin Treatments at home

A recently published paper introduces us to a new form of at-home therapy based on high frequency ultrasound. The Skinova treatment using sound waves at a very high frequency of 10 MHz. This allows treatments to a depth of around 0.3cm. At this depth we are told that “the effect is mainly concentrated on the […]

3. Mirvaso Ingredients

The just approved Mirvaso is a milestone in the long development and approval process. Rosacea sufferers have watched this drug since as early as 2004 when patents started emerging. Now that Mirvaso has been officially approved by the FDA more information about the final formulation has emerged. From the Mirvaso Prescribing Information we can see […]

4. Mirvaso Ingredients

The just approved Mirvaso is a milestone in the long development and approval process. Rosacea sufferers have watched this drug since as early as 2004 when patents started emerging. Now that Mirvaso has been officially approved by the FDA more information about the final formulation has emerged. From the Mirvaso Prescribing Information we can see […]

5. Mirvaso (Sansrosa, Brimonidine) Approved for Rosacea Redness

News today that Galderma has succeeded in gaining FDA Approval for Mirvaso – the brand name chosen for the product that during development was known as Sansrosa, CD07805/47 and Col-118. The Brimonidine Tartrate 0.33% Topical Gel is expected to be available as soon as next month. Great news that approval has been granted after so […]

6. Step backwards for Generic Oracea. Invalid patents are back

For those following the saga of the possible availability of Generic Oracea in the future, another twist today. Two of the patents that were previously ruled invalid and thus unable to protect Galderma’s product, have now been ruled no longer invalid. This legal ruling will no doubt embolden Galderma that their profitable product Oracea can […]

7. Patent: Combining Sansrosa and Finacea

Galderma is staking out its claim on potential rosacea topicals with another patent being published. This patent details potential topicals that are combinations of the active ingredients in Sansrosa and Finacea, namely Brimonidine Tartrate and Azelaic Acid. The touted benefits from combining the two actives is a reduction in rebound redness and a greater tolerance […]

8. Generic Oracea one step closer, Lupin gets Tentative FDA Approval

News today that Lupin has been granted tentative approval by the FDA to product a generic version of Oracea. We learn in 2010 that Lupin had filed an abbreviated new drug application to make generic Oracea. Lupin Pharmaceuticals, based in Mumbai India,  is a company specialising in the production of generic medicines. It has been […]