Tuesday, May 18, 2010

Scenesse now available in Italy

afamelanotide

Clinuvel has announced today that Italy has pre-empted the approval of Afamelanotide (Scenesse) by the FDA in the US by approving it for the treatment of erythropoietic protoporphyria (EPP).

Despite the relatively small number of participants in the Italian trial to treat EPP, and the small number of EPP sufferers thought to directly benefit from this therapy, the approval by Italian Medicines Agency (AIFA) is significant because it confirms Afamelanotide’s efficacy and safety and also that national medicine agencies are willing to rapidly approve afamelanotide.

Clinuvel have also announced that afamelanotide will be marketed under the brand name of Scenesse (pronounced “sen-esse”). From today onwards, Clinuvel will adopt SCENESSE in all references to the drug in its further global clinical development.

Related Articles

Scenesse now available in Italy

afamelanotide

Clinuvel has announced today that Italy has pre-empted the approval of Afamelanotide by the FDA in the US by approving it for the treatment of erythropoietic protoporphyria (EPP).

Despite the relatively small number of participants in the Italian trial to treat EPP, and the small number of EPP sufferers thought to directly benefit from this therapy, the approval by Italian Medicines Agency (AIFA) is significant because it confirms Afamelanotide’s efficacy and safety and also that national medicine agencies are willing to rapidly approve afamelanotide.

Clinuvel have also announced that afamelanotide will be marketed under the brand name of Scenesse (pronounced “sen-esse”). From today onwards, Clinuvel will adopt SCENESSE in all references to the drug in its further global clinical development.

Related Articles

Thursday, May 06, 2010

Rosacea News April 2010

Rosacea News April 2010

1. Gut Bacteria and Xifaxan get some press coverage

April 30th, 2010, by David Pascoe

The St. Louis-Dispatch has an article today exploring the link between the overgrowth of small intestinal bacteria and rosacea symptoms for some rosacea sufferers. New way to treat skin disorder By Cynthia Billhartz Gregorian, ST. LOUIS POST-DISPATCH, 04/29/2010 … Weinstock is not a dermatologist. He’s a founding partner …

2. Ocular symptoms match Demodex Bacteria reaction too

April 29th, 2010, by David Pascoe

This paper is one more small achievement using statistics to try to build a picture of how demodex mites might be involved with rosacea symptoms. We have learnt from recent research that rosacea sufferers are sensitive to 2 particular types of bacteria that have been isolated in demodex mites. This study further establishes that a reaction to the bacteria correlates to ocular …

3. Light Masque: a LED array from the future

April 27th, 2010, by David Pascoe

The Daily Mail has a recent article looking at a futuristic LED array that wraps around your whole face. Along with a brief review of the device, the author finds it hard to wrap their mind around the claimed …

4. NHS should stop funding Homeopathy: MPs

April 26th, 2010, by David Pascoe

A recent submission to the House of Commons Science and Technology Committee has said that using public money on the highly-diluted remedies of homeopathy could not be justified. The cross-party group said there was no evidence beyond a placebo effect, when a patient gets better because of …

5. NRS Announces 2010 Research Grants

April 23rd, 2010, by David Pascoe

The National Rosacea Society has announced a new round of grant funding. Three new studies have been given a grant as well as continuing the ongoing research of 3 studies. Research Grants Awarded Thursday, April 22, 2010 The National Rosacea Society (NRS) has awarded funding to three new studies and continues to fund three …

6. RRDi journal Issue 1 Review: an unfortunate mix

April 21st, 2010, by David Pascoe

The RRDi recently published the first issue of their journal. Rosacea News was given a pre-print version to review. Volume 1, Number 1 is 88 pages and is available for around $15. I was quietly hopeful that a publication `produced by volunteers and written by dermatologists, physicians, researchers and patients’ could be something worthwhile and progressive for the field of rosacea. Sadly my …

7. Accutane Dose 22mg a day compares well to low doses of Doxycycline

April 20th, 2010, by David Pascoe

A paper that Rosacea News previewed in November last year: Accutane dose of 22mg a day works best: EADV has now been published in the JDDG: Journal of German Society of Dermatology. As we learned from the …

8. Every cloud has a silver lining

April 18th, 2010, by E.L. Hodge

European rosaceans unable to fly right now might temper their frustration with the thought that the subtle atmospheric changes caused by the eruption of Eyjafjallajökull might just be helping their symptoms. The volcanic stuff being spewed into the air is rich in sulphurous materials. Sulphur, of course, is a well established rosacea topical. Now, you may be sure that this is no desperate effort …

9. Cure Your Rosacea: ebook review

April 16th, 2010, by David Pascoe

I was sent a copy of the ebook that is for sale at www.cureyourrosacea.com to review. Here are my thoughts on what the author says took 10 years to discover and write. I wasn’t that thrilled to see the web site that sells this ebook sporting a blue+yellow sunflower theme. The sunflower theme has branded rosacea-support.org for several years now and I …

10. Signum Biosciences developing SIG990 for Rosacea

April 15th, 2010, by David Pascoe

A company called Signum Biosciences is developing a new product to target rosacea. Based on a technology that they call G-protein Modulators, GPMs are said to “restore signalling imbalances in the cell”. A first generation product called Arazine is soon to become available and a second generation of products are to target rosacea, psoriasis and eczema.

According to Signum Bioscience’s Development Pipeline, SIG990 is in …

11. Placebo Treatments work even if you know they’re fake

April 14th, 2010, by David Pascoe

An interesting piece in the Australian media recently looking at whether treating patients knowingly with placebo treatments might actually offer some benefits. I have always been fascinated with the whole placebo effect. How exactly can our belief …

12. Inkjet that Sprays on Skin Cells for Burn Victims

April 12th, 2010, by David Pascoe

A press release via Reuters details a new and exciting alternative to skin grafts for burn victims. The method includes some stem cells which allows hair follicles and sebaceous glands to develop in the new layers of skin.

This development offers another possible avenue for rosacea treatments similar …

13. Face Transplant Recipient gets donor’s Rosacea

April 10th, 2010, by E.L. Hodge

As we all well know there are lots of things worse than rosacea. And, it turns out that one of the things worse than rosacea is having half a face. You see, James Maki who last year received a partial face transplant reports that, in spite of now being permanently red faced on account of the donor being a rosacean, he is very pleased …

14. Oracea and Metrogel FREE for low income no insurance

April 9th, 2010, by David Pascoe

Being prescription items, Oracea and Metrogel 1% are too expensive for many rosacea sufferers, even those with basic medical insurance.

Thanks to a tip from chenoarae; Oracea and Metrogel 1% are both available for free for residents of the US who don’t have insurance of any sort and are on a low income.

Some pharmaceutical companies offer a Patient Assistance Program (PAP) where they provide their …

15. Rosaliac UV Fortifying Anti-Redness Moisturizer with SPF 15

April 8th, 2010, by David Pascoe

La Roche-Posay are not particularly well known in the rosacea world but they do sponsor the National Rosacea Society and have a range …

16. Treating Dry Eye with Intense Pulsed Light

April 7th, 2010, by David Pascoe

KGMH Denver Channel 7 has a piece today, Drop-Free Dry Eye Treatment, highlighting the use of IPL for treating suffers of chronic Dry Eye.

17. Behind the statistics are Real People

April 2nd, 2010, by E.L. Hodge

A.D. 63.  Rome.  Public speaking is central to political and cultural life: an ordeal for most people; a nightmare for Roman rosaceans. The philosopher, Seneca, offers consolation to Lucilius, who is likely afflicted with ruddiness, flushing and blushing. ‘Certain people have ordinary blood,’ he says, ‘ and others just have an animated, lively sort of blood that comes to the face quickly.’